J Am Coll Cardiol February 2025 PMID 39551169

Intensive Lifestyle Intervention, Cardiac Biomarkers, and Cardiovascular Outcomes in Diabetes: Look AHEAD Cardiac Biomarker Ancillary Study.

Kershaw V Patel, Zainali Chunawala, Subodh Verma, Matthew W Segar, Katelyn R Garcia, Chiadi E Ndumele, Thomas J Wang, James L Januzzi, Antoni Bayes-Genis, Javed Butler, Carolyn S P Lam, Christie M Ballantyne, James A de Lemos, Alain G Bertoni, Mark Espeland

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Mentions

Peak: 9 in Nov 2024

across 4 sources since Nov 2024

Extended reach

283,037

potential audience

Total likes

Video views

636

Mentions per month

Nov 2024 – Aug 2025

Where it's discussed

X / Twitter10 posts
News5 articles
YouTube2 videos
Blogs2 articles

AI synopsis

What people are saying

The discussions include mentions of lifestyle changes improving heart health markers, with posts like 'Lifestyle changes can improve heart health in diabetes' and references to expert analyses of the results. The tone shows an appreciation for the study's relevance, although some posts primarily share summaries or links, reflecting a moderate level of involvement and recognition of this research's significance.

AgreementModerate agreement

Most discussions highlight the positive effects of lifestyle interventions on cardiac biomarkers and overall health in diabetes, showing general consensus.

InterestModerate interest

Posts reveal moderate interest, with some sharing links and summaries of the study's findings, but lacking deep personal insights.

EngagementModerate engagement

Discussions include references to study results, expert opinions, and calls to follow ongoing research, indicating a fair level of engagement.

ImpactModerate impact

Many posts emphasize the potential implications for diabetes management and cardiovascular risk reduction, suggesting a moderate perceived impact.

Abstract in brief

This study examined how an intensive lifestyle intervention (ILI) targeting weight loss impacts cardiac biomarkers (NTproBNP and high-sensitivity cardiac troponin T) in people with type 2 diabetes, and how changes in these biomarkers relate to cardiovascular outcomes.
Results showed that ILI caused a temporary increase in NTproBNP at 1 year, which lessened by 4 years, while it also led to a decrease in hscTnT at both 1 and 4 years. Participants who experienced significant weight loss (over 5%) at 1 year had boosted NTproBNP initially but improved long-term levels of hscTnT, suggesting a potential link between weight loss, biomarker changes, and cardiovascular risk reduction.
The study highlights that changes in these cardiac biomarkers, particularly increases in NTproBNP and decreases in hscTnT associated with weight loss, are related to the risk of cardiovascular events in people with type 2 diabetes, emphasizing the importance of lifestyle interventions in managing cardiovascular health.]

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All mentions

Impact of Lifestyle Intervention on Cardiac Biomarkers in Diabetes Management

This study examines how an intensive lifestyle intervention targeting weight loss influences cardiac biomarkers, NTproBNP and hscTnT, and their relation to cardiovascular risks in type 2 diabetes patients over four…

American College of Cardiology · Nov 16, 2024 543 views

Innovative Approaches in Women's Health and Heart Management

Halle Tecco discusses her work connecting technology and healthcare, including a venture that allows women to freeze their eggs for free by donating. The video also addresses how obesity increases heart failure risk…

Yale Insights · Nov 21, 2024 93 views

Subodh Verma

@SubodhVermaMD · X

Intensive Lifestyle Intervention, Cardiac Biomarkers, and Cardiovascular Outcomes in Diabetes: Look AHEAD Cardiac Biomarker Ancillary Study | JACC https://t.co/jkjGGB6Xfb

Aug 5, 2025 · 3 likes · 1,213 followers View post →

Heart News

@HearttNews · X

Intensive lifestyle changes can improve heart health markers and outcomes in diabetes patients, says Look AHEAD study. #Diabetes #HeartHealth #LifestyleChanges https://t.co/Rz3U5q55BY https://t.co/v3exwDhq2G

Apr 2, 2025 · 9 followers View post →

أخبار القلب

@A5barEl2alb · X

التغييرات الشديدة في النمط الحياتي يمكن أن تحسن مؤشرات صحة القلب والنتائج في مرضى السكري، وفقا لدراسة Look AHEAD. #السكري #صحة_القلب #تغييرات_نمط_الحياة https://t.co/PiidDPVjnR https://t.co/l1RSuVQaIB

Apr 2, 2025 · 1 followers View post →

David McNamara

@davidmcnam · X

RT @JACCJournals: #AHA24 ICYMI: #JACC AE Dr. @mvaduganathan & Dr. Ambarish Pandey, @UTSWMedCenter discuss results from the #LookAHEAD trial…

Nov 17, 2024 · 2 shares · 344 followers View post →

Henry Han

@HanCardiomd · X

RT @JACCJournals: #AHA24 ICYMI: #JACC AE Dr. @mvaduganathan & Dr. Ambarish Pandey, @UTSWMedCenter discuss results from the #LookAHEAD trial…

Nov 17, 2024 · 2 shares · 16,144 followers View post →

JACC Journals

@JACCJournals · X

#AHA24 ICYMI: #JACC AE Dr. @mvaduganathan & Dr. Ambarish Pandey, @UTSWMedCenter discuss results from the #LookAHEAD trial examining cardiac biomarker change after lifestyle intervention

Nov 17, 2024 · 16 likes · 2 shares · 114,737 followers View post →

Juan Carlos Obaya

@jcobaya69 · X

RT @hmkyale: @NEJM Here is the link @JACCJournals: https://t.co/vLJxhasELH

Nov 16, 2024 · 1 share · 858 followers View post →

Harlan Krumholz

@hmkyale · X

@NEJM Here is the link @JACCJournals: https://t.co/vLJxhasELH

Nov 16, 2024 · 1 like · 1 share · 26,543 followers View post →

Sherry-Ann Brown, MD, PhD, FACC, FAHA

@drbrowncares · X

RT @JACCJournals: #AHA24: How do cardiac biomarkers change after lifestyle intervention? In #JACC, Dr. @kershawpatel, et al present results…

Nov 15, 2024 · 5 shares · 7,779 followers View post →