Publications by authors named "Martin Scheffner"

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Proteomic Profiling of Potential E6AP Substrates via Ubiquitin-based Photo-Crosslinking Assisted Affinity Enrichment.
Julian Schuck, Christine Bernecker, Martin Scheffner, Andreas Marx

Chembiochem· February 2025

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E6AP is essential for the proliferation of HPV-positive cancer cells by preventing senescence.
Alicia Avenhaus, Milica Velimirović, Julia Bulkescher, Martin Scheffner, Felix Hoppe-Seyler

PLoS Pathog· February 2025

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Biochemical and Structural Consequences of NEDD8 Acetylation.
Simon Maria Kienle, Tobias Schneider, Christine Bernecker, Janina Bracker, Andreas Marx, Martin Scheffner

Chembiochem· November 2024

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Cobalamins Function as Allosteric Activators of an Angelman Syndrome-Associated UBE3A/E6AP Variant.
Franziska Müller, Jasmin Jansen, Fabian Offensperger, Daniela Eichbichler, Florian Stengel, Martin Scheffner

Chembiochem· May 2024

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Phase separation promotes the activity of HECT E3 ligases-A word of caution.
Daniela Eichbichler, Christine Bernecker, Florian Stengel, Martin Scheffner

Proc Natl Acad Sci U S A· April 2024

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Interactome of intact chromatosome variants with site-specifically ubiquitylated and acetylated linker histone H1.2.
Philip Saumer, Martin Scheffner, Andreas Marx, Florian Stengel

Nucleic Acids Res· January 2024

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Thermostable protein-stabilized gold nanoclusters as a peroxidase mimic.
Özlem Akyüz, Maite Mißun, Rose Rosenberg, Martin Scheffner, Andreas Marx

Nanoscale Adv· November 2023

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FAT10 and NUB1L cooperate to activate the 26S proteasome.
Florian Brockmann, Nicola Catone, Christine Wünsch, Fabian Offensperger, Martin Scheffner

Life Sci Alliance· August 2023

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Chemoproteomic discovery of a human RNA ligase.
Yizhi Yuan, Florian M Stumpf, Lisa A Schlor, Olivia P Schmidt, Philip Saumer, Martin Scheffner

Nat Commun· February 2023

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Electrostatic and steric effects underlie acetylation-induced changes in ubiquitin structure and function.
Simon Maria Kienle, Tobias Schneider, Katrin Stuber, Christoph Globisch, Jasmin Jansen, Martin Scheffner

Nat Commun· September 2022

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MDM2 binds and ubiquitinates PARP1 to enhance DNA replication fork progression.
Celeste Giansanti, Valentina Manzini, Antje Dickmanns, Achim Dickmanns, Maria Dilia Palumbieri, Martin Scheffner

Cell Rep· May 2022

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Generation and Characterization of Site-Specifically Mono-Ubiquitylated p53.
Alexandra Julier, Vanessa Radtke, Andreas Marx, Martin Scheffner

Chembiochem· March 2022

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Titin kinase ubiquitination aligns autophagy receptors with mechanical signals in the sarcomere.
Julius Bogomolovas, Jennifer R Fleming, Barbara Franke, Bruno Manso, Bernd Simon, Martin Scheffner

EMBO Rep· October 2021

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Chemical proteomic profiling reveals protein interactors of the alarmones diadenosine triphosphate and tetraphosphate.
Lena Krüger, Christoph J Albrecht, Hannah K Schammann, Florian M Stumpf, Marie L Niedermeier, Martin Scheffner

Nat Commun· October 2021

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Structural and functional consequences of NEDD8 phosphorylation.
Katrin Stuber, Tobias Schneider, Jill Werner, Michael Kovermann, Andreas Marx, Martin Scheffner

Nat Commun· October 2021

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Interactome of Site-Specifically Acetylated Linker Histone H1.
Eva Höllmüller, Katharina Greiner, Simon M Kienle, Martin Scheffner, Andreas Marx

J Proteome Res· September 2021

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Site-specific ubiquitylation acts as a regulator of linker histone H1.
Eva Höllmüller, Simon Geigges, Marie L Niedermeier, Kai-Michael Kammer, Simon M Kienle, Martin Scheffner

Nat Commun· June 2021

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Identification of Small-Molecule Activators of the Ubiquitin Ligase E6AP/UBE3A and Angelman Syndrome-Derived E6AP/UBE3A Variants.
Fabian Offensperger, Franziska Müller, Jasmin Jansen, Daniel Hammler, Kathrin H Götz, Martin Scheffner

Cell Chem Biol· December 2020

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Correction to Machine Learning Driven Analysis of Large Scale Simulations Reveals Conformational Characteristics of Ubiquitin Chains.
Andrej Berg, Leon Franke, Martin Scheffner, Christine Peter

J Chem Theory Comput· November 2020

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A ubiquitin variant-based affinity approach selectively identifies substrates of the ubiquitin ligase E6AP in complex with HPV-11 E6 or HPV-16 E6.
Felix A Ebner, Carolin Sailer, Daniela Eichbichler, Jasmin Jansen, Anna Sladewska-Marquardt, Martin Scheffner

J Biol Chem· October 2020

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The Length of a Ubiquitin Chain: A General Factor for Selective Recognition by Ubiquitin-Binding Proteins.
Joachim Lutz, Eva Höllmüller, Martin Scheffner, Andreas Marx, Florian Stengel

Angew Chem Int Ed Engl· July 2020

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Fluorescently Labelled ATP Analogues for Direct Monitoring of Ubiquitin Activation.
Daniel Hammler, Katrin Stuber, Fabian Offensperger, Martin Scheffner, Andreas Zumbusch

Chemistry· May 2020

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Machine Learning Driven Analysis of Large Scale Simulations Reveals Conformational Characteristics of Ubiquitin Chains.
Andrej Berg, Leon Franke, Martin Scheffner, Christine Peter

J Chem Theory Comput· May 2020

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Effects of the antifungal agent ciclopirox in HPV-positive cancer cells: Repression of viral E6/E7 oncogene expression and induction of senescence and apoptosis.
Julia A Braun, Anja L Herrmann, Johanna I Blase, Kristin Frensemeier, Julia Bulkescher, Martin Scheffner

Int J Cancer· January 2020

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Assembly of branched ubiquitin oligomers by click chemistry.
Xiaohui Zhao, Martin Scheffner, Andreas Marx

Chem Commun (Camb)· October 2019

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