Publications by authors named "Martin Sterba"

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Prenatal paroxetine dysregulates monoamine homeostasis and affects placental hemodynamics in the rat fetoplacental unit.
Hana Horackova, Ivana Musilova-Kacerovska, Cilia Abad, Rona Karahoda, Veronika Vachalova, Martin Sterba

Biomed Pharmacother· November 2025

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Daunorubicin and its hydroxy metabolite in cardiomyocytes: insights into cellular kinetics, toxicity, DNA damage, and dexrazoxane-induced cardioprotection.
Lenka Applová, Paulína Dudášová-Hatoková, Jan Kubeš, Nela Váňová, Veronika Keresteš

Arch Toxicol· September 2025

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Impact of intraamniotic inflammation on tryptophan metabolism in the placenta-fetal brain axis in rats.
Cilia Abad, Ivana Musilova, Eva Cifkova, Ramon Portillo, Fiona Kumnova, Martin Sterba

Reproduction· May 2025

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Topobexin targets the Topoisomerase II ATPase domain for beta isoform-selective inhibition and anthracycline cardioprotection.
Jan Kubeš, Galina Karabanovich, Anh T Q Cong, Iuliia Melnikova, Olga Lenčová

Nat Commun· May 2025

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Methodological Aspects of μLC-MS/MS for Wide-Scale Proteomic Analysis of Anthracycline-Induced Cardiomyopathy.
Rudolf Kupčík, Olga Lenčová, Yvona Mazurová, Martin Štěrba, Marie Vajrychová

ACS Omega· April 2025

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Volumetric absorptive microsampling meets electromembrane extraction for the first time: Case example of doxorubicin and its metabolite in whole blood samples.
Adam Reguli, Hana Bavlovič Piskáčková, Olga Lenčová-Popelová, Petra Kollárová-Brázdová, Martin Štěrba

Anal Chim Acta· January 2025

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Characterization of a new model of chemotherapy-induced heart failure with reduced ejection fraction and nephrotic syndrome in Ren-2 transgenic rats.
Olga Gawrys, Šárka Jíchová, Matúš Miklovič, Zuzana Husková, Soňa Kikerlová

Hypertens Res· November 2024

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Exploring the effects of topoisomerase II inhibitor XK469 on anthracycline cardiotoxicity and DNA damage.
Veronika Keresteš, Jan Kubeš, Lenka Applová, Petra Kollárová, Olga Lenčová-Popelová

Toxicol Sci· March 2024

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Cardiac miRNA expression during the development of chronic anthracycline-induced cardiomyopathy using an experimental rabbit model.
Michaela Adamcova, Helena Parova, Olga Lencova-Popelova, Petra Kollarova-Brazdova, Ivana Baranova, Martin Sterba

Front Pharmacol· January 2024

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Targeted treatment of severe vascular malformations harboring PIK3CA and TEK mutations with alpelisib is highly effective with limited toxicity.
Martin Sterba, Petra Pokorna, Renata Faberova, Blanka Pinkova, Jarmila Skotakova, Jaroslav Sterba

Sci Rep· June 2023

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Development of a Rat Model of Intra-Amniotic Inflammation Ultrasound-Guided Administration of a Triggering Agent in the Gestational Sac to Enable Analysis of Individual Amniotic Fluid Samples.
Jaroslav Stranik, Marian Kacerovsky, Martin Sterba, Ctirad Andrys, Cilia Abad

Front Pharmacol· April 2022

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Primary prevention of chronic anthracycline cardiotoxicity with ACE inhibitor is temporarily effective in rabbits, but benefits wane in post-treatment follow-up.
Zuzana Pokorná, Petra Kollárová-Brázdová, Olga Lenčová-Popelová, Eduard Jirkovský, Jan Kubeš

Clin Sci (Lond)· January 2022

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Clinically Translatable Prevention of Anthracycline Cardiotoxicity by Dexrazoxane Is Mediated by Topoisomerase II Beta and Not Metal Chelation.
Eduard Jirkovský, Anna Jirkovská, Hana Bavlovič-Piskáčková, Veronika Skalická, Zuzana Pokorná

Circ Heart Fail· November 2021

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Prodrug of ICRF-193 provides promising protective effects against chronic anthracycline cardiotoxicity in a rabbit model in vivo.
Petra Kollárová-Brázdová, Olga Lenčová-Popelová, Galina Karabanovich, Júlia Kocúrová-Lengvarská, Jan Kubeš

Clin Sci (Lond)· August 2021

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Structure-Activity Relationship Study of Dexrazoxane Analogues Reveals ICRF-193 as the Most Potent Bisdioxopiperazine against Anthracycline Toxicity to Cardiomyocytes Due to Its Strong Topoisomerase IIβ Interactions.
Anna Jirkovská, Galina Karabanovich, Jan Kubeš, Veronika Skalická, Iuliia Melnikova

J Med Chem· April 2021

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Spindle Cell Hemangioma and Atypically Localized Juxtaglomerular Cell Tumor in a Patient with Hereditary BRIP1 Mutation: A Case Report.
Jan Papez, Jiri Starha, Pavel Zerhau, Denisa Pavlovska, Marta Jezova, Martin Sterba, Jaroslav Sterba

Genes (Basel)· February 2021

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Development of water-soluble prodrugs of the bisdioxopiperazine topoisomerase IIβ inhibitor ICRF-193 as potential cardioprotective agents against anthracycline cardiotoxicity.
Hana Bavlovič Piskáčková, Hana Jansová, Jan Kubeš, Galina Karabanovich, Nela Váňová

Sci Rep· February 2021

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Role of serum biomarkers in cancer patients receiving cardiotoxic cancer therapies: a position statement from the Cardio-Oncology Study Group of the Heart Failure Association and the Cardio-Oncology Council of the European Society of Cardiology.
Radek Pudil, Christian Mueller, Jelena Čelutkienė, Peter A Henriksen, Dan Lenihan

Eur J Heart Fail· November 2020

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Effect of Hydrocortisone on Mortality and Organ Support in Patients With Severe COVID-19: The REMAP-CAP COVID-19 Corticosteroid Domain Randomized Clinical Trial.
Derek C Angus, Lennie Derde, Farah Al-Beidh, Djillali Annane, Yaseen Arabi, Martin Sterba

JAMA· October 2020

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Anticancer pentamethinium salt is a potent photosensitizer inducing mitochondrial disintegration and apoptosis upon red light illumination.
Radovan Krejcir, Tomas Briza, Martin Sterba, Oliver Simoncik, Petr Muller

J Photochem Photobiol B· August 2020

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Investigation of Structure-Activity Relationships of Dexrazoxane Analogs Reveals Topoisomerase II Interaction as a Prerequisite for Effective Protection against Anthracycline Cardiotoxicity.
Petra Kollárová-Brázdová, Anna Jirkovská, Galina Karabanovich, Zuzana Pokorná, Hana Bavlovič Piskáčková

J Pharmacol Exp Ther· June 2020

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and investigation of cardiotoxicity associated with anticancer proteasome inhibitors and their combination with anthracycline.
Zuzana Pokorna, Eduard Jirkovsky, Marketa Hlavackova, Hana Jansova, Anna Jirkovska, Martin Sterba

Clin Sci (Lond)· August 2019

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A Cyclic Pentamethinium Salt Induces Cancer Cell Cytotoxicity through Mitochondrial Disintegration and Metabolic Collapse.
Radovan Krejcir, Lucie Krcova, Pavlina Zatloukalova, Tomas Briza, Philip J Coates, Martin Sterba

Int J Mol Sci· August 2019

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Comprehensive review of cardiovascular toxicity of drugs and related agents.
Přemysl Mladěnka, Lenka Applová, Jiří Patočka, Vera Marisa Costa, Fernando Remiao

Med Res Rev· July 2018

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Pharmacokinetics of the Cardioprotective Drug Dexrazoxane and Its Active Metabolite ADR-925 with Focus on Cardiomyocytes and the Heart.
Eduard Jirkovský, Anna Jirkovská, Jan Bureš, Jaroslav Chládek, Olga Lenčová

J Pharmacol Exp Ther· March 2018

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