Publications by authors named "Marouan Rami"

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Functionalized nitrogen- and chalcogen-containing heterocyclic compounds as aromatase inhibitors: Design, synthesis and biological evaluation.
Chang Ha Park, Marc Le Borgne, Marouan Rami, Martin Fossart, Patricia Melnyk

Eur J Med Chem· January 2026

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(Hetero)aryl substituted thiazol-2,4-yl scaffold as human carbonic anhydrase I, II, VII and XIV activators.
Marouan Rami, Jean-Yves Winum, Claudiu T Supuran, Patricia Melnyk, Saïd Yous

J Enzyme Inhib Med Chem· December 2019

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Synthesis and biological evaluation of new naphtho- and quinolinocyclopentane derivatives as potent melatoninergic (MT/MT) and serotoninergic (5-HT) dual ligands.
Romain Duroux, Marouan Rami, Elodie Landagaray, Mohamed Ettaoussi, Daniel-Henri Caignard

Eur J Med Chem· December 2017

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New quinolinic derivatives as melatonergic ligands: Synthesis and pharmacological evaluation.
Elodie Landagaray, Mohamed Ettaoussi, Marouan Rami, Jean A Boutin, Daniel-Henri Caignard

Eur J Med Chem· February 2017

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Hypoxia-targeting carbonic anhydrase IX inhibitors by a new series of nitroimidazole-sulfonamides/sulfamides/sulfamates.
Marouan Rami, Ludwig Dubois, Nanda-Kumar Parvathaneni, Vincenzo Alterio, Simon J A van Kuijk

J Med Chem· November 2013

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Targeting carbonic anhydrase IX by nitroimidazole based sulfamides enhances the therapeutic effect of tumor irradiation: a new concept of dual targeting drugs.
Ludwig Dubois, Sarah G J A Peeters, Simon J A van Kuijk, Ala Yaromina, Natasja G Lieuwes, Marouan Rami

Radiother Oncol· September 2013

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Novel conformationally constrained analogues of agomelatine as new melatoninergic ligands.
Marouan Rami, Elodie Landagaray, Mohamed Ettaoussi, Koussayla Boukhalfa, Daniel-Henri Caignard

Molecules· December 2012

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Design, synthesis and pharmacological evaluation of new series of naphthalenic analogues as melatoninergic (MT1/MT2) and serotoninergic 5-HT2C dual ligands (I).
Mohamed Ettaoussi, Ahmed Sabaouni, Marouan Rami, Jean A Boutin, Philippe Delagrange

Eur J Med Chem· March 2012

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Synthesis of rhodamine B-benzenesulfonamide conjugates and their inhibitory activity against human α- and bacterial/fungal β-carbonic anhydrases.
Marouan Rami, Alessio Innocenti, Jean-Louis Montero, Andrea Scozzafava, Jean-Yves Winum

Bioorg Med Chem Lett· September 2011

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Design and synthesis of naphthalenic derivatives as new ligands at the melatonin binding site MT3.
Véronique Leclerc, Mohamed Ettaoussi, Marouan Rami, Amaury Farce, Jean Albert Boutin

Eur J Med Chem· May 2011

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Sulfonamides incorporating boroxazolidone moieties are potent inhibitors of the transmembrane, tumor-associated carbonic anhydrase isoforms IX and XII.
Marouan Rami, Alfonso Maresca, Fatma-Zhora Smaine, Jean-Louis Montero, Andrea Scozzafava

Bioorg Med Chem Lett· May 2011

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Carbonic anhydrase inhibitor coated gold nanoparticles selectively inhibit the tumor-associated isoform IX over the cytosolic isozymes I and II.
Maamar Stiti, Alessandro Cecchi, Marouan Rami, Mohamed Abdaoui, Véronique Barragan-Montero

J Am Chem Soc· December 2008

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Carbonic anhydrase inhibitors: 2-substituted-1,3,4-thiadiazole-5-sulfamides act as powerful and selective inhibitors of the mitochondrial isozymes VA and VB over the cytosolic and membrane-associated carbonic anhydrases I, II and IV.
Fatma-Zohra Smaine, Fabio Pacchiano, Marouan Rami, Véronique Barragan-Montero, Daniela Vullo

Bioorg Med Chem Lett· December 2008

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Carbonic anhydrase inhibitors: design of membrane-impermeant copper(II) complexes of DTPA-, DOTA-, and TETA-tailed sulfonamides targeting the tumor-associated transmembrane isoform IX.
Marouan Rami, Alessandro Cecchi, Jean-Louis Montero, Alessio Innocenti, Daniela Vullo

ChemMedChem· November 2008

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Carbonic anhydrase IX: a new druggable target for the design of antitumor agents.
Jean-Yves Winum, Marouan Rami, Andrea Scozzafava, Jean-Louis Montero, Claudiu Supuran

Med Res Rev· May 2008

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Carbonic anhydrase inhibitors: copper(II) complexes of polyamino-polycarboxylamido aromatic/heterocyclic sulfonamides are very potent inhibitors of the tumor-associated isoforms IX and XII.
Marouan Rami, Jean-Yves Winum, Alessio Innocenti, Jean-Louis Montero, Andrea Scozzafava

Bioorg Med Chem Lett· January 2008

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