Publications by authors named "Matthew Cottam"

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Effect of chemotherapy on passenger mutations in metastatic colorectal cancer.
Marium T Siddiqui, Matthew A Cottam, Muhammad Bilal Mirza, Keeli B Lewis, Kristen K Ciombor

Mol Oncol· November 2025

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Single cell RNA-sequencing suggests a novel lipid-associated mast cell population following weight cycling.
Munira Kapadia, Alexa M Betjemann, Matthew A Cottam, Mona Mashayekhi, Heidi J Silver

bioRxiv· September 2025

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Dehydration promotes intracellular lipid synthesis and accumulation.
Joshua S Carty, Jazlyn Selvasingh, Yvonne Zuchowski, Hyuck-Jin Nam, Clothilde Pénalva, Matthew A Cottam

bioRxiv· August 2025

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Comparison of Lean, Obese, and Weight-Loss Models Reveals TREM2 Deficiency Attenuates Breast Cancer Growth Uniquely in Lean Mice and Alters Clonal T-cell Populations.
Elysa W Pierro, Matthew A Cottam, Hanbing An, Brian D Lehmann, Jennifer A Pietenpol

Cancer Res· April 2025

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Incretin triple agonist retatrutide (LY3437943) alleviates obesity-associated cancer progression.
Sandesh J Marathe, Emily W Grey, Margaret S Bohm, Sydney C Joseph, Arvind V Ramesh, Matthew A Cottam

NPJ Metab Health Dis· March 2025

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Impaired oxidative phosphorylation drives primary tumor escape and metastasis.
Emily N Arner, Erin Q Jennings, Daniel R Crooks, Christopher J Ricketts, Melissa M Wolf, Matthew A Cottam

bioRxiv· January 2025

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Interrupting T cell memory ameliorates exaggerated metabolic response to weight cycling.
Jamie N Garcia, Matthew A Cottam, Alec S Rodriguez, Anwar F Hussein Agha, Nathan C Winn

bioRxiv· January 2025

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Transcriptomic Plasticity of the Circadian Clock in Response to Photoperiod: A Study in Male Melatonin-Competent Mice.
Olivia H Cox, Manuel A Giannoni-Guzmán, Jean-Philippe Cartailler, Matthew A Cottam, Douglas G McMahon

J Biol Rhythms· October 2024

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Disruption of nucleotide biosynthesis reprograms mitochondrial metabolism to inhibit adipogenesis.
Julia A Pinette, Jacob W Myers, Woo Yong Park, Heather G Bryant, Alex M Eddie, Matthew A Cottam

J Lipid Res· October 2024

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Calorie restriction increases insulin sensitivity to promote beta cell homeostasis and longevity in mice.
Cristiane Dos Santos, Amanda Cambraia, Shristi Shrestha, Melanie Cutler, Matthew Cottam

Nat Commun· October 2024

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Gli2 Overexpression Alters the Differentiation Status of Dedifferentiated Liposarcoma Cells and Results in an Immunosuppressive Myeloid Phenotype in Orthotopic Tumors.
Natalie E Bennett, Erik P Beadle, Dominique V Parker, Erykah J Coe, Matthew A Cottam

bioRxiv· September 2024

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Trem2 deficiency attenuates breast cancer tumor growth in lean, but not obese or weight loss, mice and is associated with alterations of clonal T cell populations.
Elysa W Pierro, Matthew A Cottam, Hanbing An, Brian D Lehmann, Jennifer A Pietenpol

bioRxiv· September 2024

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Author Correction: Obesity induces PD-1 on macrophages to suppress anti-tumour immunity.
Jackie E Bader, Melissa M Wolf, Gian Luca Lupica-Tondo, Matthew Z Madden, Bradley I Reinfeld, Matthew A Cottam

Nature· July 2024

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Obesity induces PD-1 on macrophages to suppress anti-tumour immunity.
Jackie E Bader, Melissa M Wolf, Gian Luca Lupica-Tondo, Matthew Z Madden, Bradley I Reinfeld, Matthew A Cottam

Nature· June 2024

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Gene expression plasticity of the mammalian brain circadian clock in response to photoperiod.
Olivia H Cox, Manuel A Gianonni-Guzmán, Jean-Philippe Cartailler, Matthew A Cottam, Douglas G McMahon

bioRxiv· March 2024

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Fructose regulates the pentose phosphate pathway and induces an inflammatory and resolution phenotype in Kupffer cells.
Mareca Lodge, Grace Scheidemantle, Victoria R Adams, Matthew A Cottam, Daniel Richard

Sci Rep· February 2024

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Immune profiling of murine cardiac leukocytes identifies triggering receptor expressed on myeloid cells 2 as a novel mediator of hypertensive heart failure.
Charles Duncan Smart, Daniel J Fehrenbach, Jean W Wassenaar, Vineet Agrawal, Niki L Fortune, Matthew A Cottam

Cardiovasc Res· October 2023

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Caloric restriction promotes beta cell longevity and delays aging and senescence by enhancing cell identity and homeostasis mechanisms.
Cristiane Dos Santos, Shristi Shrestha, Matthew Cottam, Guy Perkins, Varda Lev-Ram

Res Sq· September 2023

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Caloric restriction promotes beta cell longevity and delays aging and senescence by enhancing cell identity and homeostasis mechanisms.
Cristiane Dos Santos, Shristi Shrestha, Matthew Cottam, Guy Perkins, Varda Lev-Ram

bioRxiv· August 2023

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Weight cycling induces innate immune memory in adipose tissue macrophages.
Heather L Caslin, Matthew A Cottam, Jacqueline M Piñon, Likem Y Boney, Alyssa H Hasty

Front Immunol· January 2023

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Weight Cycling Impairs Pancreatic Insulin Secretion but Does Not Perturb Whole-Body Insulin Action in Mice With Diet-Induced Obesity.
Nathan C Winn, Matthew A Cottam, Monica Bhanot, Heather L Caslin, Jamie N Garcia

Diabetes· November 2022

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Multiomics reveals persistence of obesity-associated immune cell phenotypes in adipose tissue during weight loss and weight regain in mice.
Matthew A Cottam, Heather L Caslin, Nathan C Winn, Alyssa H Hasty

Nat Commun· May 2022

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Reactive oxygen species-degradable polythioketal urethane foam dressings to promote porcine skin wound repair.
Prarthana Patil, Katherine A Russo, Joshua T McCune, Alonda C Pollins, Matthew A Cottam

Sci Transl Med· April 2022

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Myeloid-specific deletion of ferroportin impairs macrophage bioenergetics but is disconnected from systemic insulin action in adult mice.
Nathan C Winn, Elysa M Wolf, Matthew A Cottam, Monica Bhanot, Alyssa H Hasty

Am J Physiol Endocrinol Metab· September 2021

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Exercise and Adipose Tissue Immunity: Outrunning Inflammation.
Nathan C Winn, Matthew A Cottam, David H Wasserman, Alyssa H Hasty

Obesity (Silver Spring)· May 2021

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