Publications by authors named "Mark Iles"

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Mapping chromatin interactions at melanoma susceptibility loci uncovers distant cis-regulatory gene targets.
Rohit Thakur, Mai Xu, Hayley Sowards, Joshuah Yon, Lea Jessop, Mark M Iles

Am J Hum Genet· July 2025

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Integrating 12 Spatial and Single Cell Technologies to Characterise Tumour Neighbourhoods and Cellular Interactions in three Skin Cancer Types.
P Prakrithi, Laura F Grice, Feng Zhang, Levi Hockey, Samuel X Tan, Mark M Iles

bioRxiv· July 2025

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Correction to: Genetic risk factors for periodontitis: a genome-wide association study using UK Biobank data.
Chenyi Gao, Mark M Iles, David Timothy Bishop, Harriet Larvin, David Bunce

Clin Oral Investig· March 2025

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Age, anticoagulants, hypertension and cardiovascular genetic traits predict cranial ischaemic complications in patients with giant cell arteritis.
Natalie J M Chaddock, Charlotte J Harden, Louise Sorensen, Hannah R Mathieson, Michal Zulcinski, Mark M Iles

Ann Rheum Dis· February 2025

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Genetic risk factors for periodontitis: a genome-wide association study using UK Biobank data.
Chenyi Gao, Mark M Iles, David Timothy Bishop, Harriet Larvin, David Bunce

Clin Oral Investig· February 2025

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A large-scale genome-wide association meta-analysis for nevus count provides direct insights into the genetics of melanoma.
G J M S R Jayasinghe, Gu Zhu, Nirmala Pandeya, Catherine M Olsen, Nicholas G Martin, Mark M Iles

medRxiv· February 2025

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Minimally Invasive Surgery for Colorectal Cancer: Benchmarking Uptake for a Regional Improvement Programme.
John C Taylor, Dermot Burke, Lene H Iversen, Rebecca J Birch, Paul J Finan, Mark M Iles

Clin Colorectal Cancer· December 2024

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Plasma MERTK is causally associated with infection mortality.
Michael Drozd, Fergus Hamilton, Chew W Cheng, Patrick J Lillie, Oliver I Brown, Mark M Iles

J Infect· November 2024

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Polygenic Risk Score Improves Melanoma Risk Assessment in a Patient Cohort from the Veneto Region of Italy.
Stefania Pellegrini, Thomas P Potjer, Paola Del Bianco, Antonella Vecchiato, Alessio Fabozzi, Mark M Iles

Biology (Basel)· November 2024

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Mapping chromatin interactions at melanoma susceptibility loci and cell-type specific dataset integration uncovers distant gene targets of -regulation.
Rohit Thakur, Mai Xu, Hayley Sowards, Joshuah Yon, Lea Jessop, Mark M Iles

medRxiv· November 2024

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Genome-wide association studies on periodontitis: A systematic review.
Chenyi Gao, Mark Iles, Harriet Larvin, David Timothy Bishop, David Bunce

PLoS One· September 2024

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Risk loci involved in giant cell arteritis susceptibility: a genome-wide association study.
Gonzalo Borrego-Yaniz, Lourdes Ortiz-Fernández, Adela Madrid-Paredes, Martin Kerick, José Hernández-Rodríguez, Mark Iles

Lancet Rheumatol· June 2024

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Uncovering the complex relationship between balding, testosterone and skin cancers in men.
Jue-Sheng Ong, Mathias Seviiri, Jean Claude Dusingize, Yeda Wu, Xikun Han, Mark M Iles

Nat Commun· October 2023

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Genetic variants for smoking behaviour and risk of skin cancer.
Jean Claude Dusingize, Matthew H Law, Mathias Seviiri, Catherine M Olsen, Nirmala Pandeya, Mark M Iles

Sci Rep· October 2023

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Population-based analysis of variants in a cutaneous melanoma case-control cohort.
Irving Simonin-Wilmer, Raul Ossio, Emmett M Leddin, Mark Harland, Karen A Pooley, Mark M Iles

J Med Genet· July 2023

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Genome-wide analyses characterize shared heritability among cancers and identify novel cancer susceptibility regions.
Sara Lindström, Lu Wang, Helian Feng, Arunabha Majumdar, Sijia Huo, Mark M Iles

J Natl Cancer Inst· June 2023

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Metabolic drivers of dysglycemia in pregnancy: ethnic-specific GWAS of 146 metabolites and 1-sample Mendelian randomization analyses in a UK multi-ethnic birth cohort.
Harriett Fuller, Mark M Iles, J Bernadette Moore, Michael A Zulyniak

Front Endocrinol (Lausanne)· June 2023

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The association between genetically elevated polyunsaturated fatty acids and risk of cancer.
Philip C Haycock, Maria Carolina Borges, Kimberley Burrows, Rozenn N Lemaitre, Stephen Burgess, Mark M Iles

EBioMedicine· May 2023

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Investigation of Shared Genetic Risk Factors Between Parkinson's Disease and Cancers.
Pierre-Emmanuel Sugier, Elise A Lucotte, Cloé Domenighetti, Matthew H Law, Mark M Iles

Mov Disord· April 2023

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Somatostatin Receptor PET/MR Imaging of Inflammation in Patients With Large Vessel Vasculitis and Atherosclerosis.
Andrej Ćorović, Christopher Wall, Meritxell Nus, Deepa Gopalan, Yuan Huang, Mark Iles

J Am Coll Cardiol· January 2023

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Massively parallel reporter assays and variant scoring identified functional variants and target genes for melanoma loci and highlighted cell-type specificity.
Erping Long, Jinhu Yin, Karen M Funderburk, Mai Xu, James Feng, Mark M Iles

Am J Hum Genet· December 2022

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Unique Metabolic Profiles Associate with Gestational Diabetes and Ethnicity in Low- and High-Risk Women Living in the UK.
Harriett Fuller, Mark Iles, J Bernadette Moore, Michael A Zulyniak

J Nutr· October 2022

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Higher polygenic risk for melanoma is associated with improved survival in a high ultraviolet radiation setting.
Mathias Seviiri, Richard A Scolyer, D Timothy Bishop, Julia A Newton-Bishop, Mark M Iles

J Transl Med· September 2022

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Differences in the management of patients requiring an emergency resection for colonic cancer in two European populations.
John C Taylor, Lene H Iversen, Dermot Burke, Paul J Finan, Mark M Iles

BJS Open· September 2022

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Ethnic-specific associations between dietary consumption and gestational diabetes mellitus incidence: A meta-analysis.
Harriett Fuller, J Bernadette Moore, Mark M Iles, Michael A Zulyniak

PLOS Glob Public Health· May 2022

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