Publications by authors named "Masato Fukae"

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Effect of Rifampicin on the Pharmacokinetics of Valemetostat and Its Primary Metabolite: A Phase 1 Study in Healthy Participants.
Masaya Tachibana, Shunji Matsuki, Akifumi Kurata, Masato Fukae, Sayaka Shinohara

Clin Transl Sci· July 2025

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Population pharmacokinetics of total and unbound valemetostat and platelet dynamics in healthy volunteers and patients with non-Hodgkin lymphoma.
Masato Fukae, Kyle Baron, Masaya Tachibana, John Mondick, Takako Shimizu

CPT Pharmacometrics Syst Pharmacol· October 2024

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Bayesian sparse regression for exposure-response analyses of efficacy and safety endpoints to justify the clinical dose of valemetostat for adult T-cell leukemia/lymphoma.
Masato Fukae, James Rogers, Ramon Garcia, Masaya Tachibana, Takako Shimizu

CPT Pharmacometrics Syst Pharmacol· October 2024

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Exposure-response analysis of the efficacy and safety of esaxerenone, a novel nonsteroidal mineralocorticoid receptor blocker, in hypertensive patients with or without diabetic kidney disease.
Kazutaka Yoshihara, Masato Fukae, Helen Kastrissios, Russell Wada, Takako Shimizu

Drug Metab Pharmacokinet· April 2024

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Safety, Tolerability, and Pharmacokinetics of Valemetostat Tablets and the Effect of Food on Valemetostat Pharmacokinetics in Healthy Subjects: Two Phase 1 Studies.
Masaya Tachibana, Shunji Matsuki, Kaoru Toyama, Yutaro Maekawa, Masato Fukae

Clin Pharmacol Drug Dev· January 2024

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Trastuzumab Deruxtecan Dosing in Human Epidermal Growth Factor Receptor 2-Positive Gastric Cancer: Population Pharmacokinetic Modeling and Exposure-Response Analysis.
Kazutaka Yoshihara, Yoshimasa Kobayashi, Seiko Endo, Masato Fukae, Stefanie Hennig

J Clin Pharmacol· November 2023

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Population pharmacokinetics of esaxerenone, a novel non-steroidal mineralocorticoid receptor blocker, in patients with essential hypertension, patients with diabetic nephropathy, and healthy volunteers.
Kazutaka Yoshihara, Masato Fukae, Helen Kastrissios, Russell Wada, Takako Shimizu

Drug Metab Pharmacokinet· October 2023

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Characterization of changes in HbA1c in patients with and without secondary failure after metformin treatments by a population pharmacodynamic analysis using mixture models.
Yoko Tamaki, Kunio Maema, Makoto Kakara, Masato Fukae, Ryoko Kinoshita

Drug Metab Pharmacokinet· December 2018

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Safety, Tolerability, and Pharmacokinetics of NK-104-NP.
Kaku Nakano, Tetsuya Matoba, Jun-Ichiro Koga, Yushi Kashihara, Masato Fukae

Int Heart J· September 2018

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Population pharmacodynamic analysis of hemoglobin A1c-lowering effects by adding treatment of DPP-4 inhibitors (sitagliptin) in type 2 diabetes mellitus patients based on electronic medical records.
Makoto Kakara, Hiroko Nomura, Mai Ezaki, Masato Fukae, Takeshi Hirota

J Diabetes Complications· March 2018

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Population Pharmacodynamic Analysis of Uric Acid-Lowering Effects of Febuxostat Based on Electronic Medical Records in Two Hospitals.
Shota Muraki, Kuniaki Moriki, Saki Shigematsu, Masato Fukae, Makoto Kakara

J Clin Pharmacol· March 2018

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Small-Dosing Clinical Study: Pharmacokinetic, Pharmacogenomic (SLCO2B1 and ABCG2), and Interaction (Atorvastatin and Grapefruit Juice) Profiles of 5 Probes for OATP2B1 and BCRP.
Yushi Kashihara, Ichiro Ieiri, Takashi Yoshikado, Kazuya Maeda, Masato Fukae

J Pharm Sci· September 2017

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Population pharmacokinetic-pharmacodynamic modeling and model-based prediction of docetaxel-induced neutropenia in Japanese patients with non-small cell lung cancer.
Masato Fukae, Yoshimasa Shiraishi, Takeshi Hirota, Yuka Sasaki, Mika Yamahashi

Cancer Chemother Pharmacol· November 2016

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Circulating intestine-derived exosomal miR-328 in plasma, a possible biomarker for estimating BCRP function in the human intestines.
Keisuke Gotanda, Takeshi Hirota, Jumpei Saito, Masato Fukae, Yu Egashira

Sci Rep· August 2016

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Sulfasalazine disposition in a subject with 376C>T (nonsense mutation) and 421C>A variants in the ABCG2 gene.
Keisuke Gotanda, Tomoko Tokumoto, Takeshi Hirota, Masato Fukae, Ichiro Ieiri

Br J Clin Pharmacol· November 2015

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Population pharmacodynamic analysis of LDL-cholesterol lowering effects by statins and co-medications based on electronic medical records.
Makoto Kakara, Hiroko Nomura, Masato Fukae, Keisuke Gotanda, Takeshi Hirota

Br J Clin Pharmacol· October 2014

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Korean, Japanese, and Chinese populations featured similar genes encoding drug-metabolizing enzymes and transporters: a DMET Plus microarray assessment.
SoJeong Yi, Hyungmi An, Howard Lee, Sangin Lee, Ichiro Ieiri, Masato Fukae

Pharmacogenet Genomics· October 2014

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Clinical impact of genetic variants of drug transporters in different ethnic groups within and across regions.
Chiho Ono, Hironori Kikkawa, Akiyuki Suzuki, Misaki Suzuki, Yuichi Yamamoto, Masato Fukae

Pharmacogenomics· November 2013

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Pharmacogenomic/pharmacokinetic assessment of a four-probe cocktail for CYPs and OATPs following oral microdosing.
Ichiro Ieiri, Masato Fukae, Kazuya Maeda, Yukie Ando, Miyuki Kimura

Int J Clin Pharmacol Ther· October 2012

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