Publications by authors named "Mark Pepin"

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A pilot study on DNA methylation changes for non-invasive molecular diagnostics in heart failure.
Giuditta Benincasa, Francesco Cacciatore, Mark E Pepin, Francesco Curcio, Rosaria Chiappetti

ESC Heart Fail· December 2025

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Metabo-epigenetic circuits of heart failure: chromatin-modifying enzymes as determinants of metabolic plasticity.
Mark E Pepin, Xuemin Gong, Almut Schulze, Johannes Backs

EMBO Mol Med· December 2025

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Dysregulated smooth muscle cell proliferation and gene expression underlie variant-associated aortopathy.
Mark E Pepin, Richard N Mitchell, Rajat M Gupta

Am J Physiol Heart Circ Physiol· November 2025

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Assessing the quality of AI-generated clinical notes: validated evaluation of a large language model ambient scribe.
Erin Palm, Astrit Manikantan, Herprit Mahal, Srikanth Subramanya Belwadi, Mark E Pepin

Front Artif Intell· November 2025

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DNA hypermethylation of MED1 and MED23 as early diagnostic biomarkers for unsolved issues in atrial fibrillation.
Concetta Schiano, Teresa Infante, Giuditta Benincasa, Jacopo Burrello, Antonio Ruocco, Mark E Pepin

Int J Cardiol· June 2025

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Proton dose calculation with transformer: Transforming spot map to dose.
Xueyan Tang, Hok Wan Chan Tseung, Mark D Pepin, Jed E Johnson, Doug J Moseley

Med Phys· June 2025

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Mitochondrial NNT Promotes Diastolic Dysfunction in Cardiometabolic HFpEF.
Mark E Pepin, Philipp J M Konrad, Sumra Nazir, Farhad Bazgir, Christoph Maack

Circ Res· June 2025

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High-resolution DNA methylation changes reveal biomarkers of heart failure with preserved ejection fraction versus reduced ejection fraction.
Giuditta Benincasa, Mark E Pepin, Vincenzo Russo, Francesco Cacciatore, Michele D'Alto

Basic Res Cardiol· April 2025

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Integrative analysis of single-cell transcriptomics and genetic associations identify cell states associated with vascular disease.
Mark E Pepin, William E Schwartzman, Shi Fang, Shamsudheen K Vellarikkal, Deepak S Atri

Atherosclerosis· April 2025

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Multicenter Multivendor Evaluation of Dose Volume Histogram Creation Consistencies for 8 Commercial Radiation Therapy Dosimetric Systems.
Gregory P Penoncello, Molly M Voss, Yu Gao, Levent Sensoy, Minsong Cao, Mark D Pepin

Pract Radiat Oncol· May 2024

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Radiation Dose Sensitivity of Subregions of the Larynx to Patient-Reported Swallowing Outcomes.
Mark D Pepin, Stephanie Anaya, Yolanda I Garces, Emily Hosfield, Scott C Lester

Adv Radiat Oncol· May 2024

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The Role of Endothelial Cells in Atherosclerosis: Insights from Genetic Association Studies.
Mark E Pepin, Rajat M Gupta

Am J Pathol· April 2024

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CDK5R1, GSE1, HSPG2 and WDFY3 as indirect epigenetic-sensitive genes in atrial fibrillation.
Teresa Infante, Mark E Pepin, Antonio Ruocco, Ugo Trama, Ciro Mauro

Eur J Clin Invest· March 2024

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A script-enabled interactive checklist document for efficient management of electronic devices in a busy multimodality radiotherapy clinic.
Mark D Pepin, Eric E Brost, Kristi A Klein, Yolanda I Garces, Debra H Brinkmann

J Appl Clin Med Phys· March 2024

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A network medicine approach to study comorbidities in heart failure with preserved ejection fraction.
Jan D Lanzer, Alberto Valdeolivas, Mark Pepin, Hauke Hund, Johannes Backs

BMC Med· July 2023

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Early Impact of Proton Beam Therapy on Electrophysiological Characteristics in a Porcine Model.
Kimitake Imamura, Amanda J Deisher, Jannis Dickow, Maryam E Rettmann, Omar Z Yasin, Mark D Pepin

Circ Arrhythm Electrophysiol· June 2023

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Indirect epigenetic testing identifies a diagnostic signature of cardiomyocyte DNA methylation in heart failure.
Christian U Oeing, Mark E Pepin, Kerstin B Saul, Ayça Seyhan Agircan, Yassen Assenov

Basic Res Cardiol· March 2023

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Deep phenotyping of two preclinical mouse models and a cohort of RBM20 mutation carriers reveals no sex-dependent disease severity in cardiomyopathy.
David C Lennermann, Mark E Pepin, Markus Grosch, Laura Konrad, Elena Kemmling

Am J Physiol Heart Circ Physiol· December 2022

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Assessment of dose-volume histogram precision for five clinical systems.
Mark D Pepin, Gregory P Penoncello, Kevin M Brom, Jon M Gustafson, Kenneth M Long

Med Phys· October 2022

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Fostering a diverse regional community of physician-scientist trainees.
Mark E Pepin, J Paige Souder, Alice N Weaver, Robin G Lorenz, Talene Yacoubian

J Natl Med Assoc· June 2022

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A novel curricular framework to develop grant writing skills among MD-PhD students.
Jaclyn P Souder, Mark E Pepin, Randy L Seay, Robin G Lorenz, William M Geisler

J Clin Transl Sci· April 2022

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A case of "smoldering" immune-mediated thrombotic thrombocytopenic purpura manifesting as recurrent cardioembolic stroke.
Mark E Pepin, Eyad Saca, Soo Y Kwon, Jori May

Clin Case Rep· October 2021

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Functional avoidance-based intensity modulated proton therapy with 4DCT derived ventilation imaging for lung cancer.
Jingjing M Dougherty, Edward Castillo, Richard Castillo, Austin M Faught, Mark Pepin

J Appl Clin Med Phys· July 2021

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Identification of Nrf2-responsive microRNA networks as putative mediators of myocardial reductive stress.
Justin M Quiles, Mark E Pepin, Sini Sunny, Sandeep B Shelar, Anil K Challa

Sci Rep· June 2021

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Racial and socioeconomic disparity associates with differences in cardiac DNA methylation among men with end-stage heart failure.
Mark E Pepin, Chae-Myeong Ha, Luke A Potter, Sayan Bakshi, Joseph P Barchue

Am J Physiol Heart Circ Physiol· May 2021

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