Publications by authors named "Markus Leo"

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Targeting Astrocytic Connexin 43 Mitigates Glutamate-Driven Motor Neuron Stress in Late-Onset Spinal Muscular Atrophy.
Schahin Salmanian, Linda-Isabell Schmitt, Kai Christine Liebig, Stefanie Hezel, Andreas Roos, Markus Leo

Cells· November 2025

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Neuronal Pentraxin 2 as a Potential Biomarker for Nusinersen Therapy Response in Adults with Spinal Muscular Atrophy: A Pilot Study.
Svenja Neuhoff, Linda-Isabell Schmitt, Kai Christine Liebig, Stefanie Hezel, Nick Isana Tilahun, Markus Leo

Biomedicines· July 2025

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Results of the preclinical multicenter randomized controlled paclitaxel-induced neuropathy prevention replication study (PINPRICS).
Wolfgang Boehmerle, Tim Hagenacker, Markus Leo, Linda-Isabell Schmitt, Helmar C Lehmann

BMC Res Notes· April 2025

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Triiodothyronine treatment in mice improves stroke outcome and reduces blood-brain barrier damage.
Daniel Ullrich, Dagmar Führer, Heike Heuer, Steffen Mayerl, Steffen Haupeltshofer, Markus Leo

Eur Thyroid J· February 2025

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Thrombospondin-4 as potential cerebrospinal fluid biomarker for therapy response in pediatric spinal muscular atrophy.
Vera Dobelmann, Andreas Roos, Andreas Hentschel, Adela Della Marina, Markus Leo

J Neurol· October 2024

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Cell-mediated cytotoxicity within CSF and brain parenchyma in spinal muscular atrophy unaltered by nusinersen treatment.
I-Na Lu, Phyllis Fung-Yi Cheung, Michael Heming, Christian Thomas, Giovanni Giglio, Markus Leo

Nat Commun· May 2024

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Alteration of LARGE1 abundance in patients and a mouse model of 5q-associated spinal muscular atrophy.
Andreas Roos, Linda-Isabell Schmitt, Christina Hansmann, Stefanie Hezel, Schahin Salmanian, Markus Leo

Acta Neuropathol· March 2024

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Analysis of Free Circulating Messenger Ribonucleic Acids in Serum Samples from Late-Onset Spinal Muscular Atrophy Patients Using nCounter NanoString Technology.
Markus Leo, Linda-Isabell Schmitt, Fabian Mairinger, Andreas Roos, Christina Hansmann

Cells· September 2023

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Spinal astrocyte dysfunction drives motor neuron loss in late-onset spinal muscular atrophy.
Linda-Isabell Schmitt, Christina David, Rebecca Steffen, Stefanie Hezel, Andreas Roos, Markus Leo

Acta Neuropathol· May 2023

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Prevalence of Anti-Adeno-Associated Virus Serotype 9 Antibodies in Adult Patients with Spinal Muscular Atrophy.
Benjamin Stolte, Olivia Schreiber-Katz, René Günther, Claudia Diana Wurster, Susanne Petri, Markus Leo

Hum Gene Ther· September 2022

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Induction of Survival of Motor Neuron (SMN) Protein Deficiency in Spinal Astrocytes by Small Interfering RNA as an In Vitro Model of Spinal Muscular Atrophy.
Markus Leo, Linda-Isabell Schmitt, Michael Fleischer, Rebecca Steffen, Cora Osswald

Cells· February 2022

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Cisplatin-induced activation and functional modulation of satellite glial cells lead to cytokine-mediated modulation of sensory neuron excitability.
Markus Leo, Linda-Isabell Schmitt, Andrea Kutritz, Christoph Kleinschnitz, Tim Hagenacker

Exp Neurol· July 2021

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Modulation of Glutamate Transporter EAAT1 and Inward-Rectifier Potassium Channel K Expression in Cultured Spinal Cord Astrocytes by Platinum-Based Chemotherapeutics.
Markus Leo, Linda-Isabell Schmitt, Rebecca Steffen, Andrea Kutritz, Christoph Kleinschnitz

Int J Mol Sci· June 2021

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Platinum-Based Drugs Cause Mitochondrial Dysfunction in Cultured Dorsal Root Ganglion Neurons.
Markus Leo, Linda-Isabell Schmitt, Patricia Küsterarent, Andrea Kutritz, Tienush Rassaf

Int J Mol Sci· November 2020

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Compromised Hippocampal Neuroplasticity in the Interferon-α and Toll-like Receptor-3 Activation-Induced Mouse Depression Model.
Eduardo H Sanchez-Mendoza, Santiago Camblor-Perujo, Luiza Martins Nascentes-Melo, Egor Dzyubenko, Michael Fleischer, Markus Leo

Mol Neurobiol· July 2020

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Activation and functional modulation of satellite glial cells by oxaliplatin lead to hyperexcitability of sensory neurons in vitro.
Linda-Isabell Schmitt, Markus Leo, Andrea Kutritz, Christoph Kleinschnitz, Tim Hagenacker

Mol Cell Neurosci· June 2020

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Oxaliplatin Modulates the Characteristics of Voltage-Gated Calcium Channels and Action Potentials in Small Dorsal Root Ganglion Neurons of Rats.
Linda-Isabell Schmitt, Markus Leo, Christoph Kleinschnitz, Tim Hagenacker

Mol Neurobiol· December 2018

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Identification of Chaoborus kairomone chemicals that induce defences in Daphnia.
Linda C Weiss, Bauke Albada, Sina M Becker, Sven W Meckelmann, Julia Klein, Markus Leo

Nat Chem Biol· December 2018

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Cisplatin alters the function and expression of N-type voltage-gated calcium channels in the absence of morphological damage of sensory neurons.
Markus Leo, Linda-Isabell Schmitt, Holger Jastrow, Jürgen Thomale, Christoph Kleinschnitz

Mol Pain· July 2018

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Cisplatin-induced neuropathic pain is mediated by upregulation of N-type voltage-gated calcium channels in dorsal root ganglion neurons.
Markus Leo, Linda-Isabell Schmitt, Martin Erkel, Margarita Melnikova, Jürgen Thomale

Exp Neurol· February 2017

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7,8-Dihydroxyflavone leads to survival of cultured embryonic motoneurons by activating intracellular signaling pathways.
Teresa Tsai, Alice Klausmeyer, Rebecca Conrad, Christine Gottschling, Markus Leo

Mol Cell Neurosci· September 2013

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