Publications by authors named "Matthew Brecher"

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Structural interrogation of a trimeric prefusion RSV fusion protein vaccine candidate by a camelid nanobody.
Li Ma, Matthew Brecher, Allison Soufal, Tiziano Gaiotto, Sai Tian

Vaccine· May 2023

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Extensive recoding of dengue virus type 2 specifically reduces replication in primate cells without gain-of-function in Aedes aegypti mosquitoes.
Charles B Stauft, Sam H Shen, Yutong Song, Oleksandr Gorbatsevych, Emmanuel Asare, Matthew Brecher

PLoS One· February 2019

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Erythrosin B is a potent and broad-spectrum orthosteric inhibitor of the flavivirus NS2B-NS3 protease.
Zhong Li, Srilatha Sakamuru, Ruili Huang, Matthew Brecher, Cheri A Koetzner

Antiviral Res· February 2018

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Existing drugs as broad-spectrum and potent inhibitors for Zika virus by targeting NS2B-NS3 interaction.
Zhong Li, Matthew Brecher, Yong-Qiang Deng, Jing Zhang, Srilatha Sakamuru

Cell Res· August 2017

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Effects of Zika Virus Strain and Aedes Mosquito Species on Vector Competence.
Alexander T Ciota, Sean M Bialosuknia, Steven D Zink, Matthew Brecher, Dylan J Ehrbar

Emerg Infect Dis· July 2017

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A conformational switch high-throughput screening assay and allosteric inhibition of the flavivirus NS2B-NS3 protease.
Matthew Brecher, Zhong Li, Binbin Liu, Jing Zhang, Cheri A Koetzner

PLoS Pathog· May 2017

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DNA forms of arboviral RNA genomes are generated following infection in mosquito cell cultures.
Dilip K Nag, Matthew Brecher, Laura D Kramer

Virology· November 2016

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Novel Broad Spectrum Inhibitors Targeting the Flavivirus Methyltransferase.
Matthew Brecher, Hui Chen, Binbin Liu, Nilesh K Banavali, Susan A Jones

PLoS One· April 2016

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Identification and Characterization of Novel Broad-Spectrum Inhibitors of the Flavivirus Methyltransferase.
Matthew Brecher, Hui Chen, Zhong Li, Nilesh K Banavali, Susan A Jones

ACS Infect Dis· August 2015

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Coupling of Conformational Transitions in the N-terminal Domain of the 51-kDa FK506-binding Protein (FKBP51) Near Its Site of Interaction with the Steroid Receptor Proteins.
David M LeMaster, Sourajit M Mustafi, Matthew Brecher, Jing Zhang, Annie Héroux

J Biol Chem· June 2015

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Refolding of a fully functional flavivirus methyltransferase revealed that S-adenosyl methionine but not S-adenosyl homocysteine is copurified with flavivirus methyltransferase.
Matthew B Brecher, Zhong Li, Jing Zhang, Hui Chen, Qishan Lin

Protein Sci· January 2015

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Pfit is a structurally novel Crohn's disease-associated superantigen.
Lihui Liu, Hui Chen, Matthew B Brecher, Zhong Li, Bo Wei

PLoS Pathog· September 2014

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S-adenosyl-homocysteine is a weakly bound inhibitor for a flaviviral methyltransferase.
Hui Chen, Bing Zhou, Matthew Brecher, Nilesh Banavali, Susan A Jones

PLoS One· June 2014

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Structural basis of conformational transitions in the active site and 80's loop in the FK506-binding protein FKBP12.
Sourajit M Mustafi, Matthew Brecher, Jing Zhang, Hongmin Li, David M Lemaster

Biochem J· March 2014

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The flavivirus protease as a target for drug discovery.
Matthew Brecher, Jing Zhang, Hongmin Li

Virol Sin· December 2013

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Visualization of the two-step fusion process of the retrovirus avian sarcoma/leukosis virus by cryo-electron tomography.
Giovanni Cardone, Matthew Brecher, Juan Fontana, Dennis C Winkler, Carmen Butan

J Virol· November 2012

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Cathepsin cleavage potentiates the Ebola virus glycoprotein to undergo a subsequent fusion-relevant conformational change.
Matthew Brecher, Kathryn L Schornberg, Sue E Delos, Marnie L Fusco, Erica Ollmann Saphire

J Virol· January 2012

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The primed ebolavirus glycoprotein (19-kilodalton GP1,2): sequence and residues critical for host cell binding.
Derek Dube, Matthew B Brecher, Sue E Delos, Sean C Rose, Edward W Park

J Virol· April 2009

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Structures and mechanisms of viral membrane fusion proteins: multiple variations on a common theme.
Judith M White, Sue E Delos, Matthew Brecher, Kathryn Schornberg

Crit Rev Biochem Mol Biol· August 2008

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Cysteines flanking the internal fusion peptide are required for the avian sarcoma/leukosis virus glycoprotein to mediate the lipid mixing stage of fusion with high efficiency.
Sue E Delos, Matthew B Brecher, Zaoying Chen, Deborah C Melder, Mark J Federspiel

J Virol· March 2008

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Influenza virus pleiomorphy characterized by cryoelectron tomography.
Audray Harris, Giovanni Cardone, Dennis C Winkler, J Bernard Heymann, Matthew Brecher

Proc Natl Acad Sci U S A· December 2006

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