Publications by authors named "Mark Pook"

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A new FRDA mouse model [ :YG8s(GAA) > 800] with more than 800 GAA repeats.
Ester Kalef-Ezra, Fred Jonathan Edzeamey, Adamo Valle, Hassan Khonsari, Paula Kleine, Mark A Pook

Front Neurosci· January 2023

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Frataxin Deficit Leads to Reduced Dynamics of Growth Cones in Dorsal Root Ganglia Neurons of Friedreich's Ataxia YG8sR Model: A Multilinear Algebra Approach.
Diana C Muñoz-Lasso, Belén Mollá, Jhon J Sáenz-Gamboa, Edwin Insuasty, Maria de la Iglesia-Vaya, Mark A Pook

Front Mol Neurosci· June 2022

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A Drug Combination Rescues Frataxin-Dependent Neural and Cardiac Pathophysiology in FA Models.
Rosella Abeti, Mittal Jasoliya, Sahar Al-Mahdawi, Mark Pook, Cristina Gonzalez-Robles

Front Mol Biosci· May 2022

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DNA methylation in Friedreich ataxia silences expression of frataxin isoform E.
Layne N Rodden, Kaitlyn M Gilliam, Christina Lam, Teerapat Rojsajjakul, Clementina Mesaros, Mark Pook

Sci Rep· March 2022

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Interruptions of the GAA Repeat Tract Delay the Age at Onset of Friedreich's Ataxia in a Location Dependent Manner.
Suran Nethisinghe, Maheswaran Kesavan, Heather Ging, Robyn Labrum, James M Polke, Mark A Pook

Int J Mol Sci· July 2021

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HMTase Inhibitors as a Potential Epigenetic-Based Therapeutic Approach for Friedreich's Ataxia.
Mursal Sherzai, Adamo Valle, Nicholas Perry, Ester Kalef-Ezra, Sahar Al-Mahdawi, Mark Pook

Front Genet· June 2020

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Dimethyl fumarate dosing in humans increases frataxin expression: A potential therapy for Friedreich's Ataxia.
Mittal Jasoliya, Francesco Sacca, Sunil Sahdeo, Frederic Chedin, Chiara Pane, Mark Pook

PLoS One· February 2020

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The role of mitochondrial labile iron in Friedreich's ataxia skin fibroblasts sensitivity to ultraviolet A.
Olivier Reelfs, Vincenzo Abbate, Agostino Cilibrizzi, Mark A Pook, Robert C Hider

Metallomics· March 2019

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FAST-1 antisense RNA epigenetically alters FXN expression.
Hajar Mikaeili, Madhavi Sandi, Aurélien Bayot, Sahar Al-Mahdawi, Mark A Pook

Sci Rep· November 2018

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Large Interruptions of GAA Repeat Expansion Mutations in Friedreich Ataxia Are Very Rare.
Sahar Al-Mahdawi, Heather Ging, Aurelien Bayot, Francesca Cavalcanti, Valentina La Cognata, Mark A Pook

Front Cell Neurosci· November 2018

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Bone marrow transplantation stimulates neural repair in Friedreich's ataxia mice.
Kevin C Kemp, Kelly Hares, Juliana Redondo, Amelia J Cook, Harry R Haynes, Mark A Pook

Ann Neurol· April 2018

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Effect of diazoxide on Friedreich ataxia models.
Antonella Santoro, Sara Anjomani Virmouni, Eleonora Paradies, Valentina L Villalobos Coa, Sahar Al-Mahdawi, Mark A Pook

Hum Mol Genet· March 2018

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Cytokine therapy-mediated neuroprotection in a Friedreich's ataxia mouse model.
Kevin C Kemp, Nadia Cerminara, Kelly Hares, Juliana Redondo, Amelia J Cook, Mark Pook

Ann Neurol· February 2017

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FXN Promoter Silencing in the Humanized Mouse Model of Friedreich Ataxia.
Yogesh K Chutake, Whitney N Costello, Christina C Lam, Aniruddha C Parikh, Tamara T Hughes, Mark A Pook

PLoS One· June 2016

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Cellular, molecular and functional characterisation of YAC transgenic mouse models of Friedreich ataxia.
Sara Anjomani Virmouni, Chiranjeevi Sandi, Sahar Al-Mahdawi, Mark A Pook

PLoS One· December 2015

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Characterization of the retinal pigment epithelium in Friedreich ataxia.
Duncan E Crombie, Nicole Van Bergen, Kathryn C Davidson, Sara Anjomani Virmouni, Penny A Mckelvie, Mark A Pook

Biochem Biophys Rep· December 2015

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MutLα heterodimers modify the molecular phenotype of Friedreich ataxia.
Vahid Ezzatizadeh, Chiranjeevi Sandi, Madhavi Sandi, Sara Anjomani-Virmouni, Sahar Al-Mahdawi, Mark A Pook

PLoS One· October 2015

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Targeting lipid peroxidation and mitochondrial imbalance in Friedreich's ataxia.
Rosella Abeti, Ebru Uzun, Indhushri Renganathan, Tadashi Honda, Mark A Pook

Pharmacol Res· September 2015

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Identification of telomere dysfunction in Friedreich ataxia.
Sara Anjomani Virmouni, Sahar Al-Mahdawi, Chiranjeevi Sandi, Hemad Yasaei, Paola Giunti, Mark A Pook

Mol Neurodegener· June 2015

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A novel GAA-repeat-expansion-based mouse model of Friedreich's ataxia.
Sara Anjomani Virmouni, Vahid Ezzatizadeh, Chiranjeevi Sandi, Madhavi Sandi, Sahar Al-Mahdawi, Mark A Pook

Dis Model Mech· March 2015

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Frataxin deficiency increases cyclooxygenase 2 and prostaglandins in cell and animal models of Friedreich's ataxia.
Genki Hayashi, Yan Shen, Theresa L Pedersen, John W Newman, Mark Pook

Hum Mol Genet· December 2014

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Dyclonine rescues frataxin deficiency in animal models and buccal cells of patients with Friedreich's ataxia.
Sunil Sahdeo, Brian D Scott, Marissa Z McMackin, Mittal Jasoliya, Brandon Brown, Mark A Pook

Hum Mol Genet· December 2014

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The emerging role of 5-hydroxymethylcytosine in neurodegenerative diseases.
Sahar Al-Mahdawi, Sara Anjomani Virmouni, Mark A Pook

Front Neurosci· December 2014

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Generation and characterisation of Friedreich ataxia YG8R mouse fibroblast and neural stem cell models.
Chiranjeevi Sandi, Madhavi Sandi, Harvinder Jassal, Vahid Ezzatizadeh, Sara Anjomani-Virmouni, Mark A Pook

PLoS One· October 2014

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Epigenetic-based therapies for Friedreich ataxia.
Chiranjeevi Sandi, Madhavi Sandi, Sara Anjomani Virmouni, Sahar Al-Mahdawi, Mark A Pook

Front Genet· June 2014

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