Publications by authors named "Mathijs Sanders"

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Distinct roles of Atf3, Zfp711 and Bcl6b in early embryonic hematopoietic and endothelial lineage specification.
Ridvan Cetin, Giulia Picco, Jente van Staalduinen, Eric Bindels, Remco Hoogenboezem, Mathijs A Sanders

Development· December 2025

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Patient-Derived Xenograft Models of Fanconi Anemia-Associated Head and Neck Cancer Identify Personalized Therapeutic Strategies.
Jennifer Grandis, Hua Li, Benjamin A Harrison, Andrew Lh Webster, Joanna Pucilowska, Mathijs A Sanders

J Clin Invest· December 2025

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Circulating tumor cells in myeloma are a compound biomarker for bone marrow high-risk genomic alterations and tumor load.
Cathelijne Fokkema, Luca Bertamini, Madelon M E de Jong, Sabrin Tahri, Davine Hofste Op Bruinink, Mathijs Arnoud Sanders

Blood· December 2025

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An inflammatory T-cell-stromal axis contributes to hematopoietic stem/progenitor cell failure and clonal evolution in human myelodysplastic syndrome.
Lanpeng Chen, Yujie Bian, Eline Pronk, Claire van Dijk, Tim V D van Tienhoven, Mathijs A Sanders

Nat Commun· November 2025

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G-quadruplexes as a source of vulnerability in BRCA2deficient granule cell progenitors and medulloblastoma.
Danielle L Keahi, Mathijs A Sanders, Matthew R Paul, Andrew L H Webster, Yin Fang

Proc Natl Acad Sci U S A· September 2025

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Transcriptional profiling directs the classification of acute leukemias of ambiguous lineage into AML, B-ALL, or T-ALL.
Roger Mulet-Lazaro, Anikó Sijs-Szabó, Remco M Hoogenboezem, Stanley van Herk, Carla Exalto, Mathijs A Sanders

Hemasphere· August 2025

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The bone marrow NK-cell profile predicts MRD negativity in patients with multiple myeloma treated with daratumumab-based therapy.
Charlotte L B M Korst, Sabrin Tahri, Carolien Duetz, Wassilis S C Bruins, A Vera de Jonge, Mathijs A Sanders

Blood· June 2025

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Hematological phenotypes in GATA2 deficiency syndrome arise from aging, maladaptation to proliferation, and somatic events.
Juncal Fernandez-Orth, Cansu Koyunlar, Julia M Weiss, Emanuele Gioacchino, Hans de Looper, Mathijs Sanders

Blood Adv· June 2025

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Double mutant DNMT3A AML: a unique subtype experiencing increased DNA damage and poor prognosis.
Emma L Boertjes, Sanne Massaar, Annelieke Zeilemaker, Jolinda Konijnenburg, Melissa Rijken, Mathijs A Sanders

Blood Adv· March 2025

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Combined plasma protein and memory T cell profiling discern IBD-patient-immunotypes related to intestinal disease and treatment outcomes.
Maud Heredia, Mohammed Charrout, Renz C W Klomberg, Martine A Aardoom, Maria M E Jongsma, Mathijs A Sanders

Mucosal Immunol· February 2025

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Single-cell DNA sequencing reveals pervasive positive selection throughout preleukemic evolution.
Gladys Poon, Aditi Vedi, Mathijs Sanders, Elisa Laurenti, Peter Valk

Cell Genom· February 2025

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Interferon gamma-mediated prevention of tumor progression in a mouse model of multiple myeloma.
Zoltán Kellermayer, Sabrin Tahri, Madelon M E de Jong, Natalie Papazian, Cathelijne Fokkema, Mathijs A Sanders

Hemasphere· December 2024

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The Fanconi anemia pathway induces chromothripsis and ecDNA-driven cancer drug resistance.
Justin L Engel, Xiao Zhang, Mingming Wu, Yan Wang, Jose Espejo Valle-Inclán, Mathijs A Sanders

Cell· October 2024

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The genomic basis of childhood T-lineage acute lymphoblastic leukaemia.
Petri Pölönen, Danika Di Giacomo, Anna Eames Seffernick, Abdelrahman Elsayed, Shunsuke Kimura, Mathijs A Sanders

Nature· August 2024

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G-quadruplexes are a source of vulnerability in deficient granule cell progenitors and medulloblastoma.
Danielle L Keahi, Mathijs A Sanders, Matthew R Paul, Andrew L H Webster, Yin Fang

bioRxiv· July 2024

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Widespread chromatin context-dependencies of DNA double-strand break repair proteins.
Xabier Vergara, Anna G Manjón, Marcel de Haas, Ben Morris, Ruben Schep, Mathijs A Sanders

Nat Commun· June 2024

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An IL-1β-driven neutrophil-stromal cell axis fosters a BAFF-rich protumor microenvironment in individuals with multiple myeloma.
Madelon M E de Jong, Cathelijne Fokkema, Natalie Papazian, Ágnes Czeti, Marjolein K Appelman, Mathijs A Sanders

Nat Immunol· May 2024

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A Single-Cell Taxonomy Predicts Inflammatory Niche Remodeling to Drive Tissue Failure and Outcome in Human AML.
Lanpeng Chen, Eline Pronk, Claire van Dijk, Yujie Bian, Jacqueline Feyen, Mathijs A Sanders

Blood Cancer Discov· September 2023

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Author Correction: Reliable detection of somatic mutations in solid tissues by laser-capture microdissection and low-input DNA sequencing.
Peter Ellis, Luiza Moore, Mathijs A Sanders, Timothy M Butler, Simon F Brunner

Nat Protoc· June 2023

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Gata2-regulated Gfi1b expression controls endothelial programming during endothelial-to-hematopoietic transition.
Cansu Koyunlar, Emanuele Gioacchino, Disha Vadgama, Hans de Looper, Joke Zink, Mathijs A Sanders

Blood Adv· May 2023

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Prognostic Value of -Internal Tandem Duplication Residual Disease in Acute Myeloid Leukemia.
Tim Grob, Mathijs A Sanders, Christian M Vonk, Franҫois G Kavelaars, Melissa Rijken

J Clin Oncol· February 2023

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APOBEC mutagenesis is a common process in normal human small intestine.
Yichen Wang, Philip S Robinson, Tim H H Coorens, Luiza Moore, Henry Lee-Six, Mathijs A Sanders

Nat Genet· February 2023

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Hematopoietic Cell Autonomous Disruption of Hematopoiesis in a Germline Loss-of-function Mouse Model of -FPD.
Martijn P T Ernst, Eline Pronk, Claire van Dijk, Paulina M H van Strien, Tim V D van Tienhoven, Mathijs A Sanders

Hemasphere· February 2023

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Genomic signature of Fanconi anaemia DNA repair pathway deficiency in cancer.
Andrew L H Webster, Mathijs A Sanders, Krupa Patel, Ralf Dietrich, Raymond J Noonan

Nature· December 2022

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Myeloid cells promote interferon signaling-associated deterioration of the hematopoietic system.
Jacqueline Feyen, Zhen Ping, Lanpeng Chen, Claire van Dijk, Tim V D van Tienhoven, Mathijs A Sanders

Nat Commun· December 2022

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