Publications by authors named "Matthew Burger"

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Benign Adenomyoepithelioma of the Breast: A Case Report and Review of Imaging Features.
Timea A Kovacs, Sophia N Mourad, Andrew Dakkak, Matthew Burger, Michele Edison

Cureus· April 2024

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Design, Synthesis, and In Vitro and In Vivo Evaluation of Cereblon Binding Bruton's Tyrosine Kinase (BTK) Degrader CD79b Targeted Antibody-Drug Conjugates.
Alan Zhang, Katherine Seiss, Laurent Laborde, Sebastian Palacio-Ramirez, Daniel Guthy, Matthew T Burger

Bioconjug Chem· February 2024

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Synthesis and Structure-Activity Relationship of Tetra-Substituted Cyclohexyl Diol Inhibitors of Proviral Insertion of Moloney Virus (PIM) Kinases.
Wooseok Han, Yu Ding, Zheng Chen, John L Langowski, Cornelia Bellamacina, Matthew T Burger

J Med Chem· December 2020

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Design and Discovery of -(3-(2-(2-Hydroxyethoxy)-6-morpholinopyridin-4-yl)-4-methylphenyl)-2-(trifluoromethyl)isonicotinamide, a Selective, Efficacious, and Well-Tolerated RAF Inhibitor Targeting RAS Mutant Cancers: The Path to the Clinic.
Savithri Ramurthy, Benjamin R Taft, Robert J Aversa, Paul A Barsanti, Matthew T Burger

J Med Chem· March 2020

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Interventions for Increasing the Quality of Preventive Care at a Free Clinic.
Matthew Burger, Marisa S Taddeo, Daniel Hushla, Magdalena Pasarica

Cureus· January 2020

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Innovative Teaching Strategies for Surgery Resident Education Sessions: Learner Preference of Slide-based Presentations Focused Study Guides.
Adebayo Awe, David H Ballard, Matthew Burger, Ashley Abrams, Gloria Caldito

Am Surg· December 2018

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Design and Discovery of N-(2-Methyl-5'-morpholino-6'-((tetrahydro-2H-pyran-4-yl)oxy)-[3,3'-bipyridin]-5-yl)-3-(trifluoromethyl)benzamide (RAF709): A Potent, Selective, and Efficacious RAF Inhibitor Targeting RAS Mutant Cancers.
Gisele A Nishiguchi, Alice Rico, Huw Tanner, Robert J Aversa, Benjamin R Taft, Matthew T Burger

J Med Chem· June 2017

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A Cold-Pole Enhancement in Mercury's Sodium Exosphere.
Timothy A Cassidy, William E McClintock, Rosemary M Killen, Menelaos Sarantos, Aimee W Merkel, Matthew H Burger

Geophys Res Lett· November 2016

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Human CD180 Transmits Signals via the PIM-1L Kinase.
Nicole Egli, Alexandra Zajonz, Matthew T Burger, Tamas Schweighoffer

PLoS One· June 2016

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Design, synthesis and structure activity relationship of potent pan-PIM kinase inhibitors derived from the pyridyl carboxamide scaffold.
Gisele A Nishiguchi, Matthew T Burger, Wooseok Han, Jiong Lan, Gordana Atallah

Bioorg Med Chem Lett· May 2016

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Discovery of imidazo[1,2-a]-pyridine inhibitors of pan-PI3 kinases that are efficacious in a mouse xenograft model.
Wooseok Han, Daniel L Menezes, Yongjin Xu, Mark S Knapp, Robert Elling, Matthew T Burger

Bioorg Med Chem Lett· February 2016

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Identification of N-(4-((1R,3S,5S)-3-Amino-5-methylcyclohexyl)pyridin-3-yl)-6-(2,6-difluorophenyl)-5-fluoropicolinamide (PIM447), a Potent and Selective Proviral Insertion Site of Moloney Murine Leukemia (PIM) 1, 2, and 3 Kinase Inhibitor in Clinical Trials for Hematological Malignancies.
Matthew T Burger, Gisele Nishiguchi, Wooseok Han, Jiong Lan, Robert Simmons

J Med Chem· November 2015

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Pan-PIM kinase inhibition provides a novel therapy for treating hematologic cancers.
Pablo D Garcia, John L Langowski, Yingyun Wang, Min Chen, Joseph Castillo, Matthew T Burger

Clin Cancer Res· April 2014

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Structure Guided Optimization, in Vitro Activity, and in Vivo Activity of Pan-PIM Kinase Inhibitors.
Matthew T Burger, Wooseok Han, Jiong Lan, Gisele Nishiguchi, Cornelia Bellamacina

ACS Med Chem Lett· December 2013

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Structure guided optimization of a fragment hit to imidazopyridine inhibitors of PI3K.
Sabina Pecchi, Zhi-Jie Ni, Wooseok Han, Aaron Smith, Jiong Lan, Matthew Burger

Bioorg Med Chem Lett· August 2013

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Identification and characterization of NVP-BKM120, an orally available pan-class I PI3-kinase inhibitor.
Sauveur-Michel Maira, Sabina Pecchi, Alan Huang, Matthew Burger, Mark Knapp

Mol Cancer Ther· February 2012

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Discovery of novel 3,5-disubstituted indole derivatives as potent inhibitors of Pim-1, Pim-2, and Pim-3 protein kinases.
Gisele A Nishiguchi, Gordana Atallah, Cornelia Bellamacina, Matthew T Burger, Yu Ding

Bioorg Med Chem Lett· November 2011

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Identification of NVP-BKM120 as a Potent, Selective, Orally Bioavailable Class I PI3 Kinase Inhibitor for Treating Cancer.
Matthew T Burger, Sabina Pecchi, Allan Wagman, Zhi-Jie Ni, Mark Knapp

ACS Med Chem Lett· October 2011

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Synthesis and in Vitro and in Vivo Evaluation of Phosphoinositide-3-kinase Inhibitors.
Matthew T Burger, Mark Knapp, Allan Wagman, Zhi-Jie Ni, Thomas Hendrickson

ACS Med Chem Lett· January 2011

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Mercury's complex exosphere: results from MESSENGER's third flyby.
Ronald J Vervack, William E McClintock, Rosemary M Killen, Ann L Sprague, Brian J Anderson, Matthew H Burger

Science· August 2010

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No sodium in the vapour plumes of Enceladus.
Nicholas M Schneider, Matthew H Burger, Emily L Schaller, Michael E Brown, Robert E Johnson

Nature· June 2009

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MESSENGER observations of Mercury's exosphere: detection of magnesium and distribution of constituents.
William E McClintock, Ronald J Vervack, E Todd Bradley, Rosemary M Killen, Nelly Mouawad, Matthew H Burger

Science· May 2009

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Synthesis and antibacterial activity of novel C12 ethyl ketolides.
Matthew T Burger, Christy Hiebert, Mehran Seid, Daniel T Chu, Lynn Barker

Bioorg Med Chem· August 2006

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Synthesis and antibacterial activity of novel C12 vinyl ketolides.
Matthew T Burger, Xiaodong Lin, Daniel T Chu, Christy Hiebert, Alice C Rico

J Med Chem· March 2006

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Improved Synthesis of Functionalized Podand Ionophores.
Matthew T. Burger, W. Clark Still

J Org Chem· January 1996

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