Publications by authors named "Mark Pines"

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Differential Effects of Halofuginone Enantiomers on Muscle Fibrosis and Histopathology in Duchenne Muscular Dystrophy.
Sharon Mordechay, Shaun Smullen, Paul Evans, Olga Genin, Mark Pines

Int J Mol Sci· June 2021

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Early pathological signs in young dysf mice are improved by halofuginone.
Hila Barzilai-Tutsch, Olga Genin, Mark Pines, Orna Halevy

Neuromuscul Disord· June 2020

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Hydroxy group requirement for halofuginone-dependent inhibition of muscle fibrosis and improvement of histopathology in the mdx mouse model for Duchenne muscular dystrophy.
Gili Wellner, Sharon Mordechay, Paul Evans, Olga Genin, Mark Pines

Histol Histopathol· July 2019

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A promotive effect for halofuginone on membrane repair and synaptotagmin-7 levels in muscle cells of dysferlin-null mice.
Hila Barzilai-Tutsch, Melissa Dewulf, Christophe Lamaze, Gillian Butler Browne, Mark Pines

Hum Mol Genet· August 2018

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Elevated Expression of Moesin in Muscular Dystrophies.
Mark Pines, Oshrat Levi, Olga Genin, Adi Lavy, Corrado Angelini

Am J Pathol· March 2017

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Strigolactone analogs act as new anti-cancer agents in inhibition of breast cancer in xenograft model.
Einav Mayzlish-Gati, Dana Laufer, Christopher F Grivas, Julia Shaknof, Amiram Sananes, Mark Pines

Cancer Biol Ther· September 2016

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Halofuginone promotes satellite cell activation and survival in muscular dystrophies.
Hila Barzilai-Tutsch, Anna Bodanovsky, Hadar Maimon, Mark Pines, Orna Halevy

Biochim Biophys Acta· January 2016

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Inhibition of muscle fibrosis results in increases in both utrophin levels and the number of revertant myofibers in Duchenne muscular dystrophy.
Oshrat Levi, Olga Genin, Corrado Angelini, Orna Halevy, Mark Pines

Oncotarget· September 2015

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The role of iNOS in cholesterol-induced liver fibrosis.
Sarit Anavi, Michal Eisenberg-Bord, Michal Hahn-Obercyger, Olga Genin, Mark Pines

Lab Invest· August 2015

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Halofuginone - the multifaceted molecule.
Mark Pines, Itai Spector

Molecules· January 2015

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Halofuginone for fibrosis, regeneration and cancer in the gastrointestinal tract.
Mark Pines

World J Gastroenterol· October 2014

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Halofuginone improves muscle-cell survival in muscular dystrophies.
Anna Bodanovsky, Noga Guttman, Hila Barzilai-Tutsch, Ola Genin, Oshrat Levy, Mark Pines

Biochim Biophys Acta· July 2014

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The chemistry and biology of febrifugine and halofuginone.
Noel P McLaughlin, Paul Evans, Mark Pines

Bioorg Med Chem· April 2014

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Involvement of host stroma cells and tissue fibrosis in pancreatic tumor development in transgenic mice.
Itai Spector, Yael Zilberstein, Adi Lavy, Arnon Nagler, Olga Genin, Mark Pines

PLoS One· April 2013

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The involvement of collagen triple helix repeat containing 1 in muscular dystrophies.
Itai Spector, Yael Zilberstein, Adi Lavy, Olga Genin, Hila Barzilai-Tutsch, Mark Pines

Am J Pathol· March 2013

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Inhibition of muscle fibrosis and improvement of muscle histopathology in dysferlin knock-out mice treated with halofuginone.
Orna Halevy, Olga Genin, Hila Barzilai-Tutsch, Yaniv Pima, Oshrat Levi, Mark Pines

Histol Histopathol· February 2013

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Halofuginone inhibits multiple myeloma growth in vitro and in vivo and enhances cytotoxicity of conventional and novel agents.
Merav Leiba, Jana Jakubikova, Steffen Klippel, Constantine S Mitsiades, Teru Hideshima, Mark Pines

Br J Haematol· June 2012

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Losartan reduces trinitrobenzene sulphonic acid-induced colorectal fibrosis in rats.
Dov Wengrower, Giuliana Zanninelli, Giovanni Latella, Stefano Necozione, Issa Metanes, Mark Pines

Can J Gastroenterol· January 2012

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Th17 cells and IL-17 in protective immunity to vaginal candidiasis.
Donatella Pietrella, Anna Rachini, Mark Pines, Neelam Pandey, Paolo Mosci

PLoS One· December 2011

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Hsp90 and angiogenesis in bone disorders--lessons from the avian growth plate.
Ayelet Herzog, Olga Genin, Ahron Hasdai, Dima Shinder, Mark Pines

Am J Physiol Regul Integr Comp Physiol· July 2011

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Halofuginone and muscular dystrophy.
Mark Pines, Orna Halevy

Histol Histopathol· January 2011

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Inhibition of pancreatic stellate cell activation by halofuginone prevents pancreatic xenograft tumor development.
Itai Spector, Hen Honig, Norifumi Kawada, Arnon Nagler, Olga Genin, Mark Pines

Pancreas· October 2010

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Fibrosis inhibition and muscle histopathology improvement in laminin-alpha2-deficient mice.
Yoram Nevo, Orna Halevy, Olga Genin, Itai Moshe, Tidhar Turgeman, Mark Pines

Muscle Nerve· August 2010

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Halofuginone inhibits Smad3 phosphorylation via the PI3K/Akt and MAPK/ERK pathways in muscle cells: effect on myotube fusion.
Suzy Roffe, Yosey Hagai, Mark Pines, Orna Halevy

Exp Cell Res· April 2010

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Inhibition of transforming growth factor beta signaling by halofuginone as a modality for pancreas fibrosis prevention.
Orit Zion, Olga Genin, Norifumi Kawada, Katsutoshi Yoshizato, Suzy Roffe, Mark Pines

Pancreas· May 2009

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