Publications by authors named "Marlene Jimenez-Del-Rio"

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Presenilin 1 E280A mutation induces dysfunctional astrocytic phenotype in menstrual stromal-derived astrocyte-like cells.
Natalia Quiroz Correa, Miguel Mendivil-Perez, Carlos Velez-Pardo, Marlene Jimenez-Del-Rio, Q Quiroz-Correa

Cell Mol Life Sci· October 2025

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Induced Microglial-like Cells Derived from Familial and Sporadic Alzheimer's Disease Peripheral Blood Monocytes Show Abnormal Phagocytosis and Inflammatory Response to PSEN1 E280A Cholinergic-like Neurons.
Viviana Soto-Mercado, Miguel Mendivil-Perez, Carlos Velez-Pardo, Marlene Jimenez-Del-Rio

Int J Mol Sci· July 2025

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Sex differences in the diagnosis latency of Parkinson's disease in Latin America.
Janvi Ramchandra, Miguel Inca-Martinez, Thiago Peixoto Leal, Henry Mauricio Chaparro-Solano, Amira Salim

Parkinsonism Relat Disord· May 2025

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PF-06447475 Molecule Attenuates the Neuropathology of Familial Alzheimer's and Coexistent Parkinson's Disease Markers in PSEN1 I416T Dopaminergic-like Neurons.
Diana Alejandra Quintero-Espinosa, Carlos Velez-Pardo, Marlene Jimenez-Del-Rio

Molecules· May 2025

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Protective Effect of the LRRK2 Kinase Inhibition in Human Fibroblasts Bearing the Genetic Variant GBA1 K198E: Implications for Parkinson's Disease.
Laura Patricia Perez-Abshana, Miguel Mendivil-Perez, Carlos Velez-Pardo, Marlene Jimenez-Del-Rio

Neuromolecular Med· May 2025

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Combination of Epigallocatechin-3-Gallate and Tramiprosate Prevent Accumulation of Intracellular Aβ and Dysfunctional Autophagy-Lysosomal Pathway at Earliest Stage of Transdifferentiation of Mesenchymal Stromal Cells into PSEN1 E280A Cholinergic-like Neurons.
Viviana Soto-Mercado, Miguel Mendivil-Perez, Marlene Jimenez-Del-Rio, Carlos Velez-Pardo

Int J Mol Sci· April 2025

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Minocycline mitigates Aβ and TAU pathology, neuronal dysfunction, and death in the PSEN1 E280A cholinergic-like neurons model of familial Alzheimer's disease.
Daniela Giraldo-Berrio, Marlene Jimenez-Del-Rio, Carlos Velez-Pardo

Neuropharmacology· December 2024

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Parkinson's Disease Gene Screening in Familial Cases from Central and South America.
Oswaldo Lorenzo-Betancor, Seysha Mehta, Janvi Ramchandra, Sekinat Mumuney, Artur F Schumacher-Schuh, Marlene Jimenez-Del-Rio

Mov Disord· October 2024

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The Antiproteinopathy, Antioxidant, and Antiapoptotic Effects of Methylene Blue and 4-Phenylbutyric Acid Alone, and in Combination on Familial Alzheimer's Disease PSEN1 I416T Cholinergic-Like Neurons.
Nicolas Gomez-Sequeda, Marlene Jimenez-Del-Rio, Carlos Velez-Pardo

ACS Chem Neurosci· October 2024

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LRRK2 Kinase Inhibitor PF-06447475 Protects Drosophila melanogaster against Paraquat-Induced Locomotor Impairment, Life Span Reduction, and Oxidative Stress.
Diana A Quintero-Espinosa, Marlene Jimenez-Del-Rio, Carlos Velez-Pardo

Neurochem Res· September 2024

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The GBA1 K198E Variant Is Associated with Suppression of Glucocerebrosidase Activity, Autophagy Impairment, Oxidative Stress, Mitochondrial Damage, and Apoptosis in Skin Fibroblasts.
Laura Patricia Perez-Abshana, Miguel Mendivil-Perez, Marlene Jimenez-Del-Rio, Carlos Velez-Pardo

Int J Mol Sci· August 2024

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Rotenone Induces a Neuropathological Phenotype in Cholinergic-like Neurons Resembling Parkinson's Disease Dementia (PDD).
Daniela Giraldo-Berrio, Miguel Mendivil-Perez, Carlos Velez-Pardo, Marlene Jimenez-Del-Rio

Neurotox Res· June 2024

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Sildenafil Reverses the Neuropathological Alzheimer's Disease Phenotype in Cholinergic-Like Neurons Carrying the Presenilin 1 E280A Mutation.
Daniela Giraldo-Berrio, Marlene Jimenez-Del-Rio, Carlos Velez-Pardo

J Alzheimers Dis· May 2024

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Neuroprotective Effect of Combined Treatment with Epigallocatechin 3-Gallate and Melatonin on Familial Alzheimer's Disease PSEN1 E280A Cerebral Spheroids Derived from Menstrual Mesenchymal Stromal Cells.
Viviana Soto-Mercado, Miguel Mendivil-Perez, Carlos Velez-Pardo, Marlene Jimenez-Del-Rio

J Alzheimers Dis· April 2024

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Combination of Tramiprosate, Curcumin, and SP600125 Reduces the Neuropathological Phenotype in Familial Alzheimer Disease PSEN1 I416T Cholinergic-like Neurons.
Nicolas Gomez-Sequeda, Marlene Jimenez-Del-Rio, Carlos Velez-Pardo

Int J Mol Sci· April 2024

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Christchurch modulates β-catenin/Wnt signaling in iPS cell-derived cerebral organoids from Alzheimer's cases.
Paula Perez-Corredor, Timothy E Vanderleest, Guido N Vacano, Justin S Sanchez, Nelson D Villalba-Moreno

Front Mol Neurosci· March 2024

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High Yield of Functional Dopamine-like Neurons Obtained in NeuroForsk 2.0 Medium to Study Acute and Chronic Rotenone Effects on Oxidative Stress, Autophagy, and Apoptosis.
Diana Alejandra Quintero-Espinosa, Carlos Velez-Pardo, Marlene Jimenez-Del-Rio

Int J Mol Sci· October 2023

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X-Chromosome Association Study in Latin American Cohorts Identifies New Loci in Parkinson's Disease.
Thiago P Leal, Shilpa C Rao, Jennifer N French-Kwawu, Mateus H Gouveia, Victor Borda, Marlene Jimenez-Del-Rio

Mov Disord· September 2023

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Cholinergic-like neurons and cerebral spheroids bearing the PSEN1 p.Ile416Thr variant mirror Alzheimer's disease neuropathology.
Nicolas Gomez-Sequeda, Miguel Mendivil-Perez, Marlene Jimenez-Del-Rio, Francisco Lopera, Carlos Velez-Pardo

Sci Rep· August 2023

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Cannabidiol Protects Dopaminergic-like Neurons against Paraquat- and Maneb-Induced Cell Death through Safeguarding DJ-1CYS and Caspase 3 Independently of Cannabinoid Receptors: Relevance in Parkinson's Disease.
Miguel Mendivil-Perez, Andrea A Felizardo-Otalvaro, Marlene Jimenez-Del-Rio, Carlos Velez-Pardo

ACS Chem Neurosci· June 2023

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LRRK2 Knockout Confers Resistance in HEK-293 Cells to Rotenone-Induced Oxidative Stress, Mitochondrial Damage, and Apoptosis.
Diana Alejandra Quintero-Espinosa, Sabina Sanchez-Hernandez, Carlos Velez-Pardo, Francisco Martin, Marlene Jimenez-Del-Rio

Int J Mol Sci· June 2023

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Rotenone Blocks the Glucocerebrosidase Enzyme and Induces the Accumulation of Lysosomes and Autophagolysosomes Independently of LRRK2 Kinase in HEK-293 Cells.
Laura Patricia Perez-Abshana, Miguel Mendivil-Perez, Carlos Velez-Pardo, Marlene Jimenez-Del-Rio

Int J Mol Sci· June 2023

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PSEN1 E280A Cholinergic-like Neurons and Cerebral Spheroids Derived from Mesenchymal Stromal Cells and from Induced Pluripotent Stem Cells Are Neuropathologically Equivalent.
Miguel Mendivil-Perez, Carlos Velez-Pardo, Francisco Lopera, Kenneth S Kosik, Marlene Jimenez-Del-Rio

Int J Mol Sci· May 2023

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X-Chromosome Association Study in Latin American Cohorts Identifies New Loci in Parkinson Disease.
Thiago P Leal, Jennifer N French-Kwawu, Mateus H Gouveia, Victor Borda, Miguel Inca-Martinez, Marlene Jimenez-Del-Rio

medRxiv· February 2023

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TPEN/TPGS (T2) combo dramatically reduces Philadelphia chromosome-positive pro-lymphoblastic B leukemia in BALB/c mice.
Miguel Mendivil-Perez, Marlene Jimenez-Del-Rio, Carlos Velez-Pardo

Med Oncol· November 2022

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