Publications by authors named "Martin Leeb"

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PHLPP2 is a pseudophosphatase that lost activity in the metazoan ancestor.
Tarik Husremović, Vanessa Meier, Lucas Piëch, Katharina M Siess, Sumire Antonioli, Martin Leeb

Proc Natl Acad Sci U S A· April 2025

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FoxO transcription factors actuate the formative pluripotency specific gene expression programme.
Laura Santini, Saskia Kowald, Luis Miguel Cerron-Alvan, Michelle Huth, Anna Philina Fabing, Martin Leeb

Nat Commun· September 2024

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Enhancer-promoter interactions are reconfigured through the formation of long-range multiway hubs as mouse ES cells exit pluripotency.
David Lando, Xiaoyan Ma, Yang Cao, Aleksandra Jartseva, Tim J Stevens, Martin Leeb

Mol Cell· April 2024

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Enhancers of the PAIR4 regulatory module promote distal V gene recombination at the Igh locus.
Louisa Hill, Markus Jaritz, Hiromi Tagoh, Karina Schindler, Daniela Kostanova-Poliakova, Martin Leeb

EMBO J· August 2023

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Genome-wide screening in pluripotent cells identifies Mtf1 as a suppressor of mutant huntingtin toxicity.
Giorgia Maria Ferlazzo, Anna Maria Gambetta, Sonia Amato, Noemi Cannizzaro, Silvia Angiolillo, Martin Leeb

Nat Commun· July 2023

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NMD is required for timely cell fate transitions by fine-tuning gene expression and regulating translation.
Michelle Huth, Laura Santini, Elena Galimberti, Julia Ramesmayer, Fabian Titz-Teixeira, Martin Leeb

Genes Dev· March 2022

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PHF3 regulates neuronal gene expression through the Pol II CTD reader domain SPOC.
Lisa-Marie Appel, Vedran Franke, Melania Bruno, Irina Grishkovskaya, Aiste Kasiliauskaite, Martin Leeb

Nat Commun· October 2021

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Genomic imprinting in mouse blastocysts is predominantly associated with H3K27me3.
Laura Santini, Florian Halbritter, Fabian Titz-Teixeira, Toru Suzuki, Maki Asami, Martin Leeb

Nat Commun· June 2021

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Cooperative genetic networks drive embryonic stem cell transition from naïve to formative pluripotency.
Andreas Lackner, Robert Sehlke, Marius Garmhausen, Giuliano Giuseppe Stirparo, Michelle Huth, Martin Leeb

EMBO J· April 2021

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Temporal dissection of an enhancer cluster reveals distinct temporal and functional contributions of individual elements.
Henry F Thomas, Elena Kotova, Swathi Jayaram, Axel Pilz, Merrit Romeike, Martin Leeb

Mol Cell· March 2021

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Combining fluorescence imaging with Hi-C to study 3D genome architecture of the same single cell.
David Lando, Srinjan Basu, Tim J Stevens, Andy Riddell, Kai J Wohlfahrt, Martin Leeb

Nat Protoc· May 2018

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3D structures of individual mammalian genomes studied by single-cell Hi-C.
Tim J Stevens, David Lando, Srinjan Basu, Liam P Atkinson, Yang Cao, Martin Leeb

Nature· April 2017

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Histone H3 Lysine 36 Trimethylation Is Established over the Xist Promoter by Antisense Tsix Transcription and Contributes to Repressing Xist Expression.
Tatsuya Ohhata, Mika Matsumoto, Martin Leeb, Shinwa Shibata, Satoshi Sakai

Mol Cell Biol· November 2015

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Establishment and Use of Mouse Haploid ES Cells.
Martin Leeb, Anthony C F Perry, Anton Wutz

Curr Protoc Mouse Biol· June 2015

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Genetic exploration of the exit from self-renewal using haploid embryonic stem cells.
Martin Leeb, Sabine Dietmann, Maike Paramor, Hitoshi Niwa, Austin Smith

Cell Stem Cell· March 2014

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Haploid genomes illustrate epigenetic constraints and gene dosage effects in mammals.
Martin Leeb, Anton Wutz

Epigenetics Chromatin· December 2013

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The histone deacetylase inhibitor sodium valproate causes limited transcriptional change in mouse embryonic stem cells but selectively overrides Polycomb-mediated Hoxb silencing.
Elsa Boudadi, Hannah Stower, John A Halsall, Charlotte E Rutledge, Martin Leeb

Epigenetics Chromatin· May 2013

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Germline potential of parthenogenetic haploid mouse embryonic stem cells.
Martin Leeb, Rachael Walker, Bill Mansfield, Jenny Nichols, Austin Smith

Development· September 2012

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Establishment of epigenetic patterns in development.
Martin Leeb, Anton Wutz

Chromosoma· June 2012

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Derivation of haploid embryonic stem cells from mouse embryos.
Martin Leeb, Anton Wutz

Nature· September 2011

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Polycomb complexes - Genes make sense of host defense.
Martin Leeb, Anton Wutz

Cell Cycle· July 2010

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Ring1B compacts chromatin structure and represses gene expression independent of histone ubiquitination.
Ragnhild Eskeland, Martin Leeb, Graeme R Grimes, Clémence Kress, Shelagh Boyle

Mol Cell· May 2010

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The Trithorax group protein Ash2l and Saf-A are recruited to the inactive X chromosome at the onset of stable X inactivation.
Dieter Pullirsch, Renate Härtel, Hiroyuki Kishimoto, Martin Leeb, Günter Steiner

Development· March 2010

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Polycomb complexes act redundantly to repress genomic repeats and genes.
Martin Leeb, Diego Pasini, Maria Novatchkova, Markus Jaritz, Kristian Helin

Genes Dev· February 2010

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SATB1 defines the developmental context for gene silencing by Xist in lymphoma and embryonic cells.
Ruben Agrelo, Abdallah Souabni, Maria Novatchkova, Christian Haslinger, Martin Leeb

Dev Cell· April 2009

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