Publications by authors named "Matthew D Lynes"

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12-Lipoxygenase Regulates Cold Adaptation and Glucose Metabolism by Producing the Omega-3 Lipid 12-HEPE from Brown Fat.
Luiz Osório Leiria, Chih-Hao Wang, Matthew D Lynes, Kunyan Yang, Farnaz Shamsi

Cell Metab· December 2025

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Promotion of Cardiovascular Homeostasis by the Perivascular Adipose Tissue Secretome.
Olivia R Whittaker, Matthew D Lynes, Ilka Pinz, Lucy Liaw

Int J Mol Sci· October 2025

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Towards a consensus atlas of human and mouse adipose tissue at single-cell resolution.
Anne Loft, Margo P Emont, Ada Weinstock, Adeline Divoux, Adhideb Ghosh, Matthew D Lynes

Nat Metab· May 2025

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Exploration of Conserved Human Adipose Subpopulations Using Targeted Single-Nuclei RNA Sequencing Data Sets.
Christian M Potts, Xuehui Yang, Matthew D Lynes, Kimberly Malka, Lucy Liaw

J Am Heart Assoc· March 2025

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Monitoring Mouse Surface Temperature During Stress with a Thermal Camera: A Low-Cost Infrared Videography System for Evaluating Murine Metabolism.
Breanna Page, Carolina Cora, James Reilly, Ryan Reno, Wadak Harbi, Maureen S Lynes, Michael A Lynes, Matthew D Lynes

Curr Protoc· February 2025

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Brown fat ATP-citrate lyase links carbohydrate availability to thermogenesis and guards against metabolic stress.
Ekaterina D Korobkina, Camila Martinez Calejman, John A Haley, Miranda E Kelly, Huawei Li, Matthew D Lynes

Nat Metab· November 2024

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Light-responsive adipose-hypothalamus axis controls metabolic regulation.
Tadataka Tsuji, Vladimir Tolstikov, Yang Zhang, Tian Lian Huang, Henrique Camara, Matthew D Lynes

Nat Commun· August 2024

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ScreenDMT reveals DiHOMEs are replicably inversely associated with BMI and stimulate adipocyte calcium influx.
Jonathan M Dreyfuss, Vera Djordjilović, Hui Pan, Valerie Bussberg, Allison M MacDonald, Matthew D Lynes

Commun Biol· August 2024

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Extracellular metallothionein as a therapeutic target in the early progression of type 1 diabetes.
Clare K Melchiorre, Matthew D Lynes, Sadikshya Bhandari, Sheng-Chiang Su, Christian M Potts, Michael A Lynes

Cell Stress Chaperones· April 2024

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A CRISPR Screen Identifies the E3 Ubiquitin Ligase Rfwd2 as a Negative Regulator of Glucose Uptake in Brown Adipocytes.
Matthew D Lynes, Qian Huang, Carolina Cora, Sheng-Chiang Su, Peng Yi

Genes (Basel)· September 2023

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ScreenDMT reveals linoleic acid diols replicably associate with BMI and stimulate adipocyte calcium fluxes.
Jonathan M Dreyfuss, Vera Djordjilovic, Hui Pan, Valerie Bussberg, Allison M MacDonald, Matthew D Lynes

bioRxiv· August 2023

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ADRA1A-Gα signalling potentiates adipocyte thermogenesis through CKB and TNAP.
Janane F Rahbani, Charlotte Scholtes, Damien M Lagarde, Mohammed F Hussain, Anna Roesler, Matthew D Lynes

Nat Metab· November 2022

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Endothelial Cells Induced Progenitors Into Brown Fat to Reduce Atherosclerosis.
Kyoungmin Park, Qian Li, Matthew D Lynes, Hisashi Yokomizo, Ernesto Maddaloni

Circ Res· July 2022

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Silk Hydrogel-Mediated Delivery of Bone Morphogenetic Protein 7 Directly to Subcutaneous White Adipose Tissue Increases Browning and Energy Expenditure.
Kristy L Townsend, Eleanor Pritchard, Jeannine M Coburn, Young Mi Kwon, Magdalena Blaszkiewicz, Matthew D Lynes

Front Bioeng Biotechnol· May 2022

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Telomerase Reverse Transcriptase Expression Marks a Population of Rare Adipose Tissue Stem Cells.
Matthew D Lynes, Diana L Carlone, Kristy L Townsend, David T Breault, Yu-Hua Tseng

Stem Cells· March 2022

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Vascular smooth muscle-derived Trpv1 progenitors are a source of cold-induced thermogenic adipocytes.
Farnaz Shamsi, Mary Piper, Li-Lun Ho, Tian Lian Huang, Anushka Gupta, Matthew D Lynes

Nat Metab· April 2021

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Defining the lineage of thermogenic perivascular adipose tissue.
Anthony R Angueira, Alexander P Sakers, Corey D Holman, Lan Cheng, Michelangella N Arbocco, Matthew D Lynes

Nat Metab· April 2021

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Brown Fat-Activating Lipokine 12,13-diHOME in Human Milk Is Associated With Infant Adiposity.
Danielle Wolfs, Matthew D Lynes, Yu-Hua Tseng, Stephanie Pierce, Valerie Bussberg

J Clin Endocrinol Metab· January 2021

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Endogenous Fatty Acid Synthesis Drives Brown Adipose Tissue Involution.
Christian Schlein, Alexander W Fischer, Frederike Sass, Anna Worthmann, Klaus Tödter, Matthew D Lynes

Cell Rep· January 2021

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Integrated metabolomics reveals altered lipid metabolism in adipose tissue in a model of extreme longevity.
Justin Darcy, Yimin Fang, Samuel McFadden, Matthew D Lynes, Luiz O Leiria

Geroscience· December 2020

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Commentary on: "The Presence of Active Brown Adipose Tissue Determines Cold-Induced Energy Expenditure and Oxylipin Profiles in Humans".
Matthew D Lynes, Yu-Hua Tseng

J Clin Endocrinol Metab· August 2020

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CRISPR-engineered human brown-like adipocytes prevent diet-induced obesity and ameliorate metabolic syndrome in mice.
Chih-Hao Wang, Morten Lundh, Accalia Fu, Rókus Kriszt, Tian Lian Huang, Matthew D Lynes

Sci Transl Med· August 2020

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FGF6 and FGF9 regulate UCP1 expression independent of brown adipogenesis.
Farnaz Shamsi, Ruidan Xue, Tian Lian Huang, Morten Lundh, Yang Liu, Matthew D Lynes

Nat Commun· March 2020

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Cell-autonomous light sensitivity via Opsin3 regulates fuel utilization in brown adipocytes.
Mari Sato, Tadataka Tsuji, Kunyan Yang, Xiaozhi Ren, Jonathan M Dreyfuss, Matthew D Lynes

PLoS Biol· February 2020

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Lipokines and Thermogenesis.
Matthew D Lynes, Sean D Kodani, Yu-Hua Tseng

Endocrinology· October 2019

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