Publications by authors named "Mathew Coban"

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Therapeutic potential of inhibitors of gelatinases MMP-2 and MMP-9 for the treatment of breast cancer.
Alireza Shoari, Mathew A Coban, Evette S Radisky

FEBS J· November 2025

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Dynamicasome-a molecular dynamics-guided and AI-driven pathogenicity prediction catalogue for all genetic mutations.
Naeyma N Islam, Mathew A Coban, Jessica M Fuller, Caleb Weber, Rohit Chitale

Commun Biol· July 2025

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Directed evolution of metalloproteinase inhibitor TIMP-1 for selective inhibition of MMP-9 exploits catalytic and fibronectin domain interactions.
Alireza Shoari, Mathew A Coban, Alexandra Hockla, Arlinda Rezhdo, Alexandra M Dimesa

J Biol Chem· June 2025

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Targeting Invasion: The Role of MMP-2 and MMP-9 Inhibition in Colorectal Cancer Therapy.
Alireza Shoari, Arghavan Ashja Ardalan, Alexandra M Dimesa, Mathew A Coban

Biomolecules· December 2024

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Structural and Functional Characterization of the Most Frequent Pathogenic PRKN Substitution p.R275W.
Bernardo A Bustillos, Liam T Cocker, Mathew A Coban, Caleb A Weber, Jenny M Bredenberg

Cells· September 2024

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Structure and computation-guided yeast surface display for the evolution of TIMP-based matrix metalloproteinase inhibitors.
Alireza Shoari, Ghazaleh Khalili-Tanha, Mathew A Coban, Evette S Radisky

Front Mol Biosci· November 2023

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Statistical Mechanics Metrics in Pairing and Parsing In Silico and Phenotypic Data of a Novel Genetic NFκB1 (c.T638A) Variant.
Eman N Chaudhri, Jessica M Abbott, Naeyma N Islam, Caleb A Weber, Mathew A Coban

Genes (Basel)· September 2023

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Substitution of PINK1 Gly411 modulates substrate receptivity and turnover.
Fabienne C Fiesel, Dominika Fričová, Caleb S Hayes, Mathew A Coban, Roman Hudec

Autophagy· June 2023

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Unveiling an indole alkaloid diketopiperazine biosynthetic pathway that features a unique stereoisomerase and multifunctional methyltransferase.
Garrett Deletti, Sajan D Green, Caleb Weber, Kristen N Patterson, Swapnil S Joshi, Mathew Coban

Nat Commun· May 2023

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Activity-based protein profiling reveals active serine proteases that drive malignancy of human ovarian clear cell carcinoma.
Christine Mehner, Alexandra Hockla, Mathew Coban, Benjamin Madden, Rosendo Estrada

J Biol Chem· August 2022

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Engineering of tissue inhibitor of metalloproteinases TIMP-1 for fine discrimination between closely related stromelysins MMP-3 and MMP-10.
Maryam Raeeszadeh-Sarmazdeh, Mathew Coban, Shivansh Mahajan, Alexandra Hockla, Banumathi Sankaran

J Biol Chem· March 2022

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Structural And Computational Perspectives of Selectively Targeting Mutant Proteins.
Mathew A Coban, Sarah Fraga, Thomas R Caulfield

Curr Drug Discov Technol· December 2021

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Attacking COVID-19 Progression Using Multi-Drug Therapy for Synergetic Target Engagement.
Mathew A Coban, Juliet Morrison, Sushila Maharjan, David Hyram Hernandez Medina, Wanlu Li

Biomolecules· May 2021

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Targeting an autocrine IL-6-SPINK1 signaling axis to suppress metastatic spread in ovarian clear cell carcinoma.
Christine Mehner, Erin Miller, Alexandra Hockla, Mathew Coban, S John Weroha

Oncogene· October 2020

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A Virtual Screening Platform Identifies Chloroethylagelastatin A as a Potential Ribosomal Inhibitor.
Thomas R Caulfield, Karen E Hayes, Yushi Qiu, Mathew Coban, Joon Seok Oh

Biomolecules· October 2020

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Structural Models for the Dynamic Effects of Loss-of-Function Variants in the Human SIM1 Protein Transcriptional Activation Domain.
Mathew A Coban, Patrick R Blackburn, Murray L Whitelaw, Mieke M van Haelst, Paldeep S Atwal

Biomolecules· September 2020

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