Publications by authors named "Mark W Murphy"

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Diminished DNA binding affinity of DMRT1 caused by heterozygous DM domain mutations is a cause of male infertility.
Tihana Marić, Helen Castillo-Madeen, Monika Logara Klarić, Antun Barišić, Lovro Trgovec-Greif, Mark W Murphy

Hum Mol Genet· March 2025

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Genomics of sexual cell fate transdifferentiation in the mouse gonad.
Mark W Murphy, Micah D Gearhart, Andrew Wheeler, Vivian J Bardwell, David Zarkower

G3 (Bethesda)· December 2022

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DMRT1: An Ancient Sexual Regulator Required for Human Gonadogenesis.
David Zarkower, Mark W Murphy

Sex Dev· November 2022

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Lrh1 can help reprogram sexual cell fate and is required for Sertoli cell development and spermatogenesis in the mouse testis.
Kellie S Agrimson, Anna Minkina, Danielle Sadowski, Andrew Wheeler, Mark W Murphy

PLoS Genet· February 2022

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Author Correction: The NCI Genomic Data Commons.
Allison P Heath, Vincent Ferretti, Stuti Agrawal, Maksim An, James C Angelakos, Mark W Murphy

Nat Genet· June 2021

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The conserved sex regulator DMRT1 recruits SOX9 in sexual cell fate reprogramming.
Robin E Lindeman, Mark W Murphy, Kellie S Agrimson, Rachel L Gewiss, Vivian J Bardwell

Nucleic Acids Res· June 2021

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The NCI Genomic Data Commons.
Allison P Heath, Vincent Ferretti, Stuti Agrawal, Maksim An, James C Angelakos, Mark W Murphy

Nat Genet· March 2021

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Developing Cancer Informatics Applications and Tools Using the NCI Genomic Data Commons API.
Shane Wilson, Michael Fitzsimons, Martin Ferguson, Allison Heath, Mark Jensen, Mark W Murphy

Cancer Res· November 2017

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An ancient protein-DNA interaction underlying metazoan sex determination.
Mark W Murphy, John K Lee, Sandra Rojo, Micah D Gearhart, Kayo Kurahashi

Nat Struct Mol Biol· June 2015

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The mammalian Doublesex homolog DMRT6 coordinates the transition between mitotic and meiotic developmental programs during spermatogenesis.
Teng Zhang, Mark W Murphy, Micah D Gearhart, Vivian J Bardwell, David Zarkower

Development· October 2014

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Interaction between DMRT1 function and genetic background modulates signaling and pluripotency to control tumor susceptibility in the fetal germ line.
Anthony D Krentz, Mark W Murphy, Teng Zhang, Aaron L Sarver, Sanjay Jain

Dev Biol· May 2013

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DMRT1 promotes oogenesis by transcriptional activation of Stra8 in the mammalian fetal ovary.
Anthony D Krentz, Mark W Murphy, Aaron L Sarver, Michael D Griswold, Vivian J Bardwell

Dev Biol· August 2011

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DMRT1 prevents female reprogramming in the postnatal mammalian testis.
Clinton K Matson, Mark W Murphy, Aaron L Sarver, Michael D Griswold, Vivian J Bardwell

Nature· July 2011

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The mammalian doublesex homolog DMRT1 is a transcriptional gatekeeper that controls the mitosis versus meiosis decision in male germ cells.
Clinton K Matson, Mark W Murphy, Michael D Griswold, Shosei Yoshida, Vivian J Bardwell

Dev Cell· October 2010

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EGL-5/ABD-B plays an instructive role in male cell fate determination in the C. elegans somatic gonad.
Andrea K Kalis, Mark W Murphy, David Zarkower

Dev Biol· August 2010

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Genome-wide analysis of DNA binding and transcriptional regulation by the mammalian Doublesex homolog DMRT1 in the juvenile testis.
Mark W Murphy, Aaron L Sarver, Daren Rice, Katerina Hatzi, Kenny Ye

Proc Natl Acad Sci U S A· July 2010

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The DM domain protein DMRT1 is a dose-sensitive regulator of fetal germ cell proliferation and pluripotency.
Anthony D Krentz, Mark W Murphy, Shinseog Kim, Matthew S Cook, Blanche Capel

Proc Natl Acad Sci U S A· December 2009

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Vertebrate DM domain proteins bind similar DNA sequences and can heterodimerize on DNA.
Mark W Murphy, David Zarkower, Vivian J Bardwell

BMC Mol Biol· July 2007

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The DM domain protein MAB-3 promotes sex-specific neurogenesis in C. elegans by regulating bHLH proteins.
Jennifer M Ross, Andrea K Kalis, Mark W Murphy, David Zarkower

Dev Cell· June 2005

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The yeast splicing factor Prp40p contains functional leucine-rich nuclear export signals that are essential for splicing.
Mark W Murphy, Brian L Olson, Paul G Siliciano

Genetics· January 2004

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