Publications by authors named "Martin A Graham"

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Development and verification of a pharmacokinetic model to optimize physiologic replacement of rhIGF-1/rhIGFBP-3 in preterm infants.
Jou-Ku Chung, Boubou Hallberg, Ingrid Hansen-Pupp, Martin A Graham, Gerald Fetterly

Pediatr Res· March 2017

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A Phase I Study of the SMAC-Mimetic Birinapant in Adults with Refractory Solid Tumors or Lymphoma.
Ravi K Amaravadi, Russell J Schilder, Lainie P Martin, Myron Levin, Martin A Graham

Mol Cancer Ther· November 2015

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Birinapant, a smac-mimetic with improved tolerability for the treatment of solid tumors and hematological malignancies.
Stephen M Condon, Yasuhiro Mitsuuchi, Yijun Deng, Matthew G LaPorte, Susan R Rippin, Martin A Graham

J Med Chem· May 2014

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Birinapant (TL32711), a bivalent SMAC mimetic, targets TRAF2-associated cIAPs, abrogates TNF-induced NF-κB activation, and is active in patient-derived xenograft models.
Christopher A Benetatos, Yasuhiro Mitsuuchi, Jennifer M Burns, Eric M Neiman, Stephen M Condon, Martin A Graham

Mol Cancer Ther· April 2014

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Temporal and spatial evolution of therapy-induced tumor apoptosis detected by caspase-3-selective molecular imaging.
Quang-Dé Nguyen, Ioannis Lavdas, James Gubbins, Graham Smith, Robin Fortt, Martin A Graham

Clin Cancer Res· July 2013

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Oxaliplatin pharmacokinetics and pharmacodynamics in adult cancer patients with impaired renal function.
Chris H Takimoto, Martin A Graham, Graham Lockwood, Chee M Ng, Andrew Goetz

Clin Cancer Res· August 2007

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A phase 1, double-blind, placebo-controlled study evaluating single subcutaneous administrations of a human interleukin-12/23 monoclonal antibody in subjects with plaque psoriasis.
Alice B Gottlieb, Kevin D Cooper, Thomas S McCormick, Eiko Toichi, Daniel E Everitt, Martin A Graham

Curr Med Res Opin· May 2007

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A phase I study assessing the safety, clinical response, and pharmacokinetics of an experimental infliximab formulation for subcutaneous or intramuscular administration in patients with rheumatoid arthritis.
René Westhovens, Frédéric Houssiau, Johan Joly, Daniel E Everitt, Yaowei Zhu, Martin A Graham

J Rheumatol· May 2006

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Absence of adverse effects in cynomolgus macaques treated with CNTO 95, a fully human anti-alphav integrin monoclonal antibody, despite widespread tissue binding.
Pauline L Martin, Qun Jiao, Joel Cornacoff, William Hall, Bradley Saville, Martin A Graham

Clin Cancer Res· October 2005

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Formation, distribution, and elimination of infliximab and anti-infliximab immune complexes in cynomolgus monkeys.
Jeannie R Rojas, Ronald P Taylor, Mark R Cunningham, Thomas J Rutkoski, Joseph Vennarini, Martin A Graham

J Pharmacol Exp Ther· May 2005

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A phase I study evaluating the safety, pharmacokinetics, and clinical response of a human IL-12 p40 antibody in subjects with plaque psoriasis.
Catharine L Kauffman, Nancy Aria, Eiko Toichi, Thomas S McCormick, Kevin D Cooper, Martin A Graham

J Invest Dermatol· December 2004

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Oxaliplatin: a review of evolving concepts.
Sridhar Mani, Martin A Graham, David B Bregman, Percy Ivy, Stephen G Chaney

Cancer Invest· May 2002

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