Publications by authors named "Mathew Eapen"

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The addition of collagenase to BromAc for the management of inoperable pseudomyxoma peritonei -  results.
Carissa Vici, Mathew Eapen, Pooja Narang, David L Morris

Pleura Peritoneum· December 2025

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Epithelial-to-mesenchymal transition is an active process in the large airways of patients with asthma-COPD overlap and partially abrogated by inhaled corticosteroid treatment: a bronchoscopy endobronchial biopsy study.
Surajit Dey, Wenying Lu, Prabuddha S Pathinayake, Maddison Waters, Greg Haug, Mathew Suji Eapen

Front Immunol· June 2025

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Antiviral effect of Bromelain combined with acetylcysteine against SARS-CoV-2 Omicron variant.
Erik Vinicius de Sousa Reis, Linziane Lopes Ferreira, Felipe Alves Clarindo, Geovane Marques-Ferreira, Leonardo Camilo de Oliveira, Mathew Suji Eapen

Sci Rep· April 2025

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TGFβ1, SMAD and β-catenin in pulmonary arteries of smokers, patients with small airway disease and COPD: potential drivers of EndMT.
Prem Bhattarai, Wenying Lu, Ashutosh Hardikar, Archana Vijay Gaikwad, Surajit Dey, Mathew S Eapen

Clin Sci (Lond)· September 2024

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Impact of Nebulized BromAc on Mucus Plug Clearance in a Mechanically Ventilated Ex Vivo Ovine Lung Model of Obstructive Respiratory Conditions.
Nicole Valle, Mathew Suji Eapen, Krishna Pillai, Richard Morris, Javed Akhter

Life (Basel)· September 2024

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Large airway wall vascularity in patients with asthma-COPD overlap: a bronchoscopy study.
Surajit Dey, Wenying Lu, Heinrich C Weber, Collin Chia, Prabuddha S Pathinayake, Mathew Suji Eapen

ERJ Open Res· July 2024

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Platelet Activating Factor Receptor and Intercellular Adhesion Molecule-1 Expression Increases in the Small Airway Epithelium and Parenchyma of Patients with Idiopathic Pulmonary Fibrosis: Implications for Microbial Pathogenesis.
Affan Mahmood Shahzad, Wenying Lu, Surajit Dey, Prem Bhattarai, Archana Vijay Gaikwad, Mathew Suji Eapen

J Clin Med· April 2024

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Differential expression of mast cells in the small airways and alveolar septa of current smokers and patients with small airway disease and COPD.
Mathew Suji Eapen, Wenying Lu, Surajit Dey, Collin Chia, Ashutosh Hardikar

ERJ Open Res· March 2024

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TGF-β1, pSmad-2/3, Smad-7, and β-Catenin Are Augmented in the Pulmonary Arteries from Patients with Idiopathic Pulmonary Fibrosis (IPF): Role in Driving Endothelial-to-Mesenchymal Transition (EndMT).
Archana Vijay Gaikwad, Mathew Suji Eapen, Surajit Dey, Prem Bhattarai, Affan Mahmood Shahzad

J Clin Med· February 2024

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Taming the SARS-CoV-2-mediated proinflammatory response with BromAc.
Geovane Marques Ferreira, Felipe Alves Clarindo, Ágata Lopes Ribeiro, Letícia Gomes-de-Pontes, Luciana Debortoli de Carvalho, Mathew Suji Eapen

Front Immunol· January 2024

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Endothelial to mesenchymal transition is an active process in smokers and patients with early COPD contributing to pulmonary arterial pathology.
Prem Bhattarai, Wenying Lu, Ashutosh Hardikar, Surajit Dey, Archana Vijay Gaikwad, Mathew Suji Eapen

ERJ Open Res· January 2024

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Epithelial-mesenchymal transition changes in nonsmall cell lung cancer patients with early COPD.
Wenying Lu, Mathew Suji Eapen, Ashutosh Hardikar, Collin Chia, Iain Robertson

ERJ Open Res· November 2023

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Airway inflammatory changes in the lungs of patients with asthma-COPD overlap (ACO): a bronchoscopy endobronchial biopsy study.
Surajit Dey, Wenying Lu, Greg Haug, Collin Chia, Josie Larby, Mathew Suji Eapen

Respir Res· September 2023

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Transforming growth factor-β1 and SMAD signalling pathway in the small airways of smokers and patients with COPD: potential role in driving fibrotic type-2 epithelial mesenchymal transition.
Samuel James Brake, Wenying Lu, Collin Chia, Greg Haug, Josie Larby, Mathew Suji Eapen

Front Immunol· July 2023

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Systemic alterations in neutrophils and their precursors in early-stage chronic obstructive pulmonary disease.
Theodore S Kapellos, Kevin Baßler, Wataru Fujii, Christina Nalkurthi, Anna C Schaar, Mathew S Eapen

Cell Rep· June 2023

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Endothelial-to-mesenchymal transition: a precursor to pulmonary arterial remodelling in patients with idiopathic pulmonary fibrosis.
Archana Vijay Gaikwad, Wenying Lu, Surajit Dey, Prem Bhattarai, Greg Haug, Mathew Suji Eapen

ERJ Open Res· March 2023

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Adverse roles of mast cell chymase-1 in COPD.
Gang Liu, Andrew G Jarnicki, Keshav R Paudel, Wenying Lu, Ridhima Wadhwa, Mathew S Eapen

Eur Respir J· December 2022

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Differential airway remodeling changes were observed in patients with asthma COPD overlap compared to patients with asthma and COPD alone.
Surajit Dey, Wenying Lu, Heinrich C Weber, Sally Young, Josie Larby, Mathew Suji Eapen

Am J Physiol Lung Cell Mol Physiol· October 2022

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Arterial remodelling in smokers and in patients with small airway disease and COPD: implications for lung physiology and early origins of pulmonary hypertension.
Prem Bhattarai, Wenying Lu, Archana Vijay Gaikwad, Surajit Dey, Collin Chia, Mathew Suji Eapen

ERJ Open Res· October 2022

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Containment strategies for COVID-19 in India: lessons from the second wave.
Purva Asrani, Keshav Tiwari, Mathew Suji Eapen, M D Imtaiyaz Hassan, Sukhwinder Singh Sohal

Expert Rev Anti Infect Ther· June 2022

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SARS-CoV-2 (COVID-19) Adhesion Site Protein Upregulation in Small Airways, Type 2 Pneumocytes, and Alveolar Macrophages of Smokers and COPD - Possible Implications for Interstitial Fibrosis.
Samuel James Brake, Mathew Suji Eapen, Kielan Darcy McAlinden, James Markos, Greg Haug

Int J Chron Obstruct Pulmon Dis· January 2022

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Angiotensin-Converting Enzyme 2 (ACE2), Transmembrane Peptidase Serine 2 (TMPRSS2), and Furin Expression Increases in the Lungs of Patients with Idiopathic Pulmonary Fibrosis (IPF) and Lymphangioleiomyomatosis (LAM): Implications for SARS-CoV-2 (COVID-19) Infections.
Wenying Lu, Mathew Suji Eapen, Gurpreet Kaur Singhera, James Markos, Greg Haug

J Clin Med· January 2022

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Vascular remodelling in idiopathic pulmonary fibrosis patients and its detrimental effect on lung physiology: potential role of endothelial-to-mesenchymal transition.
Archana Vijay Gaikwad, Wenying Lu, Surajit Dey, Prem Bhattarai, Collin Chia, Mathew Suji Eapen

ERJ Open Res· January 2022

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Anti-Inflammatory Activity of Fucoidan Extracts In Vitro.
Tauseef Ahmad, Mathew Suji Eapen, Muhammad Ishaq, Ah Young Park, Samuel S Karpiniec

Mar Drugs· December 2021

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Impact of Deleterious Mutations on Structure, Function and Stability of Serum/Glucocorticoid Regulated Kinase 1: A Gene to Diseases Correlation.
Mohamed F AlAjmi, Shama Khan, Arunabh Choudhury, Taj Mohammad, Saba Noor, Mathew Suji Eapen

Front Mol Biosci· November 2021

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