Publications by authors named "Markus Jeschek"

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Of Revolutions and Roadblocks: The Emerging Role of Machine Learning in Biocatalysis.
Tobias Vornholt, Peter Stockinger, Mojmír Mutný, Markus Jeschek, Bettina Nestl

ACS Cent Sci· October 2025

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Computer-assisted multilevel optimization of malonyl-CoA availability in Pseudomonas putida.
Christos Batianis, Rik P van Rosmalen, Pedro Moñino Fernández, Konstantinos Labanaris, Enrique Asin-Garcia, Markus Jeschek

Metab Eng· July 2025

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Data-driven protease engineering by DNA-recording and epistasis-aware machine learning.
Lukas Huber, Tim Kucera, Simon Höllerer, Karsten Borgwardt, Sven Panke, Markus Jeschek

Nat Commun· July 2025

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Permeabilisation of the Outer Membrane of Escherichia coli for Enhanced Transport of Complex Molecules.
Ivan Casas-Rodrigo, Tobias Vornholt, Kathrin Castiglione, Tania Michelle Roberts, Markus Jeschek

Microb Biotechnol· March 2025

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Enhanced Sequence-Activity Mapping and Evolution of Artificial Metalloenzymes by Active Learning.
Tobias Vornholt, Mojmír Mutný, Gregor W Schmidt, Christian Schellhaas, Ryo Tachibana, Markus Jeschek

ACS Cent Sci· July 2024

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Ultradeep characterisation of translational sequence determinants refutes rare-codon hypothesis and unveils quadruplet base pairing of initiator tRNA and transcript.
Simon Höllerer, Markus Jeschek

Nucleic Acids Res· March 2023

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Systematic engineering of artificial metalloenzymes for new-to-nature reactions.
Tobias Vornholt, Fadri Christoffel, Michela M Pellizzoni, Sven Panke, Thomas R Ward, Markus Jeschek

Sci Adv· January 2021

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The Quest for Xenobiotic Enzymes: From New Enzymes for Chemistry to a Novel Chemistry of Life.
Tobias Vornholt, Markus Jeschek

Chembiochem· August 2020

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Large-scale DNA-based phenotypic recording and deep learning enable highly accurate sequence-function mapping.
Simon Höllerer, Laetitia Papaxanthos, Anja Cathrin Gumpinger, Katrin Fischer, Christian Beisel, Markus Jeschek

Nat Commun· July 2020

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Chemo-enzymatic cascades to produce cycloalkenes from bio-based resources.
Shuke Wu, Yi Zhou, Daniel Gerngross, Markus Jeschek, Thomas R Ward

Nat Commun· November 2019

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Correction: surface display of streptavidin for directed evolution of an allylic deallylase.
Tillmann Heinisch, Fabian Schwizer, Brett Garabedian, Eszter Csibra, Markus Jeschek

Chem Sci· July 2019

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surface display of streptavidin for directed evolution of an allylic deallylase.
Tillmann Heinisch, Fabian Schwizer, Brett Garabedian, Eszter Csibra, Markus Jeschek

Chem Sci· June 2018

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Artificial Metalloenzymes on the Verge of New-to-Nature Metabolism.
Markus Jeschek, Sven Panke, Thomas R Ward

Trends Biotechnol· January 2018

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Combinatorial pathway optimization for streamlined metabolic engineering.
Markus Jeschek, Daniel Gerngross, Sven Panke

Curr Opin Biotechnol· October 2017

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Biotin-independent strains of Escherichia coli for enhanced streptavidin production.
Markus Jeschek, Maximilian O Bahls, Veronika Schneider, Philippe Marlière, Thomas R Ward

Metab Eng· March 2017

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Directed evolution of artificial metalloenzymes for in vivo metathesis.
Markus Jeschek, Raphael Reuter, Tillmann Heinisch, Christian Trindler, Juliane Klehr

Nature· September 2016

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Rationally reduced libraries for combinatorial pathway optimization minimizing experimental effort.
Markus Jeschek, Daniel Gerngross, Sven Panke

Nat Commun· March 2016

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