Publications by authors named "Mark Lessard"

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An integrated platform for high-throughput nanoscopy.
Andrew E S Barentine, Yu Lin, Edward M Courvan, Phylicia Kidd, Miao Liu, Mark Lessard

Nat Biotechnol· November 2023

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Precision analysis of mutant U2AF1 activity reveals deployment of stress granules in myeloid malignancies.
Giulia Biancon, Poorval Joshi, Joshua T Zimmer, Torben Hunck, Yimeng Gao, Mark D Lessard

Mol Cell· March 2022

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Three-dimensional adaptive optical nanoscopy for thick specimen imaging at sub-50-nm resolution.
Xiang Hao, Edward S Allgeyer, Dong-Ryoung Lee, Jacopo Antonello, Katherine Watters, Mark D Lessard

Nat Methods· June 2021

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Implementation of a 4Pi-SMS super-resolution microscope.
Jingyu Wang, Edward S Allgeyer, George Sirinakis, Yongdeng Zhang, Kevin Hu, Mark D Lessard

Nat Protoc· February 2021

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Nanoscale subcellular architecture revealed by multicolor three-dimensional salvaged fluorescence imaging.
Yongdeng Zhang, Lena K Schroeder, Mark D Lessard, Phylicia Kidd, Jeeyun Chung

Nat Methods· February 2020

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3D mapping of nanoscale crosslink heterogeneities in microgels.
Apostolos A Karanastasis, Yongdeng Zhang, Gopal S Kenath, Mark D Lessard, Joerg Bewersdorf

Mater Horiz· November 2018

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Assessing photodamage in live-cell STED microscopy.
Nicole Kilian, Alexander Goryaynov, Mark D Lessard, Giles Hooker, Derek Toomre

Nat Methods· October 2018

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A novel physiological role for ARF1 in the formation of bidirectional tubules from the Golgi.
Francesca Bottanelli, Nicole Kilian, Andreas M Ernst, Felix Rivera-Molina, Lena K Schroeder, Mark D Lessard

Mol Biol Cell· June 2017

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Ultra-High Resolution 3D Imaging of Whole Cells.
Fang Huang, George Sirinakis, Edward S Allgeyer, Lena K Schroeder, Whitney C Duim, Mark Lessard

Cell· August 2016

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Hypoxic HepG2 cell adaptation decreases ATP synthase dimers and ATP production in inflated cristae by mitofilin down-regulation concomitant to MICOS clustering.
Lydie Plecitá-Hlavatá, Hana Engstová, Lukáš Alán, Tomáš Špaček, Andrea Dlasková, Mark Lessard

FASEB J· May 2016

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Distribution of mitochondrial DNA nucleoids inside the linear tubules vs. bulk parts of mitochondrial network as visualized by 4Pi microscopy.
Andrea Dlasková, Hana Engstová, Lydie Plecitá-Hlavatá, Mark Lessard, Lukáš Alán

J Bioenerg Biomembr· June 2015

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p63(+)Krt5(+) distal airway stem cells are essential for lung regeneration.
Wei Zuo, Ting Zhang, Daniel Zheng'An Wu, Shou Ping Guan, Audrey-Ann Liew, Mark Lessard

Nature· January 2015

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3-Dimensional histological reconstruction and imaging of the murine pancreas.
Steven L Ciciotte, Mark Lessard, Ellen C Akeson, Elizabeth Cameron, Timothy M Stearns

Mamm Genome· October 2014

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A new approach for the study of the chemical composition of bordered pit membranes: 4Pi and confocal laser scanning microscopy.
Daniela Maschek, Barry Goodell, Jody Jellison, Mark Lessard, Holger Militz

Am J Bot· September 2013

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The impact of entropy on the spatial organization of synaptonemal complexes within the cell nucleus.
Miriam Fritsche, Laura G Reinholdt, Mark Lessard, Mary Ann Handel, Jörg Bewersdorf

PLoS One· September 2012

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Activation-induced cytidine deaminase-initiated off-target DNA breaks are detected and resolved during S phase.
Muneer G Hasham, Kathy J Snow, Nina M Donghia, Jane A Branca, Mark D Lessard

J Immunol· September 2012

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4Pi microscopy reveals an impaired three-dimensional mitochondrial network of pancreatic islet beta-cells, an experimental model of type-2 diabetes.
Andrea Dlasková, Tomás Spacek, Jitka Santorová, Lydie Plecitá-Hlavatá, Zuzana Berková, Mark Lessard

Biochim Biophys Acta· January 2011

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Centriolar association of ALMS1 and likely centrosomal functions of the ALMS motif-containing proteins C10orf90 and KIAA1731.
Victoria J Knorz, Cosma Spalluto, Mark Lessard, Tracey L Purvis, Fiona F Adigun

Mol Biol Cell· November 2010

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Bone marrow expressing a diabetes resistance MHC class II allele: diabetes deviation by chronic immune stimulation.
Peter Reifsnyder, William Schott, Darcy Pomerleau, Mark D Lessard, Brian W Soper

Novartis Found Symp· March 2009

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Mitochondrial oxidative phosphorylation and energetic status are reflected by morphology of mitochondrial network in INS-1E and HEP-G2 cells viewed by 4Pi microscopy.
Lydie Plecitá-Hlavatá, Mark Lessard, Jitka Santorová, Joerg Bewersdorf, Petr Jezek

Biochim Biophys Acta· August 2008

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Three-dimensional sub-100 nm resolution fluorescence microscopy of thick samples.
Manuel F Juette, Travis J Gould, Mark D Lessard, Michael J Mlodzianoski, Bhupendra S Nagpure

Nat Methods· June 2008

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Tissue refractometry using Hilbert phase microscopy.
Niyom Lue, Joerg Bewersdorf, Mark D Lessard, Kamran Badizadegan, Ramachandra R Dasari

Opt Lett· December 2007

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Attenuation of murine lysosomal storage disease by allogeneic neonatal bone marrow transplantation using costimulatory blockade and donor lymphocyte infusion without myeloablation.
Mark D Lessard, Travis L Alley, Jennifer L Proctor, Beth Levy, Nancy Galvin

Clin Immunol· May 2006

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Early onset of lysosomal storage disease in a murine model of mucopolysaccharidosis type VII: undegraded substrate accumulates in many tissues in the fetus and very young MPS VII mouse.
Carole Vogler, Beth Levy, Nancy Galvin, Mark Lessard, Brian Soper

Pediatr Dev Pathol· December 2005

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Transplanted ER-MP12hi20-58med/hi myeloid progenitors produce resident macrophages from marrow that are therapeutic for lysosomal storage disease.
Brian W Soper, Ted M Duffy, Mark D Lessard, Craig D Jude, Adam J T Schuldt

Blood Cells Mol Dis· September 2004

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