Publications by authors named "Matthew D Dun"

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Engineered CXCR3-A expression enhances B7-H3-targeting CAR T cell migration and efficacy against diffuse intrinsic pontine glioma.
Edward Z Song, Andrea Timpanaro, Michael Meechan, Leonel Elena-Sanchez, Lucy Z Li, Matthew D Dun

Nat Commun· November 2025

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Exposure of mice to environmentally relevant per- and polyfluoroalkyl substances (PFAS) alters the sperm epigenome.
Leah Gillespie, Jacinta H Martin, Amanda L Anderson, Ilana R Bernstein, Simone J Stanger, Matthew D Dun

Commun Biol· October 2025

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Hypomethylating agents induce epigenetic and transcriptional heterogeneity with implications for acute myeloid leukemia cell self-renewal.
Danielle R Bond, Sean M Burnard, Kumar Uddipto, Kooper V Hunt, Brooke M Harvey, Matthew D Dun

Leukemia· September 2025

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Preclinical efficacy of combinatorial B7-H3 CAR T cells and ONC206 against diffuse intrinsic pontine glioma.
Andrea Timpanaro, Edward Z Song, Ryma Toumi, Leonel Elena-Sanchez, Michael Meechan, Matthew D Dun

bioRxiv· September 2025

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Beyond Base Camp: Promise and Pitfalls of PI3K/mTOR Inhibition in Pediatric High- Grade Gliomas.
Ryan J Duchatel, Clara Savary, Zacary P Germon, Madisen Riley, David S Ziegler, Matthew D Dun

Res Sq· May 2025

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Intracerebroventricular B7-H3-targeting CAR T cells for diffuse intrinsic pontine glioma: a phase 1 trial.
Nicholas A Vitanza, Rebecca Ronsley, Michelle Choe, Kristy Seidel, Wenjun Huang, Matthew D Dun

Nat Med· March 2025

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Correction: Clinical Efficacy of ONC201 in H3K27M-Mutant Diffuse Midline Gliomas Is Driven by Disruption of Integrated Metabolic and Epigenetic Pathways.
Sriram Venneti, Abed Rahman Kawakibi, Sunjong Ji, Sebastian M Waszak, Stefan R Sweha, Matthew D Dun

Cancer Discov· March 2025

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Paediatric strategy forum for medicinal product development in diffuse midline gliomas in children and adolescents ACCELERATE in collaboration with the European Medicines Agency with participation of the Food and Drug Administration.
Andrew Dj Pearson, Sabine Mueller, Mariella G Filbin, Jacques Grill, Cynthia Hawkins, Matthew D Dun

Eur J Cancer· February 2025

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Think zebras: challenges and opportunities for treating rare cancers.
Sam Behjati, Jesse S Boehm, Matthew D Dun, Stefan Fröhling, Paul H Huang

Trends Cancer· February 2025

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EZHIP's role in diffuse midline glioma: echoes of oncohistones?
Afraah Cassim, Matthew D Dun, David Gallego-Ortega, Fatima Valdes-Mora

Trends Cancer· December 2024

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Subchronic elevation in ambient temperature drives alterations to the sperm epigenome and accelerates early embryonic development in mice.
Natalie Trigg, John E Schjenken, Jacinta H Martin, David A Skerrett-Byrne, Shannon P Smyth, Matthew D Dun

Proc Natl Acad Sci U S A· November 2024

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The oncolytic adenovirus Delta-24-RGD in combination with ONC201 induces a potent antitumor response in pediatric high-grade and diffuse midline glioma models.
Daniel de la Nava, Iker Ausejo-Mauleon, Virginia Laspidea, Marisol Gonzalez-Huarriz, Andrea Lacalle, Matthew D Dun

Neuro Oncol· August 2024

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Phosphoproteomic analysis of the adaption of epididymal epithelial cells to corticosterone challenge.
David A Skerrett-Byrne, Simone J Stanger, Natalie A Trigg, Amanda L Anderson, Petra Sipilä, Matthew D Dun

Andrology· July 2024

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Management of patients with diffuse intrinsic pontine glioma in Australia and New Zealand: Australian and New Zealand Children's Haematology/Oncology Group position statement.
Santosh Valvi, Neevika Manoharan, Marion K Mateos, Timothy Eg Hassall, David S Ziegler, Matthew D Dun

Med J Aust· June 2024

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Current status and advances to improving drug delivery in diffuse intrinsic pontine glioma.
Lauren M Arms, Ryan J Duchatel, Evangeline R Jackson, Pedro Garcia Sobrinho, Matthew D Dun

J Control Release· June 2024

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A review of current therapeutics targeting the mitochondrial protease ClpP in diffuse midline glioma, H3 K27-altered.
Evangeline R Jackson, Mika L Persson, Cameron J Fish, Izac J Findlay, Sabine Mueller, Matthew D Dun

Neuro Oncol· May 2024

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Diffuse midline glioma, H3K27-altered: Illuminating the dark side of the moon.
Matthew D Dun, Yazmin Odia, Isabel Arrillaga-Romany

Neuro Oncol· May 2024

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Pharmaco-phosphoproteomic analysis of cancer-associated KIT mutations D816V and V560G.
Heather C Murray, Kasey Miller, Matthew D Dun, Nicole M Verrills

Proteomics· May 2024

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PI3K/mTOR is a therapeutically targetable genetic dependency in diffuse intrinsic pontine glioma.
Ryan J Duchatel, Evangeline R Jackson, Sarah G Parackal, Dylan Kiltschewskij, Izac J Findlay, Matthew D Dun

J Clin Invest· February 2024

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Assessment of the impact of direct in vitro PFAS treatment on mouse spermatozoa.
Leah Calvert, Jacinta H Martin, Amanda L Anderson, Ilana R Bernstein, Nathan D Burke, Matthew D Dun

Reprod Fertil· January 2024

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CAR T cell therapies for diffuse midline glioma.
Bryce C Thomas, Dilana E Staudt, Alicia M Douglas, Michelle Monje, Nicholas A Vitanza, Matthew D Dun

Trends Cancer· October 2023

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Therapeutic HDAC inhibition in hypermutant diffuse intrinsic pontine glioma.
Alyssa Noll, Carrie Myers, Matthew C Biery, Michael Meechan, Sophie Tahiri, Matthew D Dun

Neoplasia· September 2023

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Crosstalk between DNA methylation and hypoxia in acute myeloid leukaemia.
Sam Humphries, Danielle R Bond, Zacary P Germon, Simon Keely, Anoop K Enjeti, Matthew D Dun

Clin Epigenetics· September 2023

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National brain tumour registry: a new era of research collaboration with China.
Santosh Valvi, Matthew D Dun, Jordan R Hansford

Lancet Reg Health West Pac· May 2023

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