Publications by authors named "Martin Hils"

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Transcriptomic analysis of intestine following administration of a transglutaminase 2 inhibitor to prevent gluten-induced intestinal damage in celiac disease.
Valeriia Dotsenko, Bernhard Tewes, Martin Hils, Ralf Pasternack, Jorma Isola

Nat Immunol· July 2024

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The Oral Transglutaminase 2 Inhibitor ZED1227 Accumulates in the Villous Enterocytes in Celiac Disease Patients during Gluten Challenge and Drug Treatment.
Jorma Isola, Markku Mäki, Martin Hils, Ralf Pasternack, Keijo Viiri

Int J Mol Sci· June 2023

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Features of ZED1227: The First-In-Class Tissue Transglutaminase Inhibitor Undergoing Clinical Evaluation for the Treatment of Celiac Disease.
Christian Büchold, Martin Hils, Uwe Gerlach, Johannes Weber, Christiane Pelzer

Cells· May 2022

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Editorial for the special issue on transglutaminases in translation - Novel tools and methods impacting on diagnostics and therapeutics.
Ralf Pasternack, Martin Hils

Anal Biochem· October 2020

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Nucleotide binding kinetics and conformational change analysis of tissue transglutaminase with switchSENSE.
Regina Staffler, Ralf Pasternack, Martin Hils, Wolfgang Kaiser, Friederike M Möller

Anal Biochem· September 2020

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Structure-Based Design of FXIIIa-Blockers: Addressing a Transient Hydrophobic Pocket in the Active Site of FXIIIa.
Martin Stieler, Christian Büchold, Marisa Schmitt, Andreas Heine, Martin Hils

ChemMedChem· May 2020

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Novel inhibitor ZED3197 as potential drug candidate in anticoagulation targeting coagulation FXIIIa (F13a).
Ralf Pasternack, Christian Büchold, Robert Jähnig, Christiane Pelzer, Michael Sommer, Martin Hils

J Thromb Haemost· January 2020

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Response to Comment by Calderón de la Barca and Sigala-Robles on Microbial Transglutaminase Used in Bread Preparation at Standard Bakery Concentrations Does Not Increase Immunodetectable Amounts of Deamidated Gliadin.
Andreas Heil, Keiichi Yokoyama, Yoshiyuki Kumazawa, Martin Hils

J Agric Food Chem· January 2018

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Microbial Transglutaminase Used in Bread Preparation at Standard Bakery Concentrations Does Not Increase Immunodetectable Amounts of Deamidated Gliadin.
Andreas Heil, Jürgen Ohsam, Bernard van Genugten, Oscar Diez, Keiichi Yokoyama, Martin Hils

J Agric Food Chem· August 2017

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Microbial transglutaminase treatment in pasta-production does not affect the immunoreactivity of gliadin with celiac disease patients' sera.
Tobias Ruh, Jürgen Ohsam, Ralf Pasternack, Keiichi Yokoyama, Yoshiyuki Kumazawa, Martin Hils

J Agric Food Chem· July 2014

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Structure of active coagulation factor XIII triggered by calcium binding: basis for the design of next-generation anticoagulants.
Martin Stieler, Johannes Weber, Martin Hils, Peter Kolb, Andreas Heine

Angew Chem Int Ed Engl· November 2013

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Differences in the inhibition of coagulation factor XIII-A from animal species revealed by Michael Acceptor- and thioimidazol based blockers.
Andreas Heil, Johannes Weber, Christian Büchold, Ralf Pasternack, Martin Hils

Thromb Res· May 2013

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Transglutaminase 6: a protein associated with central nervous system development and motor function.
Helen Thomas, Konrad Beck, Magdalena Adamczyk, Pascale Aeschlimann, Martin Langley, Martin Hils

Amino Acids· January 2013

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Immunological effects of transglutaminase-treated gluten in coeliac disease.
Luca Elli, Leda Roncoroni, Martin Hils, Ralf Pasternack, Donatella Barisani

Hum Immunol· October 2012

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Inhibition of transglutaminase 2 mitigates transcriptional dysregulation in models of Huntington disease.
Stephen J McConoughey, Manuela Basso, Zoya V Niatsetskaya, Sama F Sleiman, Natalia A Smirnova, Martin Hils

EMBO Mol Med· September 2010

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A nonradioactive dot blot assay for transglutaminase activity.
Stephen J McConoughey, Zoya V Niatsetskaya, Ralf Pasternack, Martin Hils, Rajiv R Ratan

Anal Biochem· July 2009

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Inhibition of bacterial transglutaminase by its heat-treated pro-enzyme.
Christa Pfleiderer, Martina Mainusch, Johannes Weber, Martin Hils, Hans-Lothar Fuchsbauer

Microbiol Res· August 2005

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