Publications by authors named "Matt Jacobsen"

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Points to consider regarding the use and implementation of virtual controls in nonclinical general toxicology studies.
Xavier Palazzi, Lennart T Anger, Theresa Boulineau, Armelle Grevot, Magali Guffroy, Matt Jacobsen

Regul Toxicol Pharmacol· June 2024

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Toxicologic Pathology Forum Opinion Piece: Use of Virtual Control Groups in Nonclinical Toxicity Studies: The Anatomic Pathology Perspective.
Armelle Grevot, Julie Boisclair, Magali Guffroy, Peter Hall, Gabriele Pohlmeyer-Esch, Matt Jacobsen

Toxicol Pathol· August 2023

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Utilizing Whole Slide Images for the Primary Evaluation and Peer Review of a GLP-Compliant Rodent Toxicology Study.
Matt Jacobsen, Arthur Lewis, James Baily, Alain Fraser, Dan Rudmann

Toxicol Pathol· August 2021

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Toxicologic Pathology Forum*: Opinion on Considerations for the Use of Whole Slide Images in GLP Pathology Peer Review.
Alys Bradley, Matt Jacobsen

Toxicol Pathol· February 2019

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Nonproliferative and Proliferative Lesions of the Ratand Mouse Special Sense Organs(Ocular [eye and glands], Olfactory and Otic).
Meg Ferrell Ramos, Julia Baker, Elke-Astrid Atzpodien, Ute Bach, Jacqueline Brassard, Matt Jacobsen

J Toxicol Pathol· July 2018

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Targeting of NAT10 enhances healthspan in a mouse model of human accelerated aging syndrome.
Gabriel Balmus, Delphine Larrieu, Ana C Barros, Casey Collins, Monica Abrudan, Matt Jacobsen

Nat Commun· April 2018

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Synthetic lethality between PAXX and XLF in mammalian development.
Gabriel Balmus, Ana C Barros, Paul W G Wijnhoven, Chloé Lescale, Hélène Lenden Hasse, Matt Jacobsen

Genes Dev· October 2016

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Target organ profiles in toxicity studies supporting human dosing: Does severity progress with longer duration of exposure?
Ruth Roberts, Richard Callander, Paul Duffy, Matt Jacobsen, Richard Knight

Regul Toxicol Pharmacol· December 2015

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Troglitazone metabolism and transporter effects in chimeric mice: a comparison between chimeric humanized and chimeric murinized FRG mice.
Kristin Samuelsson, Kathryn Pickup, Sunil Sarda, John R Foster, Kevin Randall, Matt Jacobsen

Xenobiotica· January 2014

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Analytic evaluation of a human ELISA kit for measurement of inhibin B in rat samples.
Michelle Coulson, Sue Bickerton, Catherine J Betts, Matt Jacobsen, Jane Stewart

Birth Defects Res B Dev Reprod Toxicol· February 2013

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Differential effect of troglitazone on the human bile acid transporters, MRP2 and BSEP, in the PXB hepatic chimeric mouse.
John R Foster, Matt Jacobsen, Gerry Kenna, Timothy Schulz-Utermoehl, Yoshio Morikawa

Toxicol Pathol· December 2012

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Evaluation of the pharmacokinetics, biotransformation and hepatic transporter effects of troglitazone in mice with humanized livers.
Timothy Schulz-Utermoehl, Sunil Sarda, John R Foster, Matt Jacobsen, J Gerry Kenna

Xenobiotica· June 2012

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AZD8055 is a potent, selective, and orally bioavailable ATP-competitive mammalian target of rapamycin kinase inhibitor with in vitro and in vivo antitumor activity.
Christine M Chresta, Barry R Davies, Ian Hickson, Tom Harding, Sabina Cosulich, Matt Jacobsen

Cancer Res· January 2010

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Formic acid excretion in rats and mice exposed to bromodichloromethane: a possible link to renal tubule cell proliferation in long-term studies.
Ted Lock, Lisa Cottrell, Tony Soames, Matt Jacobsen, Rebecca Williams

Arch Toxicol· July 2004

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