Publications by authors named "Matthew B O'Rourke"

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'Omics technologies for the elucidation of the molecular mechanisms related to carbapenem-resistant and extended spectrum β-lactamase-producing Klebsiellapneumoniae.
Breyer Woodland, Piklu Roy Chowdhury, Matthew B O'Rourke, Matthew P Padula

Talanta· January 2026

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Sample Preparation for Multi-Omics Analysis: Considerations and Guidance for Identifying the Ideal Workflow.
Breyer Woodland, Luke A Farrell, Lana Brockbals, Maria Rezcallah, Aiden Brennan, Matthew B O'Rourke

Proteomics· November 2025

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The Current Molecular and Cellular Landscape of Chronic Obstructive Pulmonary Disease (COPD): A Review of Therapies and Efforts towards Personalized Treatment.
Luke A Farrell, Matthew B O'Rourke, Matthew P Padula, Fernando Souza-Fonseca-Guimaraes, Gaetano Caramori

Proteomes· August 2024

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Reusing Peptide Spectral Reference Libraries to Discover Putative Plasma Biomarkers of Response to Cancer Chemotherapy.
Matthew B O'Rourke, Philip P Hansbro, Mark P Molloy

Methods Mol Biol· July 2024

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Optimised plasma sample preparation and LC-MS analysis to support large-scale proteomic analysis of clinical trial specimens: Application to the Fenofibrate Intervention and Event Lowering in Diabetes (FIELD) trial.
Matthew B O'Rourke, Andrzej S Januszewski, David R Sullivan, Imre Lengyel, Alan J Stewart

Proteomics Clin Appl· May 2023

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OXSR1 inhibits inflammasome activation by limiting potassium efflux during mycobacterial infection.
Elinor Hortle, Vi Lt Tran, Kathryn Wright, Angela Rm Fontaine, Natalia Pinello, Matthew B O'Rourke

Life Sci Alliance· September 2022

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Viral Biomarker Detection and Validation Using MALDI Mass Spectrometry Imaging (MSI).
Matthew B O'Rourke, Ben R Roediger, Christopher J Jolly, Ben Crossett, Matthew P Padula

Proteomes· September 2022

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Proteomic Analysis of Whole Blood Using Volumetric Absorptive Microsampling for Precision Medicine Biomarker Studies.
Mark P Molloy, Cameron Hill, Matthew B O'Rourke, Jason Chandra, Pascal Steffen

J Proteome Res· April 2022

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Matrix phase fractionation: Investigating the compromise between dynamic range of analyte extraction and spatial resolution in mass spectrometry imaging.
Matthew B O'Rourke, Barney Viengkhou, Caine C Smith, Lorenz Sonderegger, Matthew P Padula

Rapid Commun Mass Spectrom· June 2021

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Data independent acquisition of plasma biomarkers of response to neoadjuvant chemotherapy in pancreatic ductal adenocarcinoma.
Matthew B O'Rourke, Sumit Sahni, Jaswinder Samra, Anubhav Mittal, Mark P Molloy

J Proteomics· January 2021

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Quantitative Proteomic Profiling of Small Molecule Treated Mesenchymal Stem Cells Using Chemical Probes.
Jerran Santos, Sibasish Dolai, Matthew B O'Rourke, Fei Liu, Matthew P Padula

Int J Mol Sci· December 2020

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Reporting of Hybrid Data and the Difficulties with Cross-Discipline Research Techniques.
Matthew B O'Rourke, Matthew P Padula

Proteomes· November 2020

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Murine and related chapparvoviruses are nephro-tropic and produce novel accessory proteins in infected kidneys.
Quintin Lee, Matthew P Padula, Natalia Pinello, Simon H Williams, Matthew B O'Rourke

PLoS Pathog· January 2020

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An Inexpensive, simple calibration method for MALDI TOF/TOF systems.
Matthew B O'Rourke, Matthew P Padula

J Mass Spectrom· December 2019

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What is Normalization? The Strategies Employed in Top-Down and Bottom-Up Proteome Analysis Workflows.
Matthew B O'Rourke, Stephanie E L Town, Penelope V Dalla, Fiona Bicknell, Naomi Koh Belic

Proteomes· August 2019

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Higher Mass Accuracy MALDI-TOF/TOF Lipid Imaging of Human Brain Tissue in Alzheimer's Disease.
Matthew B O'Rourke, Caine C Smith, Suzanne M De La Monte, Greg T Sutherland, Matthew P Padula

Curr Protoc Mol Biol· April 2019

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Identification of Novel Natural Substrates of Fibroblast Activation Protein-alpha by Differential Degradomics and Proteomics.
Hui Emma Zhang, Elizabeth J Hamson, Maria Magdalena Koczorowska, Stefan Tholen, Sumaiya Chowdhury, Matthew B O'Rourke

Mol Cell Proteomics· January 2019

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An Atypical Parvovirus Drives Chronic Tubulointerstitial Nephropathy and Kidney Fibrosis.
Ben Roediger, Quintin Lee, Shweta Tikoo, Joanna C A Cobbin, James M Henderson, Matthew B O'Rourke

Cell· October 2018

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The quest for improved reproducibility in MALDI mass spectrometry.
Matthew B O'Rourke, Steven P Djordjevic, Matthew P Padula

Mass Spectrom Rev· March 2018

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The Effect of Collimating Lens Focusing on Laser Beam Shape in Matrix Assisted Laser Desorption/Ionization Mass Spectrometry (MALDI-MS).
Matthew B O'Rourke, Benjamin B A Raymond, Steven P Djordjevic, Matthew P Padula

J Am Soc Mass Spectrom· March 2018

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Optimal Preparation of Formalin Fixed Samples for Peptide Based Matrix Assisted Laser Desorption/Ionization Mass Spectrometry Imaging Workflows.
Matthew B O'Rourke, Matthew P Padula, Caine Smith, Priscilla Youssef, Stuart Cordwell

J Vis Exp· January 2018

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Analysis of formalin-fixed, paraffin-embedded (FFPE) tissue via proteomic techniques and misconceptions of antigen retrieval.
Matthew B O'Rourke, Matthew P Padula

Biotechniques· June 2017

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The Characterization of Laser Ablation Patterns and a New Definition of Resolution in Matrix Assisted Laser Desorption Ionization Imaging Mass Spectrometry (MALDI-IMS).
Matthew B O'Rourke, Benjamin B A Raymond, Matthew P Padula

J Am Soc Mass Spectrom· May 2017

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A Comprehensive Guide for Performing Sample Preparation and Top-Down Protein Analysis.
Matthew P Padula, Iain J Berry, Matthew B O Rourke, Benjamin B A Raymond, Jerran Santos

Proteomes· April 2017

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A new standard of visual data representation for imaging mass spectrometry.
Matthew B O'Rourke, Matthew P Padula

Proteomics Clin Appl· March 2017

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