Publications by authors named "Martin Lock"

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Significant Differences in Capsid Properties and Potency Between Adeno-Associated Virus Vectors Produced in Sf9 and HEK293 Cells.
April Giles, Martin Lock, Shu-Jen Chen, Kevin Turner, Gregg Wesolowski

Hum Gene Ther· October 2023

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Sensitive Determination of Infectious Titer of Recombinant Adeno-Associated Viruses (rAAVs) Using TCID End-Point Dilution and Quantitative Polymerase Chain Reaction (qPCR).
Martin Lock, James Wilson, Miguel Sena-Esteves, Guangping Gao

Cold Spring Harb Protoc· May 2020

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Detection Assay for Replication-Competent Adenovirus by Concentration Passage and Real-Time Quantitative Polymerase Chain Reaction (qPCR).
Martin Lock, Mauricio Alvira, James Wilson, Miguel Sena-Esteves, Guangping Gao

Cold Spring Harb Protoc· December 2019

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Measuring the Infectious Titer of Recombinant Adenovirus Using Tissue Culture Infection Dose 50% (TCID) End-Point Dilution and Quantitative Polymerase Chain Reaction (qPCR).
Martin Lock, Michael Korn, James Wilson, Miguel Sena-Esteves, Guangping Gao

Cold Spring Harb Protoc· August 2019

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Preparation of a DNA Standard for Quantitative Polymerase Chain Reaction (qPCR).
Martin Lock, Michael Korn, James Wilson, Miguel Sena-Esteves, Guangping Gao

Cold Spring Harb Protoc· August 2019

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Stability of the adeno-associated virus 8 reference standard material.
Magalie Penaud-Budloo, Frédéric Broucque, Katell Harrouet, Mohammed Bouzelha, Sylvie Saleun, Martin Lock

Gene Ther· May 2019

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Deamidation of Amino Acids on the Surface of Adeno-Associated Virus Capsids Leads to Charge Heterogeneity and Altered Vector Function.
April R Giles, Joshua J Sims, Kevin B Turner, Lakshmanan Govindasamy, Mauricio R Alvira, Martin Lock

Mol Ther· December 2018

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Identification of an adeno-associated virus binding epitope for AVB sepharose affinity resin.
Qiang Wang, Martin Lock, Andrew J Prongay, Mauricio R Alvira, Boris Petkov

Mol Ther Methods Clin Dev· November 2015

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Manufacturing and characterization of a recombinant adeno-associated virus type 8 reference standard material.
Eduard Ayuso, Véronique Blouin, Martin Lock, Susan McGorray, Xavier Leon

Hum Gene Ther· November 2014

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Absolute determination of single-stranded and self-complementary adeno-associated viral vector genome titers by droplet digital PCR.
Martin Lock, Mauricio R Alvira, Shu-Jen Chen, James M Wilson

Hum Gene Ther Methods· April 2014

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Adeno-associated viruses as liver-directed gene delivery vehicles: focus on lipoprotein metabolism.
William R Lagor, Julie C Johnston, Martin Lock, Luk H Vandenberghe, Daniel J Rader

Methods Mol Biol· March 2014

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Biodistribution of AAV8 vectors expressing human low-density lipoprotein receptor in a mouse model of homozygous familial hypercholesterolemia.
Shu-Jen Chen, Julio Sanmiguel, Martin Lock, Deirdre McMenamin, Christine Draper

Hum Gene Ther Clin Dev· December 2013

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Analysis of particle content of recombinant adeno-associated virus serotype 8 vectors by ion-exchange chromatography.
Martin Lock, Mauricio R Alvira, James M Wilson

Hum Gene Ther Methods· February 2012

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Characterization of a recombinant adeno-associated virus type 2 Reference Standard Material.
Martin Lock, Susan McGorray, Alberto Auricchio, Eduard Ayuso, E Jeffrey Beecham

Hum Gene Ther· October 2010

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Rapid, simple, and versatile manufacturing of recombinant adeno-associated viral vectors at scale.
Martin Lock, Mauricio Alvira, Luk H Vandenberghe, Arabinda Samanta, Jaan Toelen

Hum Gene Ther· October 2010

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Efficient serotype-dependent release of functional vector into the culture medium during adeno-associated virus manufacturing.
Luk H Vandenberghe, Ru Xiao, Martin Lock, Jianping Lin, Michael Korn

Hum Gene Ther· October 2010

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Treatment of antisocial personality disorder.
Martin P Lock

Br J Psychiatry· November 2008

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Corrigendum to "Biology of AAV Serotype Vectors in Liver-Directed Gene Transfer to Nonhuman Primates".
Guangping Gao, You Lu, Roberto Calcedo, Rebecca L Grant, Peter Bell, Martin Lock

Mol Ther· July 2006

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Biology of AAV serotype vectors in liver-directed gene transfer to nonhuman primates.
Guangping Gao, You Lu, Roberto Calcedo, Rebecca L Grant, Peter Bell, Martin Lock

Mol Ther· January 2006

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Characterization of a family of chimpanzee adenoviruses and development of molecular clones for gene transfer vectors.
Soumitra Roy, Guangping Gao, You Lu, Xiangyang Zhou, Martin Lock

Hum Gene Ther· May 2004

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Production of recombinant adeno-associated type 5 (rAAV5) vectors using recombinant herpes simplex viruses containing rep and cap.
Jason T Wustner, Susan Arnold, Martin Lock, James C Richardson, Vaughn B Himes

Mol Ther· October 2002

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The 2-kilobase intron of the herpes simplex virus type 1 latency-associated transcript has a half-life of approximately 24 hours in SY5Y and COS-1 cells.
Darby L Thomas, Martin Lock, Janice M Zabolotny, Bangalore R Mohan, Nigel W Fraser

J Virol· January 2002

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Regions of the herpes simplex virus type 1 latency-associated transcript that protect cells from apoptosis in vitro and protect neuronal cells in vivo.
Maryam Ahmed, Martin Lock, Cathie G Miller, Nigel W Fraser

J Virol· January 2002

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