Publications by authors named "Mathangi Gopalakrishnan"

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Leveraging Model Integrated Bioequivalence (MIBE) to Address Regulatory Concerns and Waive Repeat Bioequivalence Studies-A Case Study with Clopidogrel.
Mathangi Gopalakrishnan, Adithya Karthik Bhattiprolu, Joga Gobburu, Rajkumar Boddu, Veena Kambam

J Clin Pharmacol· January 2026

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A real-world data-driven approach to optimizing enoxaparin dosing in burn patients.
Babajide Shenkoya, Venkata Yellepeddi, Ann Marie B Prazak, Mathangi Gopalakrishnan

Br J Clin Pharmacol· November 2025

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Predictors of Anemia Intolerance for Real-Time Transfusion Decision-Making During Resuscitation of Trauma Subjects: A Machine Learning Approach Using Heart Rate Variability.
Mathangi Gopalakrishnan, Jie Chen, Rahul Goyal, Shiming Yang, Chein-I Chang

Crit Care Explor· October 2025

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Micronutrient Biomarker Selection and Assay Methods and Performance in Double-Blind, Randomized, Controlled Micronutrient Dose Response (MiNDR) Trials among Women of Reproductive Age and Pregnant Women in Rural Bangladesh.
Sulagna Bandyopadhyay, Anjan Kumar Roy, Sarah Baker, Katherine K Stephenson, Ximing Ge, Mathangi Gopalakrishnan

Curr Dev Nutr· October 2025

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Pharmacologic Inhibition of Macrophage Triglyceride Biosynthesis Pathways Does Not Improve Mycobacterium tuberculosis Control in Infected Mice.
Jennie Ruelas Castillo, Valentina Guerrini, Darla Quijada, Styliani Karanika, Pranita Neupane, Mathangi Gopalakrishnan

J Infect Dis· June 2025

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Longitudinal patterns of loss of independence in Parkinson disease.
Tsung-Ying Lee, Lisa M Shulman, Ann L Gruber-Baldini, Julia F Slejko, Mathangi Gopalakrishnan

Neurodegener Dis Manag· June 2025

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Early human milk feeding: Relationship to intestinal barrier maturation and postnatal growth.
Lisa Roskes, Athanasios Chamzas, Bing Ma, Alexandre E Medina, Mathangi Gopalakrishnan

Pediatr Res· May 2025

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Micronutrient dose response (MiNDR) study among women of reproductive age and pregnant women in rural Bangladesh: study protocol for double-blind, randomised, controlled trials.
Towfida Jahan Siddiqua, Kerry J Schulze, Sm Tafsir Hasan, Khalid Bin Ahsan, Sulagna Bandyopadhyay, Mathangi Gopalakrishnan

BMJ Open· January 2025

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Effect of neonatal intensive care unit design on infants with Neonatal Opioid Withdrawal Syndrome.
Katherine Nyman, Elyse Decker, Kristin Ronan, Mathangi Gopalakrishnan, Dina El-Metwally

J Neonatal Perinatal Med· January 2025

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Comparative effectiveness of olodaterol/tiotropium and vilanterol/umeclidinium among COPD patients: a high-dimensional propensity score matched new user cohort study in a US medicare population.
Chintal H Shah, Robert M Reed, Linda Wastila, Eberechukwu Onukwugha, Mathangi Gopalakrishnan

Expert Rev Respir Med· December 2024

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Physiologically based pharmacokinetic modeling of long-acting extended-release naltrexone in pregnant women with opioid use disorder.
Babajide Shenkoya, Mathangi Gopalakrishnan, Ahizechukwu C Eke

CPT Pharmacometrics Syst Pharmacol· November 2024

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Exposure-Response Modeling in Adults and Adolescents With Schizophrenia to Support the Extrapolation of Brexpiprazole Efficacy to Adolescents.
Xiaofeng Wang, Mathangi Gopalakrishnan, Benjamin Rich, Jogarao V Gobburu, Frank Larsen

J Clin Pharmacol· October 2024

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Intergenerational transmission of sucralose and acesulfame-potassium from mothers to their infants via human milk: a pharmacokinetic study.
Allison C Sylvetsky, Janae T Kuttamperoor, Brooke Langevin, Jeanne Murphy, Kathleen F Arcaro, Mathangi Gopalakrishnan

Am J Clin Nutr· October 2024

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Optimizing tacrolimus dosing in Hispanic renal transplant patients: insights from real-world data.
Athanasios Chamzas, Eglis Tellez, Andrew SyBing, Jogarao V S Gobburu, Mathangi Gopalakrishnan

Front Pharmacol· September 2024

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Project Optimus Elicits the "Holistic" Benefits of PK/PD Modeling of Immunotherapy.
Mathangi Gopalakrishnan, Rodabe N Amaria

Clin Cancer Res· July 2024

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Impact of Delayed Cord Clamping on Red Blood Cell Transfusion and Related Outcomes in Very Low Birth Weight Infants.
Mayuri Patel, Mathangi Gopalakrishnan, Sripriya Sundararajan

Am J Perinatol· May 2024

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Pharmacokinetic Modeling Using Real-World Data to Optimize Unfractionated Heparin Dosing in Pediatric Patients on Extracorporeal Membrane Oxygenation and Evaluate Target Achievement-Clinical Outcomes Relationship.
Ahmed M Salem, Trey Smith, Jacob Wilkes, David K Bailly, Caroline Heyrend, Mathangi Gopalakrishnan

J Clin Pharmacol· January 2024

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Pharmacokinetics and Biodistribution of 16,16 dimethyl Prostaglandin E2 in Non-Irradiated and Irradiated Mice and Non-Irradiated Non-Human Primates.
Brooke Langevin, Pratibha Singh, P Artur Plett, Carol H Sampson, Andi Masters, Mathangi Gopalakrishnan

Radiat Res· January 2024

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DON in pediatric cerebral malaria, a phase I/IIA dose-escalation safety study: study protocol for a clinical trial.
Nginache Nampota-Nkomba, Osward M Nyirenda, Jane Mallewa, Yamikani Chimalizeni, Nettie Dzabala, Mathangi Gopalakrishnan

Trials· January 2024

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The MILK study: Investigating intergenerational transmission of low-calorie sweeteners in breast milk.
Brooke Langevin, Mathangi Gopalakrishnan, Janae Kuttamperoor, John Van Den Anker, Jeanne Murphy

Contemp Clin Trials Commun· December 2023

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Direct Medical Costs of COPD in the USA: An Analysis of the Medical Expenditure Panel Survey 2017-2018.
Chintal H Shah, Robert M Reed, Linda Wastila, Eberechukwu Onukwugha, Mathangi Gopalakrishnan

Appl Health Econ Health Policy· November 2023

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Predicting Heterogeneity in Patient Response to Morphine Treatment for Neonatal Opioid Withdrawal Syndrome.
Daniel Smolyak, Elizabeth M Humphries, Abhinav Parikh, Mathangi Gopalakrishnan, Fulden Aycan

Clin Pharmacol Ther· November 2023

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Is There a Need for a Dedicated Pharmacokinetic Trial for a Drug in Obese Populations? A Drug Prioritization Decision Tree Framework.
Brooke Langevin, Jogarao V S Gobburu, Mathangi Gopalakrishnan

J Clin Pharmacol· November 2023

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Predicting Maternal and Infant Tetrahydrocannabinol Exposure in Lactating Cannabis Users: A Physiologically Based Pharmacokinetic Modeling Approach.
Babajide Shenkoya, Venkata Yellepeddi, Katrina Mark, Mathangi Gopalakrishnan

Pharmaceutics· October 2023

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Model-based approach to identify predictors of paclitaxel-induced myelosuppression in "real-world" administration.
Ahmed M Salem, Erik Dvergsten, Sanja Karovic, Michael L Maitland, Mathangi Gopalakrishnan

CPT Pharmacometrics Syst Pharmacol· July 2023

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