Publications by authors named "Martin F Semmelhack"

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Antibiotic Adjuvant Activity Revealed in a Photoaffinity Approach to Determine the Molecular Target of Antipyocyanin Compounds.
Zinan Zhang, Dominic Ortega, Anthony Rush, Lauren R Blankenship, Zi Jun Cheng, Martin F Semmelhack

ACS Infect Dis· March 2021

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Structure, Regulation, and Inhibition of the Quorum-Sensing Signal Integrator LuxO.
Hande Boyaci, Tayyab Shah, Amanda Hurley, Bashkim Kokona, Zhijie Li, Martin F Semmelhack

PLoS Biol· May 2016

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Modulating Vibrio cholerae quorum-sensing-controlled communication using autoinducer-loaded nanoparticles.
Hoang D Lu, Alina C Spiegel, Amanda Hurley, Lark J Perez, Katharina Maisel, Martin F Semmelhack

Nano Lett· April 2015

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Development of potent inhibitors of pyocyanin production in Pseudomonas aeruginosa.
Laura C Miller, Colleen T O'Loughlin, Zinan Zhang, Albert Siryaporn, Justin E Silpe, Martin F Semmelhack

J Med Chem· February 2015

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Caenorhabditis elegans recognizes a bacterial quorum-sensing signal molecule through the AWCON neuron.
Kristen M Werner, Lark J Perez, Rajarshi Ghosh, Martin F Semmelhack, Bonnie L Bassler

J Biol Chem· September 2014

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Synthesis and biological evaluation of bis-CNB-GABA, a photoactivatable neurotransmitter with low receptor interference and chemical two-photon uncaging properties.
Diana D Shi, Federico F Trigo, Martin F Semmelhack, Samuel S-H Wang

J Am Chem Soc· February 2014

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Highly Potent, Chemically Stable Quorum Sensing Agonists for .
Lark J Perez, Theodora K Karagounis, Amanda Hurley, Bonnie L Bassler, Martin F Semmelhack

Chem Sci· January 2014

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A quorum-sensing inhibitor blocks Pseudomonas aeruginosa virulence and biofilm formation.
Colleen T O'Loughlin, Laura C Miller, Albert Siryaporn, Knut Drescher, Martin F Semmelhack

Proc Natl Acad Sci U S A· October 2013

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Broad spectrum pro-quorum-sensing molecules as inhibitors of virulence in vibrios.
Wai-Leung Ng, Lark Perez, Jianping Cong, Martin F Semmelhack, Bonnie L Bassler

PLoS Pathog· November 2012

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Role of the CAI-1 fatty acid tail in the Vibrio cholerae quorum sensing response.
Lark J Perez, Wai-Leung Ng, Paul Marano, Karolina Brook, Bonnie L Bassler, Martin F Semmelhack

J Med Chem· November 2012

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Identification of small molecules that antagonize diguanylate cyclase enzymes to inhibit biofilm formation.
Karthik Sambanthamoorthy, Rudolph E Sloup, Vijay Parashar, Joshua M Smith, Eric E Kim, Martin F Semmelhack

Antimicrob Agents Chemother· October 2012

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Small molecule probes of the receptor binding site in the Vibrio cholerae CAI-1 quorum sensing circuit.
Megan E Bolitho, Lark J Perez, Matthew J Koch, Wai-Leung Ng, Bonnie L Bassler, Martin F Semmelhack

Bioorg Med Chem· November 2011

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Identification of a novel benzimidazole that inhibits bacterial biofilm formation in a broad-spectrum manner.
Karthik Sambanthamoorthy, Ankush A Gokhale, Weiwei Lao, Vijay Parashar, Matthew B Neiditch, Martin F Semmelhack

Antimicrob Agents Chemother· September 2011

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Processing the interspecies quorum-sensing signal autoinducer-2 (AI-2): characterization of phospho-(S)-4,5-dihydroxy-2,3-pentanedione isomerization by LsrG protein.
João C Marques, Pedro Lamosa, Caitlin Russell, Rita Ventura, Christopher Maycock, Martin F Semmelhack

J Biol Chem· May 2011

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Mechanism of Vibrio cholerae autoinducer-1 biosynthesis.
Yunzhou Wei, Lark J Perez, Wai-Leung Ng, Martin F Semmelhack, Bonnie L Bassler

ACS Chem Biol· April 2011

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The free and bound forms of Lpp occupy distinct subcellular locations in Escherichia coli.
Charles E Cowles, Yongfeng Li, Martin F Semmelhack, Ileana M Cristea, Thomas J Silhavy

Mol Microbiol· March 2011

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Signal production and detection specificity in Vibrio CqsA/CqsS quorum-sensing systems.
Wai-Leung Ng, Lark J Perez, Yunzhou Wei, Christina Kraml, Martin F Semmelhack

Mol Microbiol· March 2011

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The structural basis for tight control of PP2A methylation and function by LCMT-1.
Vitali Stanevich, Li Jiang, Kenneth A Satyshur, Yongfeng Li, Philip D Jeffrey, Martin F Semmelhack

Mol Cell· February 2011

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Probing bacterial transmembrane histidine kinase receptor-ligand interactions with natural and synthetic molecules.
Wai-Leung Ng, Yunzhou Wei, Lark J Perez, Jianping Cong, Tao Long, Martin F Semmelhack

Proc Natl Acad Sci U S A· March 2010

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The Vibrio cholerae quorum-sensing autoinducer CAI-1: analysis of the biosynthetic enzyme CqsA.
Robert C Kelly, Megan E Bolitho, Douglas A Higgins, Wenyun Lu, Wai-Leung Ng, Martin F Semmelhack

Nat Chem Biol· December 2009

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The major Vibrio cholerae autoinducer and its role in virulence factor production.
Douglas A Higgins, Megan E Pomianek, Christina M Kraml, Ronald K Taylor, Martin F Semmelhack

Nature· December 2007

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The quorum-sensing molecule autoinducer 2 regulates motility and flagellar morphogenesis in Helicobacter pylori.
Bethany A Rader, Shawn R Campagna, Martin F Semmelhack, Bonnie L Bassler, Karen Guillemin

J Bacteriol· September 2007

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Phosphorylation and processing of the quorum-sensing molecule autoinducer-2 in enteric bacteria.
Karina B Xavier, Stephen T Miller, Wenyun Lu, Jeong Hwan Kim, Joshua Rabinowitz, Martin F Semmelhack

ACS Chem Biol· February 2007

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Autoinducer 2: a concentration-dependent signal for mutualistic bacterial biofilm growth.
Alexander H Rickard, Robert J Palmer, David S Blehert, Shawn R Campagna, Martin F Semmelhack

Mol Microbiol· June 2006

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An expeditious synthesis of DPD and boron binding studies.
Martin F Semmelhack, Shawn R Campagna, Michael J Federle, Bonnie L Bassler

Org Lett· February 2005

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