Publications by authors named "Mark Espeland"

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Intensive Lifestyle Intervention, Cardiac Biomarkers, and Cardiovascular Outcomes in Diabetes: Look AHEAD Cardiac Biomarker Ancillary Study.
Kershaw V Patel, Zainali Chunawala, Subodh Verma, Matthew W Segar, Katelyn R Garcia, Chiadi E Ndumele, Thomas J Wang, James L Januzzi, Antoni Bayes-Genis, Javed Butler

J Am Coll Cardiol· February 2025

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Associations of modifiable lifestyle and clinical factors with cognitive function in adults with type 2 diabetes.
Anahita Golchin, Karen C Johnson, Denise K Houston, Jose A Luchsinger, Kristen M Beavers, Mark A Espeland

J Diabetes Complications· January 2026

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Epigenetic clocks and longitudinal plasma biomarkers of Alzheimer's disease.
Bowei Zhang, Linda K McEvoy, Steve Nguyen, Mark A Espeland, Stephen R Rapp

Alzheimers Dement· December 2025

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Association of body composition trajectories with changes in cognitive performance in the Look AHEAD study.
Morgana Mongraw-Chaffin, Joni K Evans, Heather M Shappell, Mark A Espeland, Kathleen M Hayden

Obesity (Silver Spring)· November 2025

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Nutrition Effects on Brain Outcomes and Recovery in Stroke after Hospitalization (NOURISH): Randomized controlled trial protocol and rationale.
Laurel Cherian, Puja Agarwal, Klodian Dhana, Vincent Carey, Mark A Espeland

Contemp Clin Trials· November 2025

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The association between social engagement and cognition in older adults: examining sex and ethnoracial group as moderators.
Jasmine S Dixon, Rebecca E Amariglio, Marjorie Howard, Kira Cella, Sarah Tomaszewski Farias, Mark A Espeland

J Gerontol B Psychol Sci Soc Sci· November 2025

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Late-life Disability following the Action for Health in Diabetes (Look AHEAD) Trial.
Charles T Semelka, Rebecca H Neiberg, HarLeigh D Haynie, Stephen B Kritchevsky, Peter J Huckfeldt, Mark A Espeland

J Gerontol A Biol Sci Med Sci· November 2025

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Cardiac Biomarkers, Intensive Lifestyle Intervention, and Heart Failure Subtypes in Diabetes: Look AHEAD Cardiac Biomarker Ancillary Study.
Zainali Chunawala, Kershaw V Patel, Katelyn R Garcia, Matthew W Segar, Subodh Verma, Mark Espeland

JACC Heart Fail· November 2025

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Sex specific associations of sex hormones with brain volumes and cerebral blood flow: A cross sectional observational study within the look AHEAD type 2 diabetes cohort.
Dhananjay Vaidya, Yvette Yeboah-Kordieh, Marjorie Howard, Christina E Hugenschmidt, Paul A Nyquist, Mark A Espeland

J Diabetes Complications· October 2025

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Sex differences in NT-proBNP associations with risk of heart failure subtypes and response to an intensive lifestyle intervention in type 2 diabetes and overweight or obesity: a post-hoc analysis of the Look AHEAD trial: Sex differences, NT-proBNP, HF subtypes in T2D.
Zainali Chunawala, Kershaw V Patel, Katelyn R Garcia, Neil Keshvani, Mark Espeland

J Card Fail· October 2025

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Multi-site video-based assessment with the NACC UDS-Version 3 battery: Design and participant experience in the V-Cog study.
Bonnie C Sachs, Lauren A Latham, Scott Isom, Lindsay R Clark, Suzanne Craft, Mark A Espeland

Alzheimers Dement· October 2025

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Epigenetic clocks of biological aging and risk of incident mild cognitive impairment and dementia: the Women's Health Initiative Memory Study.
Steve Nguyen, Ake Lu, Steve Horvath, Mark A Espeland, Stephen R Rapp

medRxiv· October 2025

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MicroRNA cargo in neuron-derived vesicles as peripheral biomarkers of brain insulin dysregulation.
Jacob Alexander Cleary, Ashish Kumar, Yixin Su, Sangeeta Singh, Fang-Chi Hsu, Mark A Espeland

Alzheimers Dement· September 2025

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Correlating Magnetoencephalography, Diffusion Kurtosis Imaging, Biomechanics, and Neuropsychology in American Youth Football.
Natalie M Bell, Fang F Yu, Yin Xi, Amy L Proskovec, James M Holcomb, Mark A Espeland

J Neurotrauma· August 2025

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Structured vs Self-Guided Multidomain Lifestyle Interventions for Global Cognitive Function: The US POINTER Randomized Clinical Trial.
Laura D Baker, Mark A Espeland, Rachel A Whitmer, Heather M Snyder, Xiaoyan Leng

JAMA· August 2025

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Epigenetic clocks and longitudinal plasma biomarkers of Alzheimer's disease.
Bowei Zhang, Linda K McEvoy, Steve Nguyen, Mark A Espeland, Stephen R Rapp

medRxiv· August 2025

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Baseline cognition and demographic, lifestyle, and cardiovascular risk factors in US POINTER.
Kathryn V Papp, Sarah Tomaszewski Farias, Marjorie Howard, Amber Thro, Tiia Ngandu, Mark A Espeland

Alzheimers Dement· July 2025

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Comparative Effectiveness of Metformin Versus Sulfonylureas on Exceptional Longevity in Women With Type 2 Diabetes: Target Trial Emulation.
Aladdin H Shadyab, Mark A Espeland, Andrew O Odegaard, JoAnn E Manson, Bernhard Haring

J Gerontol A Biol Sci Med Sci· June 2025

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Baseline characteristics of the U.S. Study to Protect Brain Health Through Lifestyle Intervention to Reduce Risk (U.S. POINTER): Successful enrollment of a diverse clinical trial cohort at risk for cognitive decline.
Rachel A Whitmer, Laura D Baker, Maria C Carrillo, Heather M Snyder, MaryJo L Cleveland, Mark Andrew Espeland

Alzheimers Dement· June 2025

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Development of a multimorbidity health conditions outcome index for caloric restriction interventional studies in older adults: a preliminary investigation in an observational cohort study.
Michael E Miller, Haiying Chen, Mark A Espeland, Fang-Chi Hsu, Denise K Houston

Geroscience· May 2025

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An Expert Consensus Statement on Biomarkers of Aging for Use in Intervention Studies.
Giorgia Perri, Chloe French, César Agostinis-Sobrinho, Atul Anand, Radiana Dhewayani Antarianto, Mark A Espeland

J Gerontol A Biol Sci Med Sci· April 2025

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Associations between decreases in adiposity and reductions in HbA1c and insulin use in the Look AHEAD cohort.
Rebecca Palmer, Rebecca H Neiberg, Kristen M Beavers, Steven E Kahn, Denise K Houston, Mark A Espeland

Obesity (Silver Spring)· March 2025

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Machine learning reveals distinct neuroanatomical signatures of cardiovascular and metabolic diseases in cognitively unimpaired individuals.
Sindhuja Tirumalai Govindarajan, Elizabeth Mamourian, Guray Erus, Ahmed Abdulkadir, Randa Melhem, Mark A Espeland

Nat Commun· March 2025

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Alzheimer Disease Blood Biomarkers and Cognition Among Individuals With Diabetes and Overweight or Obesity.
Michelle M Mielke, Joni K Evans, Rebecca H Neiberg, Doris P Molina-Henry, Santica M Marcovina, Mark A Espeland

JAMA Netw Open· February 2025

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Selecting Appropriate Clinical Trial Endpoints for Geroscience Trials: A Path Towards Consensus.
Stephen Kritchevsky, Ezequiel Zamora, Shalender Bhasin, Alan Cohen, Allison Chandler, Mark Espeland

Res Sq· February 2025

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The U.S. POINTER neurovascular ancillary study: Study design and methods.
Tina E Brinkley, Katelyn R Garcia, Gary F Mitchell, Charles H Tegeler, Aarti Sarwal, Mark A Espeland

Alzheimers Dement· February 2025

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