Publications by authors named "Mark P Labrecque"

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Genetic mechanisms of resistance to targeted KRAS inhibition.
Bianca J Diaz, Max Kops, Sara Bernardo, Henri Schmidt, Elizabeth Grankowsky, Mark P Labrecque

bioRxiv· August 2025

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Targeting the fibroblast growth factor pathway in molecular subtypes of castration-resistant prostate cancer.
Mark P Labrecque, Lisha G Brown, Ilsa M Coleman, Holly M Nguyen, Susan Dalrymple

Prostate· January 2024

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Concurrent Targeting of HDAC and PI3K to Overcome Phenotypic Heterogeneity of Castration-resistant and Neuroendocrine Prostate Cancers.
Ailin Zhang, Nathan A Lau, Alicia Wong, Lisha G Brown, Ilsa M Coleman, Mark P Labrecque

Cancer Res Commun· November 2023

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BET Bromodomain Inhibition Blocks an AR-Repressed, E2F1-Activated Treatment-Emergent Neuroendocrine Prostate Cancer Lineage Plasticity Program.
Dae-Hwan Kim, Duanchen Sun, William K Storck, Katherine Welker Leng, Chelsea Jenkins, Mark P Labrecque

Clin Cancer Res· September 2021

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RNA Splicing Factors SRRM3 and SRRM4 Distinguish Molecular Phenotypes of Castration-Resistant Neuroendocrine Prostate Cancer.
Mark P Labrecque, Lisha G Brown, Ilsa M Coleman, Bryce Lakely, Nicholas J Brady

Cancer Res· September 2021

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The heterogeneity of prostate cancers lacking AR activity will require diverse treatment approaches.
Mark P Labrecque, Joshi J Alumkal, Ilsa M Coleman, Peter S Nelson, Colm Morrissey

Endocr Relat Cancer· July 2021

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Cabozantinib can block growth of neuroendocrine prostate cancer patient-derived xenografts by disrupting tumor vasculature.
Mark P Labrecque, Lisha G Brown, Ilsa M Coleman, Holly M Nguyen, Daniel W Lin

PLoS One· June 2021

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Regulation of CEACAM5 and Therapeutic Efficacy of an Anti-CEACAM5-SN38 Antibody-drug Conjugate in Neuroendocrine Prostate Cancer.
Diana C DeLucia, Thomas M Cardillo, Lisa Ang, Mark P Labrecque, Ailin Zhang

Clin Cancer Res· February 2021

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Durable Response of Enzalutamide-resistant Prostate Cancer to Supraphysiological Testosterone Is Associated with a Multifaceted Growth Suppression and Impaired DNA Damage Response Transcriptomic Program in Patient-derived Xenografts.
Hung-Ming Lam, Holly M Nguyen, Mark P Labrecque, Lisha G Brown, Ilsa M Coleman

Eur Urol· February 2020

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Molecular profiling stratifies diverse phenotypes of treatment-refractory metastatic castration-resistant prostate cancer.
Mark P Labrecque, Ilsa M Coleman, Lisha G Brown, Lawrence D True, Lori Kollath

J Clin Invest· July 2019

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Expression of human inducible nitric oxide synthase in response to cytokines is regulated by hypoxia-inducible factor-1.
Martin Lee, Christine Wang, Steven W Jin, Mark P Labrecque, Timothy V Beischlag

Free Radic Biol Med· January 2019

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The retinoblastoma protein regulates hypoxia-inducible genetic programs, tumor cell invasiveness and neuroendocrine differentiation in prostate cancer cells.
Mark P Labrecque, Mandeep K Takhar, Rebecca Nason, Stephanie Santacruz, Kevin J Tam

Oncotarget· April 2016

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Epigenetic characterization of the growth hormone gene identifies SmcHD1 as a regulator of autosomal gene clusters.
Shabnam Massah, Robert Hollebakken, Mark P Labrecque, Addie M Kolybaba, Timothy V Beischlag

PLoS One· June 2015

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p,p'-Dichlorodiphenyltrichloroethane (p,p'-DDT) and p,p'-dichlorodiphenyldichloroethylene (p,p'-DDE) repress prostate specific antigen levels in human prostate cancer cell lines.
Lilian I L Wong, Mark P Labrecque, Naokazu Ibuki, Michael E Cox, John E Elliott

Chem Biol Interact· March 2015

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A TRIP230-retinoblastoma protein complex regulates hypoxia-inducible factor-1α-mediated transcription and cancer cell invasion.
Mark P Labrecque, Mandeep K Takhar, Julienne M Jagdeo, Kevin J Tam, Christina Chiu

PLoS One· February 2015

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Distinct roles for aryl hydrocarbon receptor nuclear translocator and ah receptor in estrogen-mediated signaling in human cancer cell lines.
Mark P Labrecque, Mandeep K Takhar, Brett D Hollingshead, Gratien G Prefontaine, Gary H Perdew

PLoS One· May 2012

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Estrogen receptor expression is required for low-dose resveratrol-mediated repression of aryl hydrocarbon receptor activity.
Gary H Perdew, Brett D Hollingshead, Brett C Dinatale, J Luis Morales, Mark P Labrecque

J Pharmacol Exp Ther· November 2010

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