Publications by authors named "Mark McCarthy"

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Can compassionate leadership of senior hospital leaders help retain trainee doctors?
Wen Wang, Jennifer Creese, Maria Karanika-Murray, Kevin Harris, Mark McCarthy

BMJ Lead· September 2025

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Polygenic prediction of body mass index and obesity through the life course and across ancestries.
Roelof A J Smit, Kaitlin H Wade, Qin Hui, Joshua D Arias, Xianyong Yin, Mark I McCarthy

Nat Med· September 2025

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Clonal hematopoiesis is associated with reduced response to atezolizumab in non-small cell lung cancer.
Vylyny Chat, Kipper Fletez-Brant, Minu Srivastava, Barzin Nabet, Ira Mellman, Mark I McCarthy

J Immunother Cancer· September 2025

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Accelerating Medicines Partnership in Type 2 Diabetes and Common Metabolic Diseases: Collaborating to Maximize the Value of Genetic and Genomic Data.
Maria C Costanzo, Beena Akolkar, Melina Claussnitzer, Jose C Florez, Anna L Gloyn, Mark I McCarthy

Diabetes· July 2025

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Bayesian network imputation methods applied to multi-omics data identify putative causal relationships in a type 2 diabetes dataset containing incomplete data: An IMI DIRECT Study.
Richard Howey, Jonathan Adam, Jerzy Adamski, Natalie N Atabaki, Søren Brunak, Mark I McCarthy

PLoS Genet· July 2025

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The dynamics of the gut microbiota in prediabetes during a four-year follow-up among European patients-an IMI-DIRECT prospective study.
Liwei Lyu, Yong Fan, Josef Korbinian Vogt, Marc Clos-Garcia, Amelie Bonnefond, Mark I McCarthy

Genome Med· July 2025

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Multi-ancestry polygenic risk scores for the prediction of type 2 diabetes and complications in diverse ancestries.
Alicia Huerta-Chagoya, Joohyun Kim, Ravi Mandla, Yingchang Lu, Ken Suzuki, Mark I McCarthy

medRxiv· July 2025

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Genetic associations of neuropathic pain and sensory profile in a deeply phenotyped neuropathy cohort.
Mikael Åkerlund, Georgios Baskozos, Wenqianglong Li, Andreas C Themistocleous, Mathilde M V Pascal, Mark I McCarthy

Pain· June 2025

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A Biological-Systems-Based Analyses Using Proteomic and Metabolic Network Inference Reveals Mechanistic Insights into Hepatic Lipid Accumulation: An IMI-DIRECT Study.
Natalie N Atabaki, Daniel E Coral, Hugo Pomares-Millan, Kieran Smith, Harry H Behjat, Mark I McCarthy

medRxiv· June 2025

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Integration of biobank-scale genetics and plasma proteomics reveals evidence for causal processes in asthma risk and heterogeneity.
Lauren J Donoghue, Christian Benner, Diana Chang, Flaviyan Jerome Irudayanathan, Rion K Pendergrass, Mark I McCarthy

Cell Genom· May 2025

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Large-scale multi-omics analyses in Hispanic/Latino populations identify genes for cardiometabolic traits.
Lauren E Petty, Hung-Hsin Chen, Elizabeth G Frankel, Wanying Zhu, Carolina G Downie, Mark I McCarthy

Nat Commun· April 2025

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Experimental evidence of the role of nitrogen for eutrophication in shallow lakes: A long-term climate effect mesocosm study.
Erik Jeppesen, Hu He, Martin Søndergaard, Torben L Lauridsen, Thomas A Davidson, Mark J McCarthy

Innovation (Camb)· April 2025

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Genome-wide association study of Idiopathic Pulmonary Fibrosis susceptibility using clinically-curated European-ancestry datasets.
Daniel Chin, Tamara Hernandez-Beeftink, Lauren Donoghue, Beatriz Guillen-Uio, Olivia C Leavy, Mark McCarthy

medRxiv· February 2025

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Optimizing approaches for targeted integration of transgenic cassettes by integrase-mediated cassette exchange in mouse and human stem cells.
Phalguni Rath, Philipp Kramer, Daniel Biggs, Chris Preece, Nicole Hortin, Mark McCarthy

Stem Cells· January 2025

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Role of human plasma metabolites in prediabetes and type 2 diabetes from the IMI-DIRECT study.
Sapna Sharma, Qiuling Dong, Mark Haid, Jonathan Adam, Roberto Bizzotto, Mark I McCarthy

Diabetologia· December 2024

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SLC16A8 is a causal contributor to age-related macular degeneration risk.
Navid Nouri, Bailey Hannon Gussler, Amy Stockwell, Tom Truong, Gyeong Jin Kang, Mark I McCarthy

NPJ Genom Med· October 2024

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Integrated clinical risk prediction of type 2 diabetes with a multifactorial polygenic risk score.
Scott C Ritchie, Henry J Taylor, Yujian Liang, Hasanga D Manikpurage, Lisa Pennells, Mark I McCarthy

medRxiv· September 2024

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Drivers and mechanisms of harmful algal blooms across hydrologic extremes in hypereutrophic grand lake st marys (Ohio).
Silvia E Newell, Jason C Doll, Morgan C Jutte, Joseph L Davidson, Mark J McCarthy

Harmful Algae· September 2024

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Publisher Correction: Understanding the genetic complexity of puberty timing across the allele frequency spectrum.
Katherine A Kentistou, Lena R Kaisinger, Stasa Stankovic, Marc Vaudel, Edson Mendes de Oliveira, Mark I McCarthy

Nat Genet· August 2024

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Single cell multiome profiling of pancreatic islets reveals physiological changes in cell type-specific regulation associated with diabetes risk.
Hannah M Mummey, Weston Elison, Katha Korgaonkar, Ruth M Elgamal, Parul Kudtarkar, Mark I McCarthy

bioRxiv· August 2024

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Understanding the genetic complexity of puberty timing across the allele frequency spectrum.
Katherine A Kentistou, Lena R Kaisinger, Stasa Stankovic, Marc Vaudel, Edson Mendes de Oliveira, Mark I McCarthy

Nat Genet· July 2024

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Autoimmune hypothyroidism GWAS reveals independent autoimmune and thyroid-specific contributions and an inverse relation with cancer risk.
Mary Reeve, Masahiro Kanai, Daniel Graham, Juha Karjalainen, Shuang Luo, Mark McCarthy

Res Sq· July 2024

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Multi-omics characterization of type 2 diabetes associated genetic variation.
Ravi Mandla, Kim Lorenz, Xianyong Yin, Ozvan Bocher, Alicia Huerta-Chagoya, Mark I McCarthy

medRxiv· July 2024

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Author Correction: Trans-ancestral genome-wide association study of longitudinal pubertal height growth and shared heritability with adult health outcomes.
Jonathan P Bradfeld, Rachel L Kember, Anna Ulrich, Zhanna Balkhiyarova, Akram Alyass, Mark I McCarthy

Genome Biol· May 2024

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Large-scale exome array summary statistics resources for glycemic traits to aid effector gene prioritization.
Sara M Willems, Natasha H J Ng, Juan Fernandez, Rebecca S Fine, Eleanor Wheeler, Mark I McCarthy

Wellcome Open Res· October 2023

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