Publications by authors named "Masato Ohbuchi"

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Modeling of Blood-Brain Barrier (BBB) Dysfunction and Immune Cell Migration Using Human BBB-on-a-Chip for Drug Discovery Research.
Masato Ohbuchi, Mayu Shibuta, Kazuhiro Tetsuka, Haruna Sasaki-Iwaoka, Masayo Oishi

Int J Mol Sci· June 2024

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Preclinical Characterization of ASP2713, a Novel Igβ and FcγRIIB Cross-Linking Antibody, for Prediction of Human Pharmacokinetics and Clinically Effective Dose.
Kentaro Konishi, Koji Nakamura, Yuichi Hanada, Yukihiro Kitanaga, Satoshi Kubo, Masato Ohbuchi

J Pharm Sci· September 2022

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Modelling and Prevention of Acute Kidney Injury through Ischemia and Reperfusion in a Combined Human Renal Proximal Tubule/Blood Vessel-on-a-Chip.
Marianne K Vormann, Laura M Tool, Masato Ohbuchi, Linda Gijzen, Remko van Vught

Kidney360· February 2022

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Reconstituted Human Organ Models as a Translational Tool for Human Organ Response: Definition, Expectations, Cases, and Strategies for Implementation in Drug Discovery and Development.
Kazuhiro Tetsuka, Masato Ohbuchi, Tetsuhiro Kawabe, Takayuki Goto, Fumiko Kiyonaga

Biol Pharm Bull· September 2020

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[Application of novel 3D-bioprinted human liver tissue models in drug discovery research].
Masato Ohbuchi

Nihon Yakurigaku Zasshi· August 2019

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Recent Progress in Hepatocyte Culture Models and Their Application to the Assessment of Drug Metabolism, Transport, and Toxicity in Drug Discovery: The Value of Tissue Engineering for the Successful Development of a Microphysiological System.
Kazuhiro Tetsuka, Masato Ohbuchi, Kenji Tabata

J Pharm Sci· September 2017

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Murine Cyp3a knockout chimeric mice with humanized liver: prediction of the metabolic profile of nefazodone in humans.
Naoyuki Nakada, Akio Kawamura, Hidetaka Kamimura, Koya Sato, Yasuhiro Kazuki, Masato Ohbuchi

Biopharm Drug Dispos· January 2016

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Development of Murine Cyp3a Knockout Chimeric Mice with Humanized Liver.
Kota Kato, Masato Ohbuchi, Satoko Hamamura, Hiroki Ohshita, Yasuhiro Kazuki

Drug Metab Dispos· August 2015

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Coordinated roles of pregnane X receptor and constitutive androstane receptor in autoinduction of voriconazole metabolism in mice.
Masato Ohbuchi, Kouichi Yoshinari, Hayato Kaneko, Satoru Matsumoto, Akiko Inoue

Antimicrob Agents Chemother· March 2013

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Different effects of proton pump inhibitors and famotidine on the clopidogrel metabolic activation by recombinant CYP2B6, CYP2C19 and CYP3A4.
Masato Ohbuchi, Kiyoshi Noguchi, Akio Kawamura, Takashi Usui

Xenobiotica· July 2012

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Role of enzymatic N-hydroxylation and reduction in flutamide metabolite-induced liver toxicity.
Masato Ohbuchi, Masaaki Miyata, Daichi Nagai, Miki Shimada, Kouichi Yoshinari

Drug Metab Dispos· January 2009

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