Publications by authors named "Mathew Clement"

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Human Cytomegalovirus Immune Evasion of Natural Killer Cells: A Virus for All Seasons?
Hannah Preston, Rowan Casey, Elizabeth Ferris, Lauren Kerr-Jones, Lauren Jones, Mathew Clement

Pathogens· June 2025

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Cytomegalovirus-induced peroxynitrite promotes virus entry and contributes to pathogenesis in a murine model of infection.
Pragati S Amratia, Lauren E Kerr-Jones, Lucy Chapman, Morgan Marsden, Mathew Clement

mBio· August 2024

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Acquisition of suppressive function by conventional T cells limits antitumor immunity upon T depletion.
Sarah K Whiteside, Francis M Grant, Giorgia Alvisi, James Clarke, Leqi Tang, Mathew Clement

Sci Immunol· December 2023

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The association of microbial infection and adaptive immune cell activation in Alzheimer's disease.
Mathew Clement

Discov Immunol· September 2023

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High-affinity CD8 variants enhance the sensitivity of pMHCI antigen recognition via low-affinity TCRs.
Lea Knezevic, Tassilo L A Wachsmann, Ore Francis, Tamsin Dockree, John S Bridgeman, Mathew Clement

J Biol Chem· August 2023

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Inhibitory IL-10-producing CD4 T cells are T-bet-dependent and facilitate cytomegalovirus persistence via coexpression of arginase-1.
Mathew Clement, Kristin Ladell, Kelly L Miners, Morgan Marsden, Lucy Chapman

Elife· July 2023

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Optimal CD8 T-cell memory formation following subcutaneous cytomegalovirus infection requires virus replication but not early dendritic cell responses.
Sandra Dimonte, Silvia Gimeno-Brias, Morgan Marsden, Lucy Chapman, Pragati Sabberwal, Mathew Clement

Immunology· October 2021

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CD8 coreceptor-mediated focusing can reorder the agonist hierarchy of peptide ligands recognized via the T cell receptor.
Mathew Clement, Lea Knezevic, Tamsin Dockree, James E McLaren, Kristin Ladell

Proc Natl Acad Sci U S A· July 2021

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IRF5 Promotes Influenza Virus-Induced Inflammatory Responses in Human Induced Pluripotent Stem Cell-Derived Myeloid Cells and Murine Models.
Jessica L Forbester, Mathew Clement, Dannielle Wellington, Amy Yeung, Sandra Dimonte

J Virol· April 2020

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Cytokine-Mediated Induction and Regulation of Tissue Damage During Cytomegalovirus Infection.
Mathew Clement, Ian R Humphreys

Front Immunol· January 2020

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The protective effect of inflammatory monocytes during systemic C. albicans infection is dependent on collaboration between C-type lectin-like receptors.
Aiysha Thompson, Luke C Davies, Chia-Te Liao, Diogo M da Fonseca, James S Griffiths, Mathew Clement

PLoS Pathog· June 2019

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IL-33 Augments Virus-Specific Memory T Cell Inflation and Potentiates the Efficacy of an Attenuated Cytomegalovirus-Based Vaccine.
James E McLaren, Mathew Clement, Morgan Marsden, Kelly L Miners, Sian Llewellyn-Lacey

J Immunol· February 2019

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Interferon lambda is required for interferon gamma-expressing NK cell responses but does not afford antiviral protection during acute and persistent murine cytomegalovirus infection.
Silvia Gimeno Brias, Morgan Marsden, Jessica Forbester, Mathew Clement, Cordelia Brandt

PLoS One· December 2018

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Peptide mimic for influenza vaccination using nonnatural combinatorial chemistry.
John J Miles, Mai Ping Tan, Garry Dolton, Emily Sj Edwards, Sarah Ae Galloway, Mathew Clement

J Clin Invest· April 2018

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Divergent roles for antigenic drive in the aetiology of primary versus dasatinib-associated CD8 TCR-Vβ expansions.
Anna Lissina, James E McLaren, Mette Ilander, Emma I Andersson, Catherine S Lewis, Mathew Clement

Sci Rep· February 2018

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NBEAL2 is required for neutrophil and NK cell function and pathogen defense.
John M Sowerby, David C Thomas, Simon Clare, Marion Espéli, Jose A Guerrero, Mathew Clement

J Clin Invest· September 2017

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The antiviral restriction factor IFN-induced transmembrane protein 3 prevents cytokine-driven CMV pathogenesis.
Maria A Stacey, Simon Clare, Mathew Clement, Morgan Marsden, Juneid Abdul-Karim

J Clin Invest· April 2017

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CD8 T-cell specificity is compromised at a defined MHCI/CD8 affinity threshold.
Tamsin Dockree, Christopher J Holland, Mathew Clement, Kristin Ladell, James E McLaren

Immunol Cell Biol· January 2017

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Structural Mechanism Underpinning Cross-reactivity of a CD8+ T-cell Clone That Recognizes a Peptide Derived from Human Telomerase Reverse Transcriptase.
David K Cole, Hugo A van den Berg, Angharad Lloyd, Michael D Crowther, Konrad Beck, Mathew Clement

J Biol Chem· January 2017

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Cytomegalovirus-Specific IL-10-Producing CD4+ T Cells Are Governed by Type-I IFN-Induced IL-27 and Promote Virus Persistence.
Mathew Clement, Morgan Marsden, Maria A Stacey, Juneid Abdul-Karim, Silvia Gimeno Brias

PLoS Pathog· December 2016

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Targeted suppression of autoreactive CD8 T-cell activation using blocking anti-CD8 antibodies.
Mathew Clement, James A Pearson, Stephanie Gras, Hugo A van den Berg, Anya Lissina

Sci Rep· October 2016

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Identification of human viral protein-derived ligands recognized by individual MHCI-restricted T-cell receptors.
Barbara Szomolay, Jie Liu, Paul E Brown, John J Miles, Mathew Clement

Immunol Cell Biol· July 2016

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IL-27 Induced by Select Candida spp. via TLR7/NOD2 Signaling and IFN-β Production Inhibits Fungal Clearance.
Emmanuel C Patin, Adam V Jones, Aiysha Thompson, Mathew Clement, Chia-Te Liao

J Immunol· July 2016

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Naive CD8⁺ T-cell precursors display structured TCR repertoires and composite antigen-driven selection dynamics.
Michelle A Neller, Kristin Ladell, James E McLaren, Katherine K Matthews, Emma Gostick, Mathew Clement

Immunol Cell Biol· August 2015

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Cellular-level versus receptor-level response threshold hierarchies in T-cell activation.
Hugo A van den Berg, Kristin Ladell, Kelly Miners, Bruno Laugel, Sian Llewellyn-Lacey, Mathew Clement

Front Immunol· September 2013

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