Publications by authors named "Masato Ohtsuka"

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Generation of mice expressing liver-specific fluorescent genes and the optimal conditions for signal detection via in vivo imaging.
Shuho Hori, Hideki Hayashi, Kayoko Iwao, Ayaka Nakamura, Hideaki Sumiyoshi, Masato Ohtsuka

Exp Anim· September 2025

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Molecular and genetic evidence for the role of AMBRA1 in suppressing S-phase entry and tumorigenesis.
Hisako Akatsuka, Tomohiro Kashikawa, Kaori Masuhara, Mizuki Tokusanai, Chenyang Li, Masato Ohtsuka

iScience· August 2025

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The Variant Causing Autosomal Dominant Deafness in a Nicaraguan Family Enhances Sensitivity to Noise-Induced Hearing Loss in Mice.
Evan B Hale, Barbara Vona, Richard J Goodyear, Richard T Osgood, Sami S Amr, Masato Ohtsuka

medRxiv· August 2025

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Channel synapse mediates neurotransmission of airway protective chemoreflexes.
Shogo Soma, Norihito Hayatsu, Kengo Nomura, Mark W Sherwood, Tatsuro Murakami, Masato Ohtsuka

Cell· May 2025

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In vivo functional significance of direct physical interaction between Period and Cryptochrome in mammalian circadian rhythm generation.
Junko Kawabe, Kohhei Kajihara, Yohei Matsuyama, Yukiya Mori, Teruki Hamano, Masato Ohtsuka

PNAS Nexus· December 2024

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Abcb4-defect cholangitis mouse model with hydrophobic bile acid composition by in vivo liver-specific gene deletion.
Kota Tsuruya, Keiko Yokoyama, Yusuke Mishima, Kinuyo Ida, Takuma Araki, Masato Ohtsuka

J Lipid Res· September 2024

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PTBP1 protects Y RNA from cleavage leading to its apoptosis-specific degradation.
Takeshi Kamakura, Kazuaki Kameda, Masahiko Manabe, Kan Torii, Yuki Sugiura, Masato Ohtsuka

Cell Death Discov· July 2024

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Targeted insertion of conditional expression cassettes into the mouse genome using the modified i-PITT.
Hiromi Miura, Ayaka Nakamura, Aki Kurosaki, Ai Kotani, Masaru Motojima, Masato Ohtsuka

BMC Genomics· June 2024

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Cross-contamination of CRISPR guides and other unrelated nucleotide sequences among commercial oligonucleotides.
Hiroshi Arakawa, Hiromi Miura, Rolen M Quadros, Masato Ohtsuka, Channabasavaiah B Gurumurthy

Nucleic Acids Res· April 2024

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Multiplexed genome editing by in vivo electroporation of Cas9 ribonucleoproteins effectively induces endometrial carcinoma in mice.
Ryosuke Kobayashi, Reika Kawabata-Iwakawa, Makoto Sugiyama, Tetsunari Oyama, Masato Ohtsuka

Int J Cancer· June 2023

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Bone marrow-derived fibroblast migration via periostin causes irreversible arthrogenic contracture after joint immobilization.
Hirotaka Iura, Kazu Kobayakawa, Hirokazu Saiwai, Daijiro Konno, Masatake Tanaka, Masato Ohtsuka

FASEB J· May 2023

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Improved Genome Editing via Oviductal Nucleic Acids Delivery (i-GONAD): Protocol Steps and Additional Notes.
Masahiro Sato, Ayaka Nakamura, Marie Sekiguchi, Takashi Matsuwaki, Hiromi Miura, Masato Ohtsuka

Methods Mol Biol· April 2023

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Delivering mRNAs to mouse tissues using the SEND system.
Masato Ohtsuka, Jurai Imafuku, Shuho Hori, Aki Kurosaki, Ayaka Nakamura

bioRxiv· January 2023

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Prototype mouse models for researching SEND-based mRNA delivery and gene therapy.
Channabasavaiah B Gurumurthy, Rolen M Quadros, Masato Ohtsuka

Nat Protoc· October 2022

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Gender-Difference in Hair Length as Revealed by Crispr-Based Production of Long-Haired Mice with Dysfunctional FGF5 Mutations.
Ryo Takahashi, Gou Takahashi, Yuichi Kameyama, Masahiro Sato, Masato Ohtsuka

Int J Mol Sci· October 2022

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CRISPR-KRISPR: a method to identify on-target and random insertion of donor DNAs and their characterization in knock-in mice.
Masayuki Tanaka, Keiko Yokoyama, Hideki Hayashi, Sanae Isaki, Kanae Kitatani, Masato Ohtsuka

Genome Biol· October 2022

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Use of anti-inhibin monoclonal antibody for increasing the litter size of mouse strains and its application to in vivo-genome editing technology†.
Ayumi Hasegawa, Keiji Mochida, Ayaka Nakamura, Rico Miyagasako, Masato Ohtsuka

Biol Reprod· August 2022

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Dll1 Can Function as a Ligand of Notch1 and Notch2 in the Thymic Epithelium.
Ken-Ichi Hirano, Hiroyuki Hosokawa, Takashi Yahata, Kiyoshi Ando, Masayuki Tanaka, Masato Ohtsuka

Front Immunol· April 2022

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Cyclin D1 Binding Protein 1 Responds to DNA Damage through the ATM-CHK2 Pathway.
Yusuke Niwa, Kenya Kamimura, Kohei Ogawa, Chiyumi Oda, Yuto Tanaka, Masato Ohtsuka

J Clin Med· February 2022

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GONAD: A new method for germline genome editing in mice and rats.
Masumi Namba, Tomoe Kobayashi, Takayuki Koyano, Mayumi Kohno, Masato Ohtsuka

Dev Growth Differ· October 2021

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Novel reporter mouse models useful for evaluating gene editing and for optimization of methods of delivering genome editing tools.
Hiromi Miura, Jurai Imafuku, Aki Kurosaki, Masahiro Sato, Yongjie Ma, Masato Ohtsuka

Mol Ther Nucleic Acids· June 2021

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Indirect podocyte injury manifested in a partial podocytectomy mouse model.
Masahiro Okabe, Kazuyoshi Yamamoto, Yoichi Miyazaki, Masaru Motojima, Masato Ohtsuka

Am J Physiol Renal Physiol· May 2021

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Response to correspondence on "Reproducibility of CRISPR-Cas9 methods for generation of conditional mouse alleles: a multi-center evaluation".
Channabasavaiah B Gurumurthy, Aidan R O'Brien, Rolen M Quadros, John Adams, Pilar Alcaide, Masato Ohtsuka

Genome Biol· April 2021

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Interleukin-11-expressing fibroblasts have a unique gene signature correlated with poor prognosis of colorectal cancer.
Takashi Nishina, Yutaka Deguchi, Daisuke Ohshima, Wakami Takeda, Masato Ohtsuka

Nat Commun· April 2021

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Designing and generating a mouse model: frequently asked questions.
Channabasavaiah B Gurumurthy, Thomas L Saunders, Masato Ohtsuka

J Biomed Res· March 2021

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