Publications by authors named "Matthew Bowler"

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Structural and functional characterization of TgGSK3, a druggable kinase in Toxoplasma gondii.
Silvia Diaz-Martin, Christopher Swale, Valeria Bellini, Irina Dobrescu, Janine Wenker, Matthew Bowler

Nat Commun· November 2025

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Dual-specificity mitogen-activated protein kinase kinases can use ADP to phosphorylate MAP kinases invitro.
Pauline Juyoux, Jill von Velsen, Erika Pellegrini, Matthew W Bowler

J Biol Chem· September 2025

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An ISWI-related chromatin remodeller regulates stage-specific gene expression in Toxoplasma gondii.
Belen Pachano, Dayana C Farhat, Martina Shahinas, Jill von Velsen, Charlotte Corrao, Matthew W Bowler

Nat Microbiol· May 2025

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Current and future perspectives for structural biology at the Grenoble EPN campus: a comprehensive overview.
Andrew A McCarthy, Shibom Basu, Florent Bernaudat, Matthew P Blakeley, Matthew W Bowler

J Synchrotron Radiat· May 2025

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Metal fluorides-multi-functional tools for the study of phosphoryl transfer enzymes, a practical guide.
Erika Pellegrini, Pauline Juyoux, Jill von Velsen, Nicola J Baxter, Hugh R W Dannatt, Matthew W Bowler

Structure· February 2025

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Counter-diffusion studies of human transthyretin: the growth of high-quality crystals for X-ray and neutron crystallography.
Clare De'Ath, Mizar F Oliva, Martine Moulin, Matthew P Blakeley, Michael Haertlein, Matthew W Bowler

J Appl Crystallogr· February 2025

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Structure and dynamics of the active site of hen egg-white lysozyme from atomic resolution neutron crystallography.
Joao Ramos, Valerie Laux, Sax A Mason, Marie-Hélène Lemée, Matthew W Bowler

Structure· January 2025

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Metal fluorides-multi-functional tools for the study of phosphoryl transfer enzymes, a practical guide.
Erika Pellegrini, Pauline Juyoux, Jill von Velsen, Nicola J Baxter, Hugh R W Dannatt, Matthew W Bowler

Structure· October 2024

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In situ serial crystallography facilitates 96-well plate structural analysis at low symmetry.
Nicolas Foos, Jean Baptise Florial, Mathias Eymery, Jeremy Sinoir, Franck Felisaz, Matthew W Bowler

IUCrJ· September 2024

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High-confidence placement of low-occupancy fragments into electron density using the anomalous signal of sulfur and halogen atoms.
Shumeng Ma, Shymaa Damfo, Matthew W Bowler, Vitaliy Mykhaylyk, Frank Kozielski

Acta Crystallogr D Struct Biol· June 2024

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The assembly of the Mitochondrial Complex I Assembly complex uncovers a redox pathway coordination.
Lindsay McGregor, Samira Acajjaoui, Ambroise Desfosses, Melissa Saïdi, Maria Bacia-Verloop, Matthew W Bowler

Nat Commun· December 2023

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Architecture of the MKK6-p38α complex defines the basis of MAPK specificity and activation.
Pauline Juyoux, Ioannis Galdadas, Dorothea Gobbo, Jill von Velsen, Martin Pelosse, Matthew W Bowler

Science· September 2023

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High-Confidence Placement of Fragments into Electron Density Using Anomalous Diffraction-A Case Study Using Hits Targeting SARS-CoV-2 Non-Structural Protein 1.
Shumeng Ma, Vitaliy Mykhaylyk, Matthew W Bowler, Nikos Pinotsis, Frank Kozielski

Int J Mol Sci· July 2023

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The T structure of polycrystalline cubic human insulin.
Dimitris P Triandafillidis, Fotini Karavassili, Maria Spiliopoulou, Alexandros Valmas, Maria Athanasiadou, Matthew W Bowler

Acta Crystallogr D Struct Biol· May 2023

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Tyrosinase-Catalyzed Peptide Macrocyclization for mRNA Display.
Matthew C Fleming, Matthew M Bowler, Rodney Park, Konstantin I Popov, Albert A Bowers

J Am Chem Soc· May 2023

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Identification, binding, and structural characterization of single domain anti-PD-L1 antibodies inhibitory of immune regulatory proteins PD-1 and CD80.
Tara Kang-Pettinger, Kayleigh Walker, Richard Brown, Richard Cowan, Helena Wright, Matthew W Bowler

J Biol Chem· January 2023

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Enzymatic Macrolactamization of mRNA Display Libraries for Inhibitor Selection.
Matthew M Bowler, Marta Glavatskikh, Chad V Pecot, Dmitri Kireev, Albert A Bowers

ACS Chem Biol· January 2023

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Two Ligand-Binding Sites on SARS-CoV-2 Non-Structural Protein 1 Revealed by Fragment-Based X-ray Screening.
Shumeng Ma, Shymaa Damfo, Jiaqi Lou, Nikos Pinotsis, Matthew W Bowler

Int J Mol Sci· October 2022

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Altiratinib blocks and development by selectively targeting a spliceosome kinase.
Christopher Swale, Valeria Bellini, Matthew W Bowler, Nardella Flore, Marie-Pierre Brenier-Pinchart

Sci Transl Med· August 2022

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Structural insights into the substrate-bound condensation domains of non-ribosomal peptide synthetase AmbB.
Melissa-Jane Chu Yuan Kee, Sakshibeedu R Bharath, Sheena Wee, Matthew W Bowler, Jayantha Gunaratne

Sci Rep· March 2022

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In Vitro and In Vivo Inhibition of the Phosphopantetheinyl Transferase PptT by Amidinoureas.
Samantha Ottavi, Sarah M Scarry, John Mosior, Yan Ling, Julia Roberts, Matthew M Bowler

J Med Chem· February 2022

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Finding order in chaos - nanocrystals in amorphous protein gels.
Matthew W Bowler

Acta Crystallogr F Struct Biol Commun· November 2021

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Cross-Reactive SARS-CoV-2 Neutralizing Antibodies From Deep Mining of Early Patient Responses.
Georgia Bullen, Jacob D Galson, Gareth Hall, Pedro Villar, Lien Moreels, Matthew W Bowler

Front Immunol· July 2021

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A plant-like mechanism coupling m6A reading to polyadenylation safeguards transcriptome integrity and developmental gene partitioning in .
Dayana C Farhat, Matthew W Bowler, Guillaume Communie, Dominique Pontier, Lucid Belmudes

Elife· July 2021

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Structural and functional comparison of fumarylacetoacetate domain containing protein 1 in human and mouse.
Alexander K H Weiss, Andreas Naschberger, Elia Cappuccio, Christina Metzger, Lorenza Mottes, Matthew W Bowler

Biosci Rep· March 2020

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