Publications by authors named "Mathias Dahlmann"

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MACC1 Expression in Colorectal Cancer Is Upregulated by Loss of Epigenetic Repression Under Oxidative Stress Condition.
Suchittra Phoyen, Mathias Dahlmann, Pia Herrmann, Chanchai Boonla, Ulrike Stein

Cell Biochem Funct· August 2025

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EPI-X4, a CXCR4 antagonist inhibits tumor growth in pancreatic cancer and lymphoma models.
Micah N Sagini, Michael Zepp, Ergül Eyol, Doaa M Ali, Svetlana Gromova, Mathias Dahlmann

Peptides· May 2024

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Establishment and Thorough Characterization of Xenograft (PDX) Models Derived from Patients with Pancreatic Cancer for Molecular Analyses and Chemosensitivity Testing.
Diana Behrens, Ulrike Pfohl, Theresia Conrad, Michael Becker, Bernadette Brzezicha, Mathias Dahlmann

Cancers (Basel)· December 2023

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Clinically relevant glioblastoma patient-derived xenograft models to guide drug development and identify molecular signatures.
Joshua Alcaniz, Lars Winkler, Mathias Dahlmann, Michael Becker, Andrea Orthmann

Front Oncol· April 2023

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Calcium-binding protein S100P is a new target gene of MACC1, drives colorectal cancer metastasis and serves as a prognostic biomarker.
Felicitas Schmid, Mathias Dahlmann, Hanna Röhrich, Dennis Kobelt, Jens Hoffmann

Br J Cancer· September 2022

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Combinatorial treatment with statins and niclosamide prevents CRC dissemination by unhinging the MACC1-β-catenin-S100A4 axis of metastasis.
Benedikt Kortüm, Harikrishnan Radhakrishnan, Fabian Zincke, Christoph Sachse, Susen Burock, Mathias Dahlmann

Oncogene· September 2022

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Core-Clock Genes Regulate Proliferation and Invasion via a Reciprocal Interplay with MACC1 in Colorectal Cancer Cells.
Alireza Basti, Deeksha Malhan, Malti Dumbani, Mathias Dahlmann, Ulrike Stein

Cancers (Basel)· July 2022

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MACC1-Induced Collective Migration Is Promoted by Proliferation Rather Than Single Cell Biomechanics.
Tim Hohmann, Urszula Hohmann, Mathias Dahlmann, Dennis Kobelt, Ulrike Stein

Cancers (Basel)· June 2022

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A Molecularly Characterized Preclinical Platform of Subcutaneous Renal Cell Carcinoma (RCC) Patient-Derived Xenograft Models to Evaluate Novel Treatment Strategies.
Dennis Gürgen, Michael Becker, Mathias Dahlmann, Susanne Flechsig, Elke Schaeffeler

Front Oncol· June 2022

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Combination of Wnt/β-Catenin Targets S100A4 and DKK1 Improves Prognosis of Human Colorectal Cancer.
Mathias Dahlmann, Anne Monks, Erik D Harris, Dennis Kobelt, Marc Osterland

Cancers (Basel)· December 2021

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Peritoneal metastasis of colorectal cancer (pmCRC): identification of predictive molecular signatures by a novel preclinical platform of matching pmCRC PDX/PD3D models.
Mathias Dahlmann, Guido Gambara, Bernadette Brzezicha, Oliver Popp, Eva Pachmayr

Mol Cancer· October 2021

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The newly identified MEK1 tyrosine phosphorylation target MACC1 is druggable by approved MEK1 inhibitors to restrict colorectal cancer metastasis.
Dennis Kobelt, Daniel Perez-Hernandez, Claudia Fleuter, Mathias Dahlmann, Fabian Zincke

Oncogene· August 2021

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A Bioinformatic Pipeline to Identify Biomarkers for Metastasis Formation from RNA Sequencing Data.
Mathias Dahlmann, Ulrike S Stein

Methods Mol Biol· June 2021

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MACC1 regulates clathrin-mediated endocytosis and receptor recycling of transferrin receptor and EGFR in colorectal cancer.
Francesca Imbastari, Mathias Dahlmann, Anje Sporbert, Camilla Ciolli Mattioli, Tommaso Mari

Cell Mol Life Sci· April 2021

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Small Ones to Fight a Big Problem-Intervention of Cancer Metastasis by Small Molecules.
Dennis Kobelt, Mathias Dahlmann, Malti Dumbani, Nazli Güllü, Benedikt Kortüm

Cancers (Basel)· June 2020

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MACC1 driven alterations in cellular biomechanics facilitate cell motility in glioblastoma.
Tim Hohmann, Urszula Hohmann, Marc R Kolbe, Mathias Dahlmann, Dennis Kobelt

Cell Commun Signal· June 2020

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Restoring Treatment Response in Colorectal Cancer Cells by Targeting MACC1-Dependent ABCB1 Expression in Combination Therapy.
Mathias Dahlmann, Rebecca Werner, Benedikt Kortüm, Dennis Kobelt, Wolfgang Walther

Front Oncol· April 2020

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Circulating MACC1 Transcripts in Glioblastoma Patients Predict Prognosis and Treatment Response.
Carsten Hagemann, Nikolas Neuhaus, Mathias Dahlmann, Almuth F Kessler, Dennis Kobelt

Cancers (Basel)· June 2019

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Pressurized intraperitoneal aerosol chemotherapy and its effect on gastric-cancer-derived peritoneal metastases: an overview.
Miguel Alberto, Andreas Brandl, Pankaj Kumar Garg, Safak Gül-Klein, Mathias Dahlmann

Clin Exp Metastasis· February 2019

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Expression of activating transcription factor 5 (ATF5) is increased in astrocytomas of different WHO grades and correlates with survival of glioblastoma patients.
Jonas Feldheim, Almuth F Kessler, Dominik Schmitt, Lara Wilczek, Thomas Linsenmann, Mathias Dahlmann

Onco Targets Ther· December 2018

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MACC1-the first decade of a key metastasis molecule from gene discovery to clinical translation.
Harikrishnan Radhakrishnan, Wolfgang Walther, Fabian Zincke, Dennis Kobelt, Francesca Imbastari, Mathias Dahlmann

Cancer Metastasis Rev· December 2018

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Statin and rottlerin small-molecule inhibitors restrict colon cancer progression and metastasis via MACC1.
Manisha Juneja, Dennis Kobelt, Wolfgang Walther, Cynthia Voss, Janice Smith, Mathias Dahlmann

PLoS Biol· June 2017

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S100A4 in Cancer Metastasis: Wnt Signaling-Driven Interventions for Metastasis Restriction.
Mathias Dahlmann, Dennis Kobelt, Wolfgang Walther, Giridhar Mudduluru, Ulrike Stein

Cancers (Basel)· June 2016

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Repositioning of drugs for intervention in tumor progression and metastasis: Old drugs for new targets.
Giridhar Mudduluru, Wolfgang Walther, Dennis Kobelt, Mathias Dahlmann, Christoph Treese

Drug Resist Updat· May 2016

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RNA Interference for Antimetastatic Therapy.
Mathias Dahlmann, Ulrike Stein

Methods Mol Biol· March 2016

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