Publications by authors named "Martin Werle"

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Ileum targeted semaglutide delivery and pharmacokinetic study in an experimental porcine animal model via oesophagogastroduodenoscopic administration.
Michael Blümlinger, Flora Hamar, Martin Werle, Florian Föger, Martina Hrouda

J Control Release· November 2025

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Peroral peptide delivery: Peptidase inhibition as a key concept for commercial drug products.
Martin Werle, Florian Föger

Bioorg Med Chem· June 2018

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A mucoadhesive nanoparticulate system for the simultaneous delivery of macromolecules and permeation enhancers to the intestinal mucosa.
Abdallah Makhlof, Martin Werle, Yuichi Tozuka, Hirofumi Takeuchi

J Control Release· January 2011

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Nanoparticles of glycol chitosan and its thiolated derivative significantly improved the pulmonary delivery of calcitonin.
Abdallah Makhlof, Martin Werle, Yuichi Tozuka, Hirofumi Takeuchi

Int J Pharm· September 2010

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Carbopol-lectin conjugate coated liposomes for oral peptide delivery.
Martin Werle, Abdallah Makhlof, Hirofumi Takeuchi

Chem Pharm Bull (Tokyo)· March 2010

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Oral protein delivery: a patent review of academic and industrial approaches.
Martin Werle, Abdallah Makhlof, Hirofumi Takeuchi

Recent Pat Drug Deliv Formul· June 2009

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Modified chitosans for oral drug delivery.
Martin Werle, Hirofumi Takeuchi, Andreas Bernkop-Schnürch

J Pharm Sci· May 2009

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Chitosan-aprotinin coated liposomes for oral peptide delivery: Development, characterisation and in vivo evaluation.
Martin Werle, Hirofumi Takeuchi

Int J Pharm· March 2009

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Development and in vitro characterization of liposomes coated with thiolated poly(acrylic acid) for oral drug delivery.
Martin Werle, Kohei Hironaka, Hirofumi Takeuchi, Herbert Hoyer

Drug Dev Ind Pharm· February 2009

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New-generation efflux pump inhibitors.
Martin Werle, Hirofumi Takeuchi, Andreas Bernkop-Schnürch

Expert Rev Clin Pharmacol· May 2008

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Natural and synthetic polymers as inhibitors of drug efflux pumps.
Martin Werle

Pharm Res· March 2008

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Thiolated chitosans: useful excipients for oral drug delivery.
Martin Werle, Andreas Bernkop-Schnürch

J Pharm Pharmacol· March 2008

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Effect of a thiolated polymer on oral paclitaxel absorption and tumor growth in rats.
Florian Föger, Suchinda Malaivijitnond, Thanakul Wannaprasert, Christian Huck, Andreas Bernkop-Schnürch, Martin Werle

J Drug Target· February 2008

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Polymeric and low molecular mass efflux pump inhibitors for oral drug delivery.
Martin Werle

J Pharm Sci· January 2008

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Synthesis and in vitro evaluation of thiolated hyaluronic acid for mucoadhesive drug delivery.
Krum Kafedjiiski, Ram K R Jetti, Florian Föger, Herbert Hoyer, Martin Werle

Int J Pharm· October 2007

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Oral peptide delivery: in-vitro evaluation of thiolated alginate/poly(acrylic acid) microparticles.
Alexander Greimel, Martin Werle, Andreas Bernkop-Schnürch

J Pharm Pharmacol· September 2007

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Design and evaluation of a chitosan-aprotinin conjugate for the peroral delivery of therapeutic peptides and proteins susceptible to enzymatic degradation.
Martin Werle, Brigitta Loretz, Daniel Entstrasser, Florian Föger

J Drug Target· June 2007

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Evaluation of in vitro enzymatic degradation of various thiomers and cross-linked thiomers.
Krum Kafedjiiski, Florian Föger, Herbert Hoyer, Andreas Bernkop-Schnürch, Martin Werle

Drug Dev Ind Pharm· February 2007

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Oral gene delivery: Strategies to improve stability of pDNA towards intestinal digestion.
Brigitta Loretz, Florian Föger, Martin Werle, Andreas Bernkop-Schnürch

J Drug Target· June 2006

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Degradation of teriparatide by gastro-intestinal proteolytic enzymes.
Martin Werle, Annette Samhaber, Andreas Bernkop-Schnürch

J Drug Target· April 2006

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The potential of cystine-knot microproteins as novel pharmacophoric scaffolds in oral peptide drug delivery.
Martin Werle, Thierry Schmitz, Hong-Lei Huang, Alexander Wentzel, Harald Kolmar

J Drug Target· April 2006

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Glutathione and thiolated chitosan inhibit multidrug resistance P-glycoprotein activity in excised small intestine.
Martin Werle, Martin Hoffer

J Control Release· March 2006

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Improved synthesis and in vitro characterization of chitosan-thioethylamidine conjugate.
Krum Kafedjiiski, Martin Hoffer, Martin Werle, Andreas Bernkop-Schnürch

Biomaterials· January 2006

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Synthesis and in vitro evaluation of a novel chitosan-glutathione conjugate.
Krum Kafedjiiski, Florian Föger, Martin Werle, Andreas Bernkop-Schnürch

Pharm Res· September 2005

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