Publications by authors named "Mary E Simcox"

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CUE-101, a Novel E7-pHLA-IL2-Fc Fusion Protein, Enhances Tumor Antigen-Specific T-Cell Activation for the Treatment of HPV16-Driven Malignancies.
Steven N Quayle, Natasha Girgis, Dharma R Thapa, Zohra Merazga, Melissa M Kemp, Mary Ellen Simcox

Clin Cancer Res· April 2020

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Exposure and Tumor Fn14 Expression as Determinants of Pharmacodynamics of the Anti-TWEAK Monoclonal Antibody RG7212 in Patients with Fn14-Positive Solid Tumors.
Didier Meulendijks, Ulrik N Lassen, Lillian L Siu, Alwin D R Huitema, Vaios Karanikas, Mary E Simcox

Clin Cancer Res· February 2016

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A phase I monotherapy study of RG7212, a first-in-class monoclonal antibody targeting TWEAK signaling in patients with advanced cancers.
Ulrik N Lassen, Didier Meulendijks, Lilian L Siu, Vaios Karanikas, Morten Mau-Sorensen, Mary E Simcox

Clin Cancer Res· January 2015

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Antitumor activity of BRAF inhibitor vemurafenib in preclinical models of BRAF-mutant colorectal cancer.
Hong Yang, Brian Higgins, Kenneth Kolinsky, Kathryn Packman, William D Bradley, Mary Ellen Simcox

Cancer Res· February 2012

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Resistance to selective BRAF inhibition can be mediated by modest upstream pathway activation.
Fei Su, William D Bradley, Qiongqing Wang, Hong Yang, Lizhong Xu, Mary Ellen Simcox

Cancer Res· February 2012

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RG7204 (PLX4032), a selective BRAFV600E inhibitor, displays potent antitumor activity in preclinical melanoma models.
Hong Yang, Brian Higgins, Kenneth Kolinsky, Kathryn Packman, Zenaida Go, Mary Ellen Simcox

Cancer Res· July 2010

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A new series of potent oxindole inhibitors of CDK2.
Kin-Chun Luk, Mary Ellen Simcox, Andy Schutt, Karen Rowan, Thelma Thompson

Bioorg Med Chem Lett· February 2004

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3,5,6-Trisubstituted naphthostyrils as CDK2 inhibitors.
Jin-Jun Liu, Apostolos Dermatakis, Christine Lukacs, Fred Konzelmann, Yi Chen, Mary Ellen Simcox

Bioorg Med Chem Lett· August 2003

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