Publications by authors named "Mary Kuffel"

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Endoxifen downregulates AKT phosphorylation through protein kinase C beta 1 inhibition in ERα+ breast cancer.
Swaathi Jayaraman, Xinyan Wu, Krishna R Kalari, Xiaojia Tang, Mary J Kuffel

NPJ Breast Cancer· December 2023

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Antitumor activity of Z-endoxifen in aromatase inhibitor-sensitive and aromatase inhibitor-resistant estrogen receptor-positive breast cancer.
Swaathi Jayaraman, Xiaonan Hou, Mary J Kuffel, Vera J Suman, Tanya L Hoskin

Breast Cancer Res· May 2020

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First-in-Human Phase I Study of the Tamoxifen Metabolite Z-Endoxifen in Women With Endocrine-Refractory Metastatic Breast Cancer.
Matthew P Goetz, Vera J Suman, Joel M Reid, Don W Northfelt, Michael A Mahr, Mary Kuffel

J Clin Oncol· October 2017

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Comparative Metabolism of Batracylin (NSC 320846) and N-acetylbatracylin (NSC 611001) Using Human, Dog, and Rat Preparations .
Joseph M Covey, Joel M Reid, Sarah A Buhrow, Mary Kuffel, Chad Walden

J Drug Metab Toxicol· June 2016

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Pharmacokinetics of endoxifen and tamoxifen in female mice: implications for comparative in vivo activity studies.
Joel M Reid, Matthew P Goetz, Sarah A Buhrow, Chad Walden, Stephanie L Safgren, Mary J Kuffel

Cancer Chemother Pharmacol· December 2014

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Loss of heterozygosity at the CYP2D6 locus in breast cancer: implications for germline pharmacogenetic studies.
Matthew P Goetz, James X Sun, Vera J Suman, Grace O Silva, Charles M Perou, Mary J Kuffel

J Natl Cancer Inst· December 2014

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UGT1A1 genotype-guided phase I study of irinotecan, oxaliplatin, and capecitabine.
Matthew P Goetz, Heidi A McKean, Joel M Reid, Sumithra J Mandrekar, Angelina D Tan, Mary A Kuffel

Invest New Drugs· December 2013

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CYP2D6 metabolism and patient outcome in the Austrian Breast and Colorectal Cancer Study Group trial (ABCSG) 8.
Matthew P Goetz, Vera J Suman, Tanya L Hoskin, Michael Gnant, Martin Filipits, Mary Kuffel

Clin Cancer Res· January 2013

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Methylenedioxy- and ethylenedioxy-fused indolocarbazoles: potent human topoisomerase I inhibitors and antitumor agents.
David E Zembower, Yongping Xie, Ali Koohang, Mary J Kuffel, Matthew M Ames

Anticancer Agents Med Chem· November 2012

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SULT1A1, CYP2C19 and disease-free survival in early breast cancer patients receiving tamoxifen.
Ann M Moyer, Vera J Suman, Richard M Weinshilboum, Rajeswari Avula, John L Black, Mary J Kuffel

Pharmacogenomics· November 2011

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Pharmacokinetics, pharmacodynamics and metabolism of the dimeric pyrrolobenzodiazepine SJG-136 in rats.
Joel M Reid, Sarah A Buhrow, Mary J Kuffel, Lee Jia, Victoria J Spanswick

Cancer Chemother Pharmacol· September 2011

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Synergistic interactions between aminoflavone, paclitaxel and camptothecin in human breast cancer cells.
Kathryn E Reinicke, Mary J Kuffel, Matthew P Goetz, Matthew M Ames

Cancer Chemother Pharmacol· August 2010

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Association between CYP2D6 polymorphisms and outcomes among women with early stage breast cancer treated with tamoxifen.
Werner Schroth, Matthew P Goetz, Ute Hamann, Peter A Fasching, Marcus Schmidt, Mary J Kuffel

JAMA· October 2009

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Phase I/II trial of pyrazoloacridine and carboplatin in patients with recurrent glioma: a North Central Cancer Treatment Group trial.
Evanthia Galanis, Jan C Buckner, Matthew J Maurer, Joel M Reid, Mary J Kuffel

Invest New Drugs· October 2005

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Rat and human liver cytochrome P-450 isoform metabolism of ecteinascidin 743 does not predict gender-dependent toxicity in humans.
Joel M Reid, Mary J Kuffel, Stacie L Ruben, Jose J Morales, Kenneth L Rinehart

Clin Cancer Res· September 2002

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Activation of the antitumor agent aminoflavone (NSC 686288) is mediated by induction of tumor cell cytochrome P450 1A1/1A2.
Mary J Kuffel, Jennifer C Schroeder, Lori J Pobst, Stephen Naylor, Joel M Reid

Mol Pharmacol· July 2002

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