Publications by authors named "Martin Leonard"

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Pulmonary Toxicity of Long, Thick MWCNT and Very Long, Thin Carboxylated MWCNT Aerosols Following 28 Days Whole-Body Exposure.
Chang Guo, Matthew D Wright, Alison Buckley, Adam Laycock, Trine Berthing, Martin O Leonard

Toxics· May 2025

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Knock-out mouse models and single particle ICP-MS reveal that SP-D and SP-A deficiency reduces agglomeration of inhaled gold nanoparticles in vivo without significant changes to overall lung clearance.
Adam Laycock, Artur Kirjakulov, Matthew Darren Wright, Konstantinos Nikolaos Bourdakos, Sumeet Mahajan, Martin O Leonard

Nanotoxicology· February 2025

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Aerosol exposure at air-liquid-interface (AE-ALI) in vitro toxicity system characterisation: Particle deposition and the importance of air control responses.
Alison Buckley, Chang Guo, Adam Laycock, Xianjin Cui, Marie-France Belinga-Desaunay-Nault, Martin Leonard

Toxicol In Vitro· October 2024

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Evaluation of the impact of iPSC differentiation protocols on transcriptomic signatures.
Vidya Chandrasekaran, Sara Wellens, Aurore Bourguignon, Ivo Djidrovski, Leonie Fransen, Martin O Leonard

Toxicol In Vitro· June 2024

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Mononuclear phagocyte sub-types in vitro display diverse transcriptional responses to dust mite exposure.
Leonie F H Fransen, Martin O Leonard

Sci Rep· June 2024

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Biodiesel exhaust particle airway toxicity and the role of polycyclic aromatic hydrocarbons.
Christopher Ogbunuzor, Leonie Francina Hendrina Fransen, Midhat Talibi, Zuhaib Khan, Abigail Dalzell, Martin Oliver Leonard

Ecotoxicol Environ Saf· July 2023

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Induced pluripotent and CD34+ stem cell derived myeloid cells display differential responses to particle and dust mite exposure.
Leonie F H Fransen, Martin O Leonard

Sci Rep· June 2023

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Direct transcriptomic comparison of xenobiotic metabolism and toxicity pathway induction of airway epithelium models at an air-liquid interface generated from induced pluripotent stem cells and primary bronchial epithelial cells.
Ivo Djidrovski, Maria Georgiou, Elena Tasinato, Martin O Leonard, Jelle Van den Bor

Cell Biol Toxicol· February 2023

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Biokinetics and Internal Dosimetry of Tritiated Steel Particles.
Rachel Smith, Michele Ellender, Chang Guo, Derek Hammond, Adam Laycock, Martin O Leonard

Toxics· October 2022

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The relationship between epigenetic age and the hallmarks of aging in human cells.
Sylwia Kabacik, Donna Lowe, Leonie Fransen, Martin Leonard, Siew-Lan Ang

Nat Aging· June 2022

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Small Airway Susceptibility to Chemical and Particle Injury.
Leonie Francina Hendrina Fransen, Martin Oliver Leonard

Respiration· April 2022

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CD34+ derived macrophage and dendritic cells display differential responses to paraquat.
Leonie F H Fransen, Martin O Leonard

Toxicol In Vitro· September 2021

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Diesel exhaust particle and dust mite induced airway inflammation is modified by cerium dioxide nanoparticles.
Kirsty Meldrum, Sarah Robertson, Isabella Römer, Tim Marczylo, Timothy W Gant, Martin O Leonard

Environ Toxicol Pharmacol· January 2020

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Pulmonary toxicity of inhaled nano-sized cerium oxide aerosols in Sprague-Dawley rats.
Chang Guo, Sarah Robertson, Ralf J M Weber, Alison Buckley, James Warren, Martin O Leonard

Nanotoxicology· August 2019

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Multi-Method Characterization of the Human Circulating Microbiome.
Emma Whittle, Martin O Leonard, Rebecca Harrison, Timothy W Gant, Daniel Paul Tonge

Front Microbiol· January 2019

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The small airway epithelium as a target for the adverse pulmonary effects of silver nanoparticle inhalation.
Chang Guo, Alison Buckley, Tim Marczylo, Joanna Seiffert, Isabella Römer, Martin O Leonard

Nanotoxicology· August 2018

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Cerium dioxide nanoparticles exacerbate house dust mite induced type II airway inflammation.
Kirsty Meldrum, Sarah B Robertson, Isabella Römer, Tim Marczylo, Lareb S N Dean, Martin O Leonard

Part Fibre Toxicol· May 2018

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Diesel exhaust particulate associated chemicals attenuate expression of CXCL10 in human primary bronchial epithelial cells.
Kirsty Meldrum, Timothy W Gant, Martin O Leonard

Toxicol In Vitro· December 2017

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Mechanistic insight into the impact of nanomaterials on asthma and allergic airway disease.
Kirsty Meldrum, Chang Guo, Emma L Marczylo, Timothy W Gant, Rachel Smith, Martin O Leonard

Part Fibre Toxicol· November 2017

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Bronchial epithelial innate and adaptive immunity signals are induced by polycyclic aromatic hydrocarbons.
Kirsty Meldrum, Timothy W Gant, Sameirah Macchiarulo, Martin O Leonard

Toxicol Res (Camb)· May 2016

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Mechanism of cisplatin proximal tubule toxicity revealed by integrating transcriptomics, proteomics, metabolomics and biokinetics.
Anja Wilmes, Chris Bielow, Christina Ranninger, Patricia Bellwon, Lydia Aschauer, Martin O Leonard

Toxicol In Vitro· December 2015

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Application of RPTEC/TERT1 cells for investigation of repeat dose nephrotoxicity: A transcriptomic study.
Lydia Aschauer, Alice Limonciel, Anja Wilmes, Sven Stanzel, Annette Kopp-Schneider, Martin O Leonard

Toxicol In Vitro· December 2015

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Development of an in vitro renal epithelial disease state model for xenobiotic toxicity testing.
Daniel Crean, Patricia Bellwon, Lydia Aschauer, Alice Limonciel, Konrad Moenks, Martin O Leonard

Toxicol In Vitro· December 2015

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Transcriptomics hit the target: Monitoring of ligand-activated and stress response pathways for chemical testing.
Alice Limonciel, Konrad Moenks, Sven Stanzel, Germaine L Truisi, Céline Parmentier, Martin O Leonard

Toxicol In Vitro· December 2015

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Ligation of TLR7 on CD19(+) CD1d(hi) B cells suppresses allergic lung inflammation via regulatory T cells.
Adnan R Khan, Sylvie Amu, Sean P Saunders, Emily Hams, Gordon Blackshields, Martin O Leonard

Eur J Immunol· June 2015

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