Publications by authors named "Mark Okon"

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Sortase-mediated segmental labeling: A method for segmental assignment of intrinsically disordered regions in proteins.
Kristina V Boyko, Erin A Rosenkranz, Derrick M Smith, Heather L Miears, Melissa Oueld Es Cheikh, Mark Okon

PLoS One· July 2024

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Biophysical characterization of the ETV6 PNT domain polymerization interfaces.
Chloe A N Gerak, Sophia Y Cho, Maxim Kolesnikov, Mark Okon, Michael E P Murphy

J Biol Chem· August 2021

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Discovery of a Highly Conserved Peptide in the Iron Transporter Melanotransferrin that Traverses an Intact Blood Brain Barrier and Localizes in Neural Cells.
Chaahat S B Singh, Brett A Eyford, Thomas Abraham, Lonna Munro, Kyung Bok Choi, Mark Okon

Front Neurosci· June 2021

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Characterization of the Pilotin-Secretin Complex from the Salmonella enterica Type III Secretion System Using Hybrid Structural Methods.
Dorothy D Majewski, Mark Okon, Florian Heinkel, Craig S Robb, Marija Vuckovic

Structure· February 2021

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Ligand- and pH-Induced Structural Transition of Gypsy Moth Pheromone-Binding Protein 1 (LdisPBP1).
Mailyn Terrado, Mark Okon, Lawrence P McIntosh, Erika Plettner

Biochemistry· September 2020

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The pK values of the catalytic residues in the retaining glycoside hydrolase T26H mutant of T4 lysozyme.
Jacob A Brockerman, Mark Okon, Stephen G Withers, Lawrence P McIntosh

Protein Sci· March 2019

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The Biophysical Basis for Phosphorylation-Enhanced DNA-Binding Autoinhibition of the ETS1 Transcription Factor.
Cecilia Perez-Borrajero, Chang Sheng-Huei Lin, Mark Okon, Karlton Scheu, Barbara J Graves

J Mol Biol· February 2019

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Oxidative damage to epigenetically methylated sites affects DNA stability, dynamics and enzymatic demethylation.
David R Gruber, Joanna J Toner, Heather L Miears, Andrey V Shernyukov, Alexey S Kiryutin, Mark Okon

Nucleic Acids Res· November 2018

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Characterization of the two conformations adopted by the T3SS inner-membrane protein PrgK.
Julien R C Bergeron, Jacob A Brockerman, Marija Vuckovic, Wanyin Deng, Mark Okon

Protein Sci· September 2018

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Biophysical Characterization of the Tandem FHA Domain Regulatory Module from the Mycobacterium tuberculosis ABC Transporter Rv1747.
Florian Heinkel, Leo Shen, Melissa Richard-Greenblatt, Mark Okon, Jennifer M Bui

Structure· July 2018

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Modulating the Nucleophile of a Glycoside Hydrolase through Site-Specific Incorporation of Fluoroglutamic Acids.
Miriam P Kötzler, Kyle Robinson, Hong-Ming Chen, Mark Okon, Lawrence P McIntosh

J Am Chem Soc· July 2018

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Plant Villin Headpiece Domain Demonstrates a Novel Surface Charge Pattern and High Affinity for F-Actin.
Heather L Miears, David R Gruber, Nicholas M Horvath, John M Antos, Jeff Young, Mark Okon

Biochemistry· March 2018

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The voltage-gated sodium channel EF-hands form an interaction with the III-IV linker that is disturbed by disease-causing mutations.
Bernd R Gardill, Ricardo E Rivera-Acevedo, Ching-Chieh Tung, Mark Okon, Lawrence P McIntosh

Sci Rep· March 2018

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Structured and disordered regions cooperatively mediate DNA-binding autoinhibition of ETS factors ETV1, ETV4 and ETV5.
Simon L Currie, Desmond K W Lau, Jedediah J Doane, Frank G Whitby, Mark Okon

Nucleic Acids Res· March 2017

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Conformational Dynamics and the Binding of Specific and Nonspecific DNA by the Autoinhibited Transcription Factor Ets-1.
Geneviève Desjardins, Mark Okon, Barbara J Graves, Lawrence P McIntosh

Biochemistry· July 2016

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Structural and Dynamics Studies of Pax5 Reveal Asymmetry in Stability and DNA Binding by the Paired Domain.
Cecilia Perez-Borrajero, Mark Okon, Lawrence P McIntosh

J Mol Biol· June 2016

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Autoinhibition of ETV6 DNA Binding Is Established by the Stability of Its Inhibitory Helix.
Soumya De, Mark Okon, Barbara J Graves, Lawrence P McIntosh

J Mol Biol· April 2016

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Arginine: Its pKa value revisited.
Carolyn A Fitch, Gerald Platzer, Mark Okon, Bertrand E Garcia-Moreno, Lawrence P McIntosh

Protein Sci· May 2015

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The modular structure of the inner-membrane ring component PrgK facilitates assembly of the type III secretion system basal body.
Julien R C Bergeron, Liam J Worrall, Soumya De, Nikolaos G Sgourakis, Adrienne H Cheung, Mark Okon

Structure· January 2015

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pH-dependent random coil (1)H, (13)C, and (15)N chemical shifts of the ionizable amino acids: a guide for protein pK a measurements.
Gerald Platzer, Mark Okon, Lawrence P McIntosh

J Biomol NMR· November 2014

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Synergy of aromatic residues and phosphoserines within the intrinsically disordered DNA-binding inhibitory elements of the Ets-1 transcription factor.
Geneviève Desjardins, Charles A Meeker, Niraja Bhachech, Simon L Currie, Mark Okon

Proc Natl Acad Sci U S A· July 2014

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Steric mechanism of auto-inhibitory regulation of specific and non-specific DNA binding by the ETS transcriptional repressor ETV6.
Soumya De, Anson C K Chan, H Jerome Coyne, Niraja Bhachech, Ulrike Hermsdorf, Mark Okon

J Mol Biol· April 2014

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O-GlcNAc modification of tau directly inhibits its aggregation without perturbing the conformational properties of tau monomers.
Scott A Yuzwa, Adrienne H Cheung, Mark Okon, Lawrence P McIntosh, David J Vocadlo

J Mol Biol· April 2014

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Detection and characterization of serine and threonine hydroxyl protons in Bacillus circulans xylanase by NMR spectroscopy.
Jacob A Brockerman, Mark Okon, Lawrence P McIntosh

J Biomol NMR· January 2014

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Strategies for modulating the pH-dependent activity of a family 11 glycoside hydrolase.
Martin L Ludwiczek, Igor D'Angelo, Gary N Yalloway, Jacob A Brockerman, Mark Okon

Biochemistry· May 2013

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