Publications by authors named "Mark L Lewis"

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Discovery and Optimization of Selective Nav1.8 Modulator Series That Demonstrate Efficacy in Preclinical Models of Pain.
Sharan K Bagal, Peter J Bungay, Stephen M Denton, Karl R Gibson, Melanie S Glossop, Mark L Lewis

ACS Med Chem Lett· June 2015

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Optimisation of a novel series of selective CNS penetrant CB(2) agonists.
Christine Watson, Dafydd R Owen, Denise Harding, Kana Kon-I, Mark L Lewis

Bioorg Med Chem Lett· July 2011

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Structural pairwise comparisons of HLM stability of phenyl derivatives: Introduction of the Pfizer metabolism index (PMI) and metabolism-lipophilicity efficiency (MLE).
Mark L Lewis, Lourdes Cucurull-Sanchez

J Comput Aided Mol Des· February 2009

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A novel series of highly selective inhibitors of MMP-3.
Gavin A Whitlock, Kevin N Dack, Roger P Dickinson, Mark L Lewis

Bioorg Med Chem Lett· December 2007

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Predicting penetration across the blood-brain barrier from simple descriptors and fragmentation schemes.
Yuan H Zhao, Michael H Abraham, Adam Ibrahim, Paul V Fish, Susan Cole, Mark L Lewis

J Chem Inf Model· May 2007

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