Publications by authors named "Markus Thomas"

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Tumor Cell-Derived Angiopoietin-2 Promotes Metastasis in Melanoma.
Ashik Ahmed Abdul Pari, Mahak Singhal, Corinne Hübers, Carolin Mogler, Benjamin Schieb, Markus Thomas

Cancer Res· June 2020

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Anti-tumoral, anti-angiogenic and anti-metastatic efficacy of a tetravalent bispecific antibody (TAvi6) targeting VEGF-A and angiopoietin-2.
Werner Scheuer, Markus Thomas, Petra Hanke, Johannes Sam, Franz Osl

MAbs· December 2016

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Acute tumour response to a bispecific Ang-2-VEGF-A antibody: insights from multiparametric MRI and gene expression profiling.
Lauren C J Baker, Jessica K R Boult, Markus Thomas, Astrid Koehler, Tapan Nayak

Br J Cancer· September 2016

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Effect of Ang-2-VEGF-A Bispecific Antibody in Renal Cell Carcinoma.
Hideharu Bessho, Bernice Wong, Dachuan Huang, Jing Tan, Choon Kiat Ong, Markus Thomas

Cancer Invest· April 2016

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An integrated approach to quantitative modelling in angiogenesis research.
Anthony J Connor, Radosław P Nowak, Erica Lorenzon, Markus Thomas, Frank Herting

J R Soc Interface· September 2015

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Aggressive primary cutaneous B-cell lymphomas show increased Angiopoietin-2-induced angiogenesis.
Martin Teichert, Christine Stumpf, Nina Booken, Marion Wobser, Dorothee Nashan, Markus Thomas

Exp Dermatol· June 2015

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Angiogenesis in malignant melanoma.
Moritz Felcht, Markus Thomas

J Dtsch Dermatol Ges· February 2015

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Postsurgical adjuvant tumor therapy by combining anti-angiopoietin-2 and metronomic chemotherapy limits metastatic growth.
Kshitij Srivastava, Junhao Hu, Claudia Korn, Soniya Savant, Martin Teichert, Markus Thomas

Cancer Cell· December 2014

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Angiopoietin-2 is critical for cytokine-induced vascular leakage.
Andrew V Benest, Karoline Kruse, Soniya Savant, Markus Thomas, Anna M Laib

PLoS One· March 2014

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Progress in overcoming the chain association issue in bispecific heterodimeric IgG antibodies.
Christian Klein, Claudio Sustmann, Markus Thomas, Kay Stubenrauch, Rebecca Croasdale

MAbs· January 2014

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Endothelial cell-derived angiopoietin-2 controls liver regeneration as a spatiotemporal rheostat.
Junhao Hu, Kshitij Srivastava, Matthias Wieland, Anja Runge, Carolin Mogler, Markus Thomas

Science· January 2014

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A novel angiopoietin-2 selective fully human antibody with potent anti-tumoral and anti-angiogenic efficacy and superior side effect profile compared to Pan-Angiopoietin-1/-2 inhibitors.
Markus Thomas, Yvonne Kienast, Werner Scheuer, Monika Bähner, Klaus Kaluza

PLoS One· December 2013

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Ang-2-VEGF-A CrossMab, a novel bispecific human IgG1 antibody blocking VEGF-A and Ang-2 functions simultaneously, mediates potent antitumor, antiangiogenic, and antimetastatic efficacy.
Yvonne Kienast, Christian Klein, Werner Scheuer, Romi Raemsch, Erica Lorenzon, Markus Thomas

Clin Cancer Res· December 2013

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Crystal structure of an anti-Ang2 CrossFab demonstrates complete structural and functional integrity of the variable domain.
Sebastian Fenn, Christian B Schiller, Julia J Griese, Harald Duerr, Sabine Imhof-Jung, Joerg Thomas Regula, Markus Thomas

PLoS One· November 2013

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Angiopoietin 2 mediates microvascular and hemodynamic alterations in sepsis.
Tilman Ziegler, Jan Horstkotte, Claudia Schwab, Vanessa Pfetsch, Karolina Weinmann, Markus Thomas

J Clin Invest· July 2013

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Established breast cancer stem cell markers do not correlate with in vivo tumorigenicity of tumor-initiating cells.
Christian Lehmann, Gabriele Jobs, Markus Thomas, Helmut Burtscher, Manfred Kubbies

Int J Oncol· December 2012

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Anaerobic metabolism of indoleacetate.
Christa Ebenau-Jehle, Markus Thomas, Gernot Scharf, Daniel Kockelkorn, Bettina Knapp

J Bacteriol· June 2012

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Angiopoietin-2 differentially regulates angiogenesis through TIE2 and integrin signaling.
Moritz Felcht, Robert Luck, Alexander Schering, Philipp Seidel, Kshitij Srivastava, Thomas Wieland, Markus Thomas

J Clin Invest· June 2012

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A human neutralizing antibody specific to Ang-2 inhibits ocular angiogenesis.
Emma S Rennel, Jörg T Regula, Steven J Harper, Markus Thomas, Christian Klein

Microcirculation· October 2011

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Immunoglobulin domain crossover as a generic approach for the production of bispecific IgG antibodies.
Wolfgang Schaefer, Jörg T Regula, Monika Bähner, Jürgen Schanzer, Rebecca Croasdale, Markus Thomas

Proc Natl Acad Sci U S A· July 2011

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Angiopoietin-2 stimulation of endothelial cells induces alphavbeta3 integrin internalization and degradation.
Markus Thomas, Moritz Felcht, Karoline Kruse, Stella Kretschmer, Carleen Deppermann

J Biol Chem· July 2010

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The role of the Angiopoietins in vascular morphogenesis.
Markus Thomas, Hellmut G Augustin

Angiogenesis· August 2009

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Host-derived angiopoietin-2 affects early stages of tumor development and vessel maturation but is dispensable for later stages of tumor growth.
Patrick Nasarre, Markus Thomas, Karoline Kruse, Iris Helfrich, Vivien Wolter

Cancer Res· February 2009

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Angiopoietin-2 levels are associated with disease progression in metastatic malignant melanoma.
Iris Helfrich, Lutz Edler, Antje Sucker, Markus Thomas, Sven Christian

Clin Cancer Res· February 2009

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