Publications by authors named "Massimo D'Apuzzo"

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Rapid cancer diagnosis using deep learning-powered label-free subcellular-resolution photoacoustic histology.
Byullee Park, Rui Cao, Yilin Luo, Cindy Liu, Yushun Zeng, Massimo D'Apuzzo

Sci Adv· November 2025

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Chlorotoxin-directed CAR T cell therapy for recurrent glioblastoma: Interim clinical experience demonstrating feasibility and safety.
Michael E Barish, Maryam Aftabizadeh, Jonathan Hibbard, M Suzette Blanchard, Julie R Ostberg, Massimo D'Apuzzo

Cell Rep Med· August 2025

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PSCA-CAR T cell therapy in metastatic castration-resistant prostate cancer: a phase 1 trial.
Tanya B Dorff, M Suzette Blanchard, Lauren N Adkins, Laura Luebbert, Neena Leggett, Massimo D'Apuzzo

Nat Med· June 2024

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Author Correction: Locoregional delivery of IL-13Rα2-targeting CAR-T cells in recurrent high-grade glioma: a phase 1 trial.
Christine E Brown, Jonathan C Hibbard, Darya Alizadeh, M Suzette Blanchard, Heini M Natri, Massimo D'Apuzzo

Nat Med· May 2024

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Locoregional delivery of IL-13Rα2-targeting CAR-T cells in recurrent high-grade glioma: a phase 1 trial.
Christine E Brown, Jonathan C Hibbard, Darya Alizadeh, M Suzette Blanchard, Heini M Natri, Massimo D'Apuzzo

Nat Med· April 2024

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Peritumoral Immune-suppressive Mechanisms Impede Intratumoral Lymphocyte Infiltration into Colorectal Cancer Liver versus Lung Metastases.
Jian Ye, Weihua Guo, Chongkai Wang, Colt A Egelston, Massimo D'Apuzzo

Cancer Res Commun· October 2023

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Expansion of endogenous T cells in CSF of pediatric CNS tumor patients undergoing locoregional delivery of IL13R〿2-targeting CAR T cells: an interim analysis.
Leo Wang, Angela Taravella Oill, M Blanchard, Melody Wu, Jonathan Hibbard, Massimo D'Apuzzo

Res Sq· October 2023

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Off-the-shelf, steroid-resistant, IL13Rα2-specific CAR T cells for treatment of glioblastoma.
Christine E Brown, Analiz Rodriguez, Joycelynne Palmer, Julie R Ostberg, Araceli Naranjo, Massimo D'Apuzzo

Neuro Oncol· August 2022

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Spatial organization of heterogeneous immunotherapy target antigen expression in high-grade glioma.
Michael E Barish, Lihong Weng, Dina Awabdeh, Yubo Zhai, Renate Starr, Massimo D'Apuzzo

Neoplasia· August 2022

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Immunotherapy-Based Neoadjuvant Treatment of Advanced Microsatellite Instability-High Gastric Cancer: A Case Series.
Louisa Liu, Yanghee Woo, Massimo D'Apuzzo, Laleh Melstrom, Mustafa Raoof

J Natl Compr Canc Netw· August 2022

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A Phase 2 Trial Combining Pembrolizumab and Palliative Radiation Therapy in Gastroesophageal Cancer to Augment Abscopal Immune Responses.
Joseph Chao, Ting-Fang He, Massimo D'Apuzzo, Yi-Jen Chen, Paul Frankel

Adv Radiat Oncol· September 2021

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Feasibility of intracerebrally administering multiple doses of genetically modified neural stem cells to locally produce chemotherapy in glioma patients.
Jana Portnow, Behnam Badie, M Suzette Blanchard, Julie Kilpatrick, Revathiswari Tirughana, Massimo D'Apuzzo

Cancer Gene Ther· April 2021

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Desmoplasia and oncogene driven acinar-to-ductal metaplasia are concurrent events during acinar cell-derived pancreatic cancer initiation in young adult mice.
Benjamin L Johnson, Marcela d'Alincourt Salazar, Sarah Mackenzie-Dyck, Massimo D'Apuzzo, Hung Ping Shih

PLoS One· March 2020

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A brainstem mass of Müllerian type Epithelial Origin without any primary cancer source.
Brian Fiani, Syed A Quadri, Mudassir Farooqui, Massimo D'Apuzzo, Robert J Rosser

J Clin Neurosci· January 2019

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Pituitary metastasis: a rare condition.
Aida Javanbakht, Massimo D'Apuzzo, Behnam Badie, Behrouz Salehian

Endocr Connect· October 2018

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Early Changes in Tumor Perfusion from T1-Weighted Dynamic Contrast-Enhanced MRI following Neural Stem Cell-Mediated Therapy of Recurrent High-Grade Glioma Correlate with Overall Survival.
Prativa Sahoo, Paul Frankel, Julie Ressler, Margarita Gutova, Alexander J Annala, Massimo D'Apuzzo

Stem Cells Int· March 2018

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Optimization of IL13Rα2-Targeted Chimeric Antigen Receptor T Cells for Improved Anti-tumor Efficacy against Glioblastoma.
Christine E Brown, Brenda Aguilar, Renate Starr, Xin Yang, Wen-Chung Chang, Massimo D'Apuzzo

Mol Ther· January 2018

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TLR9 expression and secretion of LIF by prostate cancer cells stimulates accumulation and activity of polymorphonuclear MDSCs.
Haejung Won, Dayson Moreira, Chan Gao, Priyanka Duttagupta, Xingli Zhao, Massimo D'Apuzzo

J Leukoc Biol· August 2017

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BarTeL, a Genetically Versatile, Bioluminescent and Granule Neuron Precursor-Targeted Mouse Model for Medulloblastoma.
Gregory M Shackleford, Xiang-He Shi, Kimberly S Swanson, Min Y Mahdi, Ignacio Gonzalez-Gomez, Massimo D'Apuzzo

PLoS One· July 2017

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Characterization of Arginase Expression in Glioma-Associated Microglia and Macrophages.
Ian Zhang, Darya Alizadeh, Junling Liang, Leying Zhang, Hang Gao, Massimo D'Apuzzo

PLoS One· July 2017

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Neural Stem Cell-Based Anticancer Gene Therapy: A First-in-Human Study in Recurrent High-Grade Glioma Patients.
Jana Portnow, Timothy W Synold, Behnam Badie, Revathiswari Tirughana, Simon F Lacey, Massimo D'Apuzzo

Clin Cancer Res· June 2017

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Regression of Glioblastoma after Chimeric Antigen Receptor T-Cell Therapy.
Christine E Brown, Darya Alizadeh, Renate Starr, Lihong Weng, Jamie R Wagner, Massimo D'Apuzzo

N Engl J Med· December 2016

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Evaluation of innate and adaptive immunity contributing to the antitumor effects of PD1 blockade in an orthotopic murine model of pancreatic cancer.
Marcela D'Alincourt Salazar, Edwin R Manuel, Weimin Tsai, Massimo D'Apuzzo, Leanne Goldstein

Oncoimmunology· June 2016

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Downregulation of TLX induces TET3 expression and inhibits glioblastoma stem cell self-renewal and tumorigenesis.
Qi Cui, Su Yang, Peng Ye, E Tian, Guoqiang Sun, Massimo D'Apuzzo

Nat Commun· February 2016

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Salmonella-Based Therapy Targeting Indoleamine 2,3-Dioxygenase Coupled with Enzymatic Depletion of Tumor Hyaluronan Induces Complete Regression of Aggressive Pancreatic Tumors.
Edwin R Manuel, Jeremy Chen, Massimo D'Apuzzo, Melanie G Lampa, Teodora I Kaltcheva

Cancer Immunol Res· September 2015

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