Publications by authors named "Mathieu Simonin"

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LEF1 intragenic deletion induces a dominant-negative isoform and unveils a Wnt/β-catenin vulnerability in T-ALL.
Manon Delafoy, Mickaël F Bonnet, Etienne Lengliné, Agata Cieslak, Aurore Touzart, Mathieu Simonin

Blood· December 2025

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Prognostic impact of the PredicT-ALL classifier in the AALL0434 trial: a model combining NGS, MRD, and WBC at diagnosis.
Mathieu Simonin, Nicolas Boissel, Arnaud Petit, Charles G Mullighan, Stephen P Hunger

Blood Adv· October 2025

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Towards methylation-based redefinition of TAL1 positive T-cell acute lymphoblastic leukaemia (T-ALL).
Charlotte Smith, Guillaume Charbonnier, Mathieu Simonin, Estelle Balducci, Thomas Steimle

Leukemia· October 2025

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The watch-and-wait approach for patients with juvenile myelomonocytic leukemia: results of the French cohort.
Quentin Neven, Chloé Arfeuille, Aurélie Caye-Eude, Pauline Durand, Elodie Lainey, Mathieu Simonin

Blood· September 2025

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Surface pTα expression predicts LCK activation and preclinical synergy of LCK and JAK coinhibition in adult T-ALL.
Lucien Courtois, Antoine Pinton, Aurélie Cabannes-Hamy, Mathieu Simonin, Guillaume P Andrieu

Blood· June 2025

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Epigenetics-based stratification in pediatric T-ALL.
Mathieu Simonin, Aurore Touzart

Blood· May 2025

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Oncogenomic profiling in infant-toddler T-ALL identifies NKX2 family genes as drivers linked to favorable outcomes.
Manon Delafoy, Estelle Balducci, Mathieu Simonin, Antoine Pinton, Guillaume Charbonnier

Hemasphere· May 2025

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A metabolic synthetic lethality of phosphoinositide 3-kinase-driven cancer.
Guillaume P Andrieu, Mathieu Simonin, Aurélie Cabannes-Hamy, Etienne Lengliné, Ambroise Marçais

Nat Commun· March 2025

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Monocentric experience of venetoclax-based regimen in paediatric refractory and relapsed AML/MDS.
Sophie Cousson, Charlotte Calvo, Lauriane Goldwirt, Mathieu Simonin, Julie Roupret-Serzec

Br J Haematol· January 2025

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Classic Hodgkin Lymphoma: The LYSA pragmatic guidelines.
Cédric Rossi, Guillaume Manson, Amira Marouf, Aurélie Cabannes-Hamy, Emmanuelle Nicolas-Virelizier, Mathieu Simonin

Eur J Cancer· December 2024

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Excellent outcome of children/adolescents with primary mediastinal large B-cell lymphoma treated with a FAB/ LMB-based chemotherapy regimen with rituximab.
Marie Emilie Dourthe, Anne Auperin, Charlotte Rigaud, Melissa Barbati, Jacinthe Bonneau, Mathieu Simonin

Haematologica· November 2024

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NGS-based stratification refines the risk stratification in T-ALL and identifies a very-high-risk subgroup of patients.
Mathieu Simonin, Loïc Vasseur, Etienne Lengliné, Ludovic Lhermitte, Aurélie Cabannes-Hamy

Blood· October 2024

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Genomic imbalance analysis provides new insight into prognostic factors in adult and pediatric T-ALL.
Estelle Balducci, Mathieu Simonin, Nicolas Duployez, Thomas Steimlé, Marie-Emilie Dourthe

Blood· August 2024

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Role of IL-27 in Epstein-Barr virus infection revealed by IL-27RA deficiency.
Emmanuel Martin, Sarah Winter, Cécile Garcin, Kay Tanita, Akihiro Hoshino, Mathieu Simonin

Nature· April 2024

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Cost-effectiveness analysis alongside the inter-B-NHL ritux 2010 trial: rituximab in children and adolescents with B cell non-Hodgkin's lymphoma.
Béranger Lueza, Anne Aupérin, Charlotte Rigaud, Thomas G Gross, Marta Pillon, Mathieu Simonin

Eur J Health Econ· March 2024

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Key factors associated with 6-thioguanine and 6-methylmercaptopurine nucleotide concentrations in children treated by thiopurine for acute leukaemia and inflammatory bowel disease.
Tiphaine Adam de Beaumais, Simon Lorrain, Naura Mamhoudi, Mathieu Simonin, Christine Martinez Vinson

Br J Clin Pharmacol· January 2024

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PHF6-altered T-ALL Harbor Epigenetic Repressive Switch at Bivalent Promoters and Respond to 5-Azacitidine and Venetoclax.
Antoine Pinton, Lucien Courtois, Charlotte Doublet, Aurélie Cabannes-Hamy, Guillaume Andrieu, Mathieu Simonin

Clin Cancer Res· January 2024

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The oncogenetic landscape and clinical impact of alterations in adult and pediatric T-cell acute lymphoblastic leukemia.
Marie Emilie Dourthe, Guillaume P Andrieu, Amandine Potier, Estelle Balducci, Julie Guerder, Mathieu Simonin

Haematologica· November 2023

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[Update on acute leukemia of ambiguous lineage in 2023 - Recommendations of the French Society for Childhood and Adolescent Cancer and Leukemia (SFCE)].
Mathieu Simonin, Elodie Lainey, Fanny Rialland, Aurélie Caye-Eude, Yves Reguerre

Bull Cancer· October 2023

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[Strategy of the French Society of Childhood Cancer (SFCE) for pediatric nodular lymphocyte predominant lymphoma].
Marie Emilie Dourthe, Mathieu Simonin, Charlotte Rigaud, Stéphanie Haouy, Françoise Montravers

Bull Cancer· September 2023

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Efficacy and safety of crizotinib in ALK-positive systemic anaplastic large-cell lymphoma in children, adolescents, and adult patients: results of the French AcSé-crizotinib trial.
Laurence Brugières, Nathalie Cozic, Roch Houot, Charlotte Rigaud, David Sibon, Mathieu Simonin

Eur J Cancer· September 2023

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IL-7 receptor expression is frequent in T-cell acute lymphoblastic leukemia and predicts sensitivity to JAK inhibition.
Lucien Courtois, Aurélie Cabannes-Hamy, Rathana Kim, Marine Delecourt, Antoine Pinton, Mathieu Simonin

Blood· July 2023

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TREC mediated oncogenesis in human immature T lymphoid malignancies preferentially involves ZFP36L2.
Estelle Balducci, Thomas Steimlé, Charlotte Smith, Patrick Villarese, Mélanie Feroul, Mathieu Simonin

Mol Cancer· July 2023

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Impact of T-cell Receptor Status on Mutational Landscape and Outcome in T-ALL.
Marie Emilie Dourthe, Lucien Courtois, Guillaume P Andrieu, Mathieu Simonin, Aurore Touzart

Hemasphere· April 2023

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Harnessing the MYB-dependent TAL1 5'super-enhancer for targeted therapy in T-ALL.
Charlotte Smith, Aurore Touzart, Mathieu Simonin, Christine Tran-Quang, Guillaume Hypolite

Mol Cancer· January 2023

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