Publications by authors named "Matthew C Trudeau"

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Inhibition of hERG K channels by verapamil at physiological temperature: Implications for the CiPA initiative.
Ashley A Johnson, Matthew C Trudeau

J Pharmacol Toxicol Methods· December 2024

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Photoinhibition of the hERG potassium channel PAS domain by ultraviolet light speeds channel closing.
Sara J Codding, Matthew C Trudeau

Biophys J· August 2024

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A hydrophobic nexus at the heart of hERG K channel gating.
Matthew C Trudeau

Biophys J· July 2024

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Photo-crosslinking hERG channels causes a U.V.-driven, state-dependent disruption of kinetics and voltage dependence of activation.
Sara J Codding, Matthew C Trudeau

bioRxiv· January 2024

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The N-linker region of hERG1a upregulates hERG1b potassium channels.
Ashley A Johnson, Taylor R Crawford, Matthew C Trudeau

J Biol Chem· September 2022

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Conformation-sensitive antibody reveals an altered cytosolic PAS/CNBh assembly during hERG channel gating.
Carol A Harley, Ganeko Bernardo-Seisdedos, Whitney A Stevens-Sostre, David K Jones, Maria M Azevedo, Matthew C Trudeau

Proc Natl Acad Sci U S A· November 2021

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Gating and regulation of KCNH (ERG, EAG, and ELK) channels by intracellular domains.
Sara J Codding, Ashley A Johnson, Matthew C Trudeau

Channels (Austin)· December 2020

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Paul F. Cranefield Award to Anne E. Carlson.
Matthew C Trudeau

J Gen Physiol· September 2019

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The hERG potassium channel intrinsic ligand regulates N- and C-terminal interactions and channel closure.
Sara J Codding, Matthew C Trudeau

J Gen Physiol· April 2019

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Localization and functional consequences of a direct interaction between TRIOBP-1 and hERG proteins in the heart.
David K Jones, Ashley C Johnson, Elon C Roti Roti, Fang Liu, Rebecca Uelmen, Matthew C Trudeau

J Cell Sci· March 2018

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hERG1a and hERG1b potassium channel subunits directly interact and preferentially form heteromeric channels.
Beth A McNally, Zeus D Pendon, Matthew C Trudeau

J Biol Chem· December 2017

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Eag Domains Regulate LQT Mutant hERG Channels in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes.
Qiang-Ni Liu, Matthew C Trudeau

PLoS One· January 2016

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hERG 1b is critical for human cardiac repolarization.
David K Jones, Fang Liu, Ravi Vaidyanathan, L Lee Eckhardt, Matthew C Trudeau

Proc Natl Acad Sci U S A· December 2014

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Direct interaction of eag domains and cyclic nucleotide-binding homology domains regulate deactivation gating in hERG channels.
Elena C Gianulis, Qiangni Liu, Matthew C Trudeau

J Gen Physiol· October 2013

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Structure of the C-terminal region of an ERG channel and functional implications.
Tinatin I Brelidze, Elena C Gianulis, Frank DiMaio, Matthew C Trudeau, William N Zagotta

Proc Natl Acad Sci U S A· July 2013

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The eag domain regulates hERG channel inactivation gating via a direct interaction.
Ahleah S Gustina, Matthew C Trudeau

J Gen Physiol· February 2013

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Unlocking the mechanisms of HCN channel gating with locked-open and locked-closed channels.
Matthew C Trudeau

J Gen Physiol· November 2012

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HERG potassium channel regulation by the N-terminal eag domain.
Ahleah S Gustina, Matthew C Trudeau

Cell Signal· August 2012

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hERG1a N-terminal eag domain-containing polypeptides regulate homomeric hERG1b and heteromeric hERG1a/hERG1b channels: a possible mechanism for long QT syndrome.
Matthew C Trudeau, Lisa M Leung, Elon Roti Roti, Gail A Robertson

J Gen Physiol· December 2011

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Rescue of aberrant gating by a genetically encoded PAS (Per-Arnt-Sim) domain in several long QT syndrome mutant human ether-á-go-go-related gene potassium channels.
Elena C Gianulis, Matthew C Trudeau

J Biol Chem· June 2011

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hERG potassium channel gating is mediated by N- and C-terminal region interactions.
Ahleah S Gustina, Matthew C Trudeau

J Gen Physiol· March 2011

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A recombinant N-terminal domain fully restores deactivation gating in N-truncated and long QT syndrome mutant hERG potassium channels.
Ahleah S Gustina, Matthew C Trudeau

Proc Natl Acad Sci U S A· August 2009

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Emerging roles for ether-á-go-go-related gene potassium channels in the brain.
Paul D Shepard, Matthew C Trudeau

J Physiol· October 2008

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Dynamics of Ca2+-calmodulin-dependent inhibition of rod cyclic nucleotide-gated channels measured by patch-clamp fluorometry.
Matthew C Trudeau, William N Zagotta

J Gen Physiol· September 2004

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Calcium/calmodulin modulation of olfactory and rod cyclic nucleotide-gated ion channels.
Matthew C Trudeau, William N Zagotta

J Biol Chem· May 2003

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