Publications by authors named "Mark Simpson"

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Capacity for Compensatory Cyclin D2 Response Confers Trametinib Resistance in Canine Mucosal Melanoma.
Bih-Rong Wei, Vincenzo Verdi, Shuling Zhang, Beverly A Mock, Heather R Shive, R Mark Simpson

Cancers (Basel)· July 2025

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Transitory Schwann Cell Precursor and hybrid states underpin melanoma therapy resistance and metastasis.
Vishaka Gopalan, Chun Wai Wong, Rotem Leshem, Luke Owen, Tuulia Vallius, R Mark Simpson

bioRxiv· July 2025

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Capacity for compensatory cyclin D2 response confers trametinib resistance in canine mucosal melanoma.
Bih-Rong Wei, Vincenzo Verdi, Shuling Zhang, Beverly A Mock, Heather R Shive, R Mark Simpson

bioRxiv· April 2025

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Reproducible preclinical models of androgen receptor driven human prostate cancer bone metastasis.
JuanJuan Yin, Asha Daryanani, Fan Lu, Anson T Ku, John R Bright, Mark Simpson

Prostate· August 2024

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Tongue orthotopic xenografts to study fusion-negative rhabdomyosarcoma invasion and metastasis in live animals.
Sarah M Hammoudeh, Yeap Ng, Bih-Rong Wei, Thomas D Madsen, Mukesh P Yadav, R Mark Simpson

Cell Rep Methods· July 2024

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Mitogenomic evidence of population differentiation of thorny skate, Amblyraja radiata, in the North Atlantic.
John S S Denton, Jeff Kneebone, Lei Yang, Arve Lynghammar, David McElroy, Mark Simpson

J Fish Biol· May 2024

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Agreement between the activPAL accelerometer and direct observation during a series of gait and sit-to-stand tasks in people living with cervical dystonia.
Irum Yaqoob, Silmara Gusso, Mark Simpson, Rebecca M Meiring

Front Neurol· April 2024

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Idiopathic membranous nephropathy and synchronous mononeuritis multiplex secondary to idiopathic small vessel vasculitis.
Kalpa Jayanatha, Ashutosh Kumar, Mark Sapsford, Mark Simpson

BMJ Case Rep· February 2024

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Fighting the Same Battles on a New Battleground: Embedding Technologies in a Virtual Care Environment.
Adeola Bamgboje-Ayodele, Adrian Boscolo, Owen Hutchings, Miranda Shaw, Mitchell Burger, Mark Simpson

Stud Health Technol Inform· January 2024

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How digital health translational research is prioritised: a qualitative stakeholder-driven approach to decision support evaluation.
Adeola Bamgboje-Ayodele, Steven M McPhail, David Brain, Richard Taggart, Mitchell Burger, Mark Simpson

BMJ Open· November 2023

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Fusion-negative rhabdomyosarcoma orthotopic tongue xenografts for study of invasion, intravasation and metastasis in live animals.
Sarah M Hammoudeh, Yeap Ng, Bih-Rong Wei, Thomas D Madsen, R Mark Simpson

bioRxiv· November 2023

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Drug combinations identified by high-throughput screening promote cell cycle transition and upregulate Smad pathways in myeloma.
Tyler J Peat, Snehal M Gaikwad, Wendy Dubois, Nana Gyabaah-Kessie, Shuling Zhang, R Mark Simpson

Cancer Lett· August 2023

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Yersinia pestis genomes reveal plague in Britain 4000 years ago.
Pooja Swali, Rick Schulting, Alexandre Gilardet, Monica Kelly, Kyriaki Anastasiadou, Mark Simpson

Nat Commun· May 2023

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Escape from oncogene-induced senescence is controlled by POU2F2 and memorized by chromatin scars.
Ricardo Iván Martínez-Zamudio, Alketa Stefa, José Américo Nabuco Leva Ferreira Freitas, Themistoklis Vasilopoulos, Mark Simpson

Cell Genom· April 2023

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Pharmacokinetics and tolerability of the dual TORC1/2 inhibitor sapanisertib in combination with the MEK inhibitor trametinib in dogs.
Bih-Rong Wei, Cody J Peer, William J Richardson, Stephen M Hewitt, William D Figg, R Mark Simpson

Front Vet Sci· December 2022

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Host CLIC4 expression in the tumor microenvironment is essential for breast cancer metastatic competence.
Vanesa C Sanchez, Howard H Yang, Alayna Craig-Lucas, Wendy Dubois, Brandi L Carofino, R Mark Simpson

PLoS Genet· June 2022

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CCL5 production in lung cancer cells leads to an altered immune microenvironment and promotes tumor development.
Etienne S Melese, Elizabeth Franks, Rachel A Cederberg, Bryant T Harbourne, Rocky Shi, R Mark Simpson

Oncoimmunology· April 2022

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Nuclear pore protein NUP210 depletion suppresses metastasis through heterochromatin-mediated disruption of tumor cell mechanical response.
Ruhul Amin, Anjali Shukla, Jacqueline Jufen Zhu, Sohyoung Kim, Ping Wang, R Mark Simpson

Nat Commun· December 2021

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Potential PINK1 Founder Effect in Polynesia Causing Early-Onset Parkinson's Disease.
Shilpan G Patel, Christina M Buchanan, Eoin Mulroy, Mark Simpson, Hannah A Reid

Mov Disord· September 2021

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International Guidelines for Veterinary Tumor Pathology: A Call to Action.
Donald J Meuten, Frances M Moore, Taryn A Donovan, Christof A Bertram, Robert Klopfleisch, R Mark Simpson

Vet Pathol· September 2021

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Telomeres and replicative cellular aging of the human placenta and chorioamniotic membranes.
Tsung-Po Lai, Mark Simpson, Krunal Patel, Simon Verhulst, Jungsik Noh

Sci Rep· March 2021

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A long-term follow-up of safety and clinical efficacy of NTCELL® [Immunoprotected (Alginate-encapsulated) porcine choroid plexus cells for xenotransplantation] in patients with Parkinson's disease.
Eoin Mulroy, Barry Snow, Arnold Bok, Mark Simpson, Andrew Smith

Parkinsonism Relat Disord· January 2021

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Efficacy, Tolerability, and Pharmacokinetics of Combined Targeted MEK and Dual mTORC1/2 Inhibition in a Preclinical Model of Mucosal Melanoma.
Bih-Rong Wei, Shelley B Hoover, Cody J Peer, Jennifer E Dwyer, Hibret A Adissu, R Mark Simpson

Mol Cancer Ther· November 2020

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Hypomorphic mTOR Downregulates CDK6 and Delays Thymic Pre-T LBL Tumorigenesis.
Joy M Gary, John K Simmons, Jinfei Xu, Shuling Zhang, Tyler J Peat, R Mark Simpson

Mol Cancer Ther· October 2020

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Inter-Institutional Partnerships to Develop Veterinarian-Investigators through the NIH Comparative Biomedical Scientist Training Program Benefit One Health Goals.
R Mark Simpson, Shelley B Hoover, Barbara J Davis, John Hickerson, Margaret A Miller

J Vet Med Educ· October 2020

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