Publications by authors named "Mark Schofield"

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The impacts of residence time and bed height on virus and aggregate clearance with a multimodal chromatography resin.
Mark Schofield, Christina Caporale, Kurt Boenning

J Chromatogr A· September 2025

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Membrane chromatography for AAV full capsid enrichment: Process development to scale up.
Julio Huato Hernandez, Kurt Boenning, Aydin Kavara, Mark Schofield

J Chromatogr B Analyt Technol Biomed Life Sci· August 2024

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Plutonium Hybrid Materials: A Platform to Explore Assembly and Metal-Ligand Bonding.
Robert G Surbella, Lucas C Ducati, Mark H Schofield, Bruce K McNamara, Kristi L Pellegrini

Inorg Chem· November 2022

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A novel symmetric pyrazine (pyz)-bridged uranyl dimer [UOCl(HO)(Pyz)]: synthesis, structure and computational analysis.
Nicole M Byrne, Mark H Schofield, Christopher L Cahill

Dalton Trans· July 2022

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Novel anion exchange membrane chromatography method for the separation of empty and full adeno-associated virus.
Adam L Hejmowski, Kurt Boenning, Julio Huato, Aydin Kavara, Mark Schofield

Biotechnol J· February 2022

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Pb-Oxo Interactions in Uranyl Hybrid Materials: A Combined Experimental and Computational Analysis of Bonding and Spectroscopic Properties.
Dominique M Brager, Aaron D Nicholas, Mark H Schofield, Christopher L Cahill

Inorg Chem· November 2021

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Bimetallic uranyl/cobalt(II) isothiocyanates: structure, property and spectroscopic analysis of homo- and heterometallic phases.
Nicole M Byrne, Mark H Schofield, Aaron D Nicholas, Christopher L Cahill

Dalton Trans· July 2021

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Validation and optimization of viral clearance in a downstream continuous chromatography setting.
Meng-Jung Chiang, Mark Pagkaliwangan, Scott Lute, Glen Bolton, Kurt Brorson, Mark Schofield

Biotechnol Bioeng· September 2019

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A Direct Approach for Process Development Using Single Column Experiments Results in Predictable Streamlined Multi-Column Chromatography Bioprocesses.
Aditya Utturkar, Keith Gillette, Chia-Yun Sun, Mark Pagkaliwangan, Rachel Quesenberry, Mark Schofield

Biotechnol J· April 2019

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Modeling the Downstream Processing of Monoclonal Antibodies Reveals Cost Advantages for Continuous Methods for a Broad Range of Manufacturing Scales.
Jonathan Hummel, Mark Pagkaliwangan, Xhorxhi Gjoka, Terence Davidovits, Rick Stock, Mark Schofield

Biotechnol J· February 2019

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Optimized Continuous Multicolumn Chromatography Enables Increased Productivities and Cost Savings by Employing More Columns.
Mark Pagkaliwangan, Jonathan Hummel, Xhorxhi Gjoka, Marc Bisschops, Mark Schofield

Biotechnol J· February 2019

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Current state of the art in continuous bioprocessing.
Mark Schofield

Biotechnol Lett· October 2018

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Transfer of a three step mAb chromatography process from batch to continuous: Optimizing productivity to minimize consumable requirements.
Xhorxhi Gjoka, Rene Gantier, Mark Schofield

J Biotechnol· January 2017

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A straightforward methodology for designing continuous monoclonal antibody capture multi-column chromatography processes.
Xhorxhi Gjoka, Karl Rogler, Richard Alexander Martino, Rene Gantier, Mark Schofield

J Chromatogr A· October 2015

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Combined Protein A and size exclusion high performance liquid chromatography for the single-step measurement of mAb, aggregates and host cell proteins.
Xhorxhi Gjoka, Mark Schofield, Aleksandar Cvetkovic, Rene Gantier

J Chromatogr B Analyt Technol Biomed Life Sci· December 2014

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Development of a tetrameric streptavidin mutein with reversible biotin binding capability: engineering a mobile loop as an exit door for biotin.
Valerie J O'Sullivan, Isabelle Barrette-Ng, Eric Hommema, Greg T Hermanson, Mark Schofield

PLoS One· August 2012

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TagA is a secreted protease of Vibrio cholerae that specifically cleaves mucin glycoproteins.
Rose L Szabady, Joseph H Yanta, David K Halladin, Mark J Schofield, Rodney A Welch

Microbiology (Reading)· February 2011

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Substituent effects on (15)N and (13)C NMR chemical shifts of 5-phenyl-1,3,4-oxathiazol-2-ones: a theoretical and spectroscopic study.
J Hodge Markgraf, Lu Hong, David P Richardson, Mark H Schofield

Magn Reson Chem· November 2007

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Substituent effects on 15N and 13C NMR chemical shifts of 3-phenylisoxazoles: a theoretical and spectroscopic study.
Mark H Schofield, Marie-Adele Sorel, Ryan J Manalansan, David P Richardson, J Hodge Markgraf

Magn Reson Chem· September 2006

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DNA mismatch repair: molecular mechanisms and biological function.
Mark J Schofield, Peggy Hsieh

Annu Rev Microbiol· February 2004

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DNA bending and unbending by MutS govern mismatch recognition and specificity.
Hong Wang, Yong Yang, Mark J Schofield, Chunwei Du, Yonatan Fridman

Proc Natl Acad Sci U S A· December 2003

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Formation of a DNA mismatch repair complex mediated by ATP.
Tassadite Selmane, Mark J Schofield, Sunil Nayak, Chunwei Du, Peggy Hsieh

J Mol Biol· December 2003

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Crystal structure and biochemical analysis of the MutS.ADP.beryllium fluoride complex suggests a conserved mechanism for ATP interactions in mismatch repair.
Eric Alani, Jae Young Lee, Mark J Schofield, Amanda W Kijas, Peggy Hsieh

J Biol Chem· May 2003

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